Effectiveness of COVID-19 MRNA Vaccination in Preventing COVID-19–associated Hospitalization Among Adults with Previous SARS-CoV-2 Infection — U.S. June 2021–February 2022

Plumb, Ian D.; Feldstein, Leora R.; Barkley, Eric; Posner, Alexander B.; Bregman, Howard S.; Hagen, Melissa Briggs; Gerhart, Jacqueline L.

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

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Effectiveness of COVID-19 MRNA Vaccination in Preventing COVID-19–associated Hospitalization Among Adults with Previous SARS-CoV-2 Infection — U.S. June 2021–February 2022

April 12, 2022
By Plumb, Ian D. ; Feldstein, Leora R. ; Barkley, Eric ; ...
Source: MMWR: Morbidity and Mortality Weekly Report 2022; v. 71 Early Release
Series: Weekly Report: Morbidity and Mortality Weekly Report (MMWR)

[PDF-363.69 KB]

English

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Details:

Personal Author:

Plumb, Ian D. ; Feldstein, Leora R. ; Barkley, Eric ; Posner, Alexander B. ; Bregman, Howard S. ; ... More +

Plumb, Ian D. ; Feldstein, Leora R. ; Barkley, Eric ; Posner, Alexander B. ; Bregman, Howard S. ; Hagen, Melissa Briggs ; Gerhart, Jacqueline L. Less -
Corporate Authors:

National Center for Immunization and Respiratory Diseases (U.S.) ; Div. of Viral Diseases ; CDC COVID-19 Emergency Response Team ; Epic Systems Corporation

National Center for Immunization and Respiratory Diseases (U.S.) ; Div. of Viral Diseases ; CDC COVID-19 Emergency Response Team ; Epic Systems Corporation Less -
Description:

What is already known about this topic? Persons with previous SARS-CoV-2 infection have some protection against reinfection leading to hospitalization, but there is limited evidence regarding the additional benefit of vaccination among these persons.

What is added by this report? Among persons with previous infection, COVID-19 mRNA vaccination provided protection against subsequent COVID-19–associated hospitalization. Estimated vaccine effectiveness against reinfection leading to hospitalization during the Omicron-predominant period was approximately 35% after dose 2, and 68% after a booster dose.

What are the implications for public health practice? To prevent COVID-19–associated hospitalization, all eligible persons should stay up to date with vaccination, including those with previous SARS-CoV-2 infection.

Suggested citation for this article: Suggested citation for this article: Plumb ID, Feldstein LR, Barkley E, et al. Effectiveness of COVID-19 mRNA Vaccination in Preventing COVID-19–Associated Hospitalization Among Adults with Previous SARS-CoV-2 Infection — U.S. June 2021–February 2022. MMWR Morb Mortal Wkly Rep. ePub: 12 April 2022.

mm7115e2.htm?s_cid=mm7115e2_w

mm7115e2-H.pdf
Subjects:

[+]

2019-nCoV Vaccine MRNA-1273 Adults BNT162 Vaccine COVID-19 Vaccines COVID-19/Prevention & Control Hospitalization SARS-CoV-2 Vaccination
Source:

MMWR: Morbidity and Mortality Weekly Report 2022; v. 71 Early Release
Series:

Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
ISSN:

0149-2195 (print);1545-861X (digital);
Document Type:

Journal Article
Place as Subject:

U.S.
Pages in Document:

7 pdf pages
Volume:

71
Collection(s):

Morbidity and Mortality Weekly Report (MMWR)
Main Document Checksum:

[+]

urn:sha-512:19e194fb483b4ad12e8954ebc7c57907464228f5671e39ac14dbceb9879cdbe02283155179c236aa90824b52589e78710599bcb39075f3b6ec7b02a9db314dc7
Download URL:

https://stacks.cdc.gov/view/cdc/116190/cdc_116190_DS1.pdf
File Type:

mm7115e2.htm

bin

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