Details:

Alternative Title:
COPD
Publisher's site:
http://dx.doi.org/10.1080/15412555.2016.1216956
Personal Author:
DeVries, Rebecca ; Kriebel, David ; Sama, Susan
DeVries, Rebecca ; Kriebel, David ; Sama, Susan Less -
Description:
A systematic literature review was performed to identify all peer-reviewed literature quantifying the association between short-term exposures of particulate matter <2.5 microns (PM|), nitrogen dioxide (NO|), and sulfur dioxide (SO|) and COPD-related emergency department (ED) visits, hospital admissions (HA), and mortality. These results were then pooled for each pollutant through meta-analyses with a random effects model. Subgroup meta-analyses were explored to study the effects of selected lag/averaging times and health outcomes. A total of 37 studies satisfied our inclusion criteria, contributing to a total of approximately 1,115,000 COPD-related acute events (950,000 HAs, 80,000 EDs, and 130,000 deaths) to our meta-estimates. An increase in PM| of 10 ug/m| was associated with a 2.5% (95% CI: 1.6-3.4%) increased risk of COPD-related ED and HA, an increase of 10 ug/m| in NO| was associated with a 4.2% (2.5-6.0%) increase, and an increase of 10 ug/m| in SO| was associated with a 2.1% (0.7-3.5%) increase. The strength of these pooled effect estimates, however, varied depending on the selected lag/averaging time between exposure and outcome. Similar pooled effects were estimated for each pollutant and COPD-related mortality. These results suggest an ongoing threat to the health of COPD patients from both outdoor particulates and gaseous pollutants. Ambient outdoor concentrations of PM|, NO|, and SO| were significantly and positively associated with both COPD-related morbidity and mortality.
Subject:
[+]
Air Pollution Article Disease Progression Emergency Service, Hospital Environmental Epidemiology Environmental Health Humans Nitrogen Dioxide Particulate Matter Patient Admission Pulmonary Disease, Chronic Obstructive Respiratory Disease Sulfur Dioxide Time Factors Air Pollution
Source:
COPD. 14(1):113-121
Pubmed ID:
27564008
Pubmed Central ID:
PMC8994423
Document Type:
Journal Article
Funding:
R21 ES017849/ES/NIEHS NIH HHSUnited States/ ; T01 OH008424/OH/NIOSH CDC HHSUnited States/
R21 ES017849/ES/NIEHS NIH HHSUnited States/ ; T01 OH008424/OH/NIOSH CDC HHSUnited States/ Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:57090a1ba1cb38c68c0c93b8772ccc03db55aaa7726a64d8754bc96e4d80238b
Download URL:
https://stacks.cdc.gov/view/cdc/116107/cdc_116107_DS1.pdf
File Type:

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