A family-based weight loss randomized controlled trial for youth with intellectual disabilities

Details

• Alternative Title:
  Pediatr Obes
• Personal Author:
  Bandini, Linda G. ; Eliasziw, Misha ; Dittrich, Gretchen A. ; Curtin, Carol ; Maslin, Melissa ; Must, Aviva ; Boutelle, Kerri N. ; Fleming, Richard K.
• Description:
  Background:
  
  Scant data exist on weight loss interventions for youth with intellectual disabilities (ID).
  
  Objective:
  
  To compare weight loss among youth with ID randomized to a 6-month, family-based behavioural intervention (FBBI) or a waitlist and to compare weight loss among youth who completed a 6-month maintenance (FBBI-M) intervention to a control group (FBBI-C).
  
  Methods:
  
  Youth with ID and overweight/obesity, aged 14–22 years, were randomized to the FBBI or to a waitlist and subsequently randomized to a maintenance intervention or a control group. Sessions were held weekly during the FBBI and biweekly during the FBBI-M. Using an intention-to-treat approach, we used linear mixed models to test differences in the change in weight and in BMI from the start of FBBI.
  
  Results:
  
  The 24 participants who received the FBBI lost, on average (SE), 5.1 (1.1) kg (P < .001) over 6 months. The 13 participants who were waitlisted gained, on average (SE), 1.2 (1.6) kg over the 6-month waiting period. At 12 months, those who received FBBI-M lost, on average (SE), 4.4 (1.7) kg more than those who received FBBI-C (−7.6 vs −3.2 kg, P-value = .008).
  
  Conclusion:
  
  Participation in an intensive FBBI for weight loss with ID was efficacious, and continued participation in a maintenance intervention yielded additional weight loss.
  
  
• Subjects:
  Adolescent Humans Intellectual Disability Weight Loss
• Keywords:
  Alzheimer's Disease Alzheimer's Disease Sequencing Project Antiviral Agents Family-based Behavioural Intervention Herpes Simplex Human Papillomavirus Intellectual Disabilities Randomized Control Trial Torque Teno Viruses Weight Loss Whole Exome Sequencing Whole Genome Sequencing Youth

  More +
• Source:
  Pediatr Obes. 16(11):e12816
• Pubmed ID:
  34076370
• Pubmed Central ID:
  PMC9100997
• Document Type:
  Journal Article
• Funding:
  P30 HD004147/HD/NICHD NIH HHSUnited States/ ; R01 HD072573/HD/NICHD NIH HHSUnited States/ ; U58 DD000564/DD/NCBDD CDC HHSUnited States/
• Volume:
  16
• Issue:
  11
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:a90740a3dec4126947603176c72ac9aa6bbd923f42cf7ff26e0fb5572c89fdaaea3ccefa34b65227c9c484591f5948a27604ca68fec02716c61f30598b5aadb4
• Download URL:
  https://stacks.cdc.gov/view/cdc/117332/cdc_117332_DS1.pdf
• File Type:
  [PDF - 907.29 KB ]