Details:

Alternative Title:
COPD
Personal Author:
DeVries, Rebecca ; Kriebel, David ; Sama, Susan
DeVries, Rebecca ; Kriebel, David ; Sama, Susan Less -
Description:
A systematic literature review was performed to identify all peer-reviewed literature quantifying the association between short-term exposures of particulate matter <2.5 microns (PM|), nitrogen dioxide (NO|), and sulfur dioxide (SO|) and COPD-related emergency department (ED) visits, hospital admissions (HA), and mortality. These results were then pooled for each pollutant through meta-analyses with a random effects model. Subgroup meta-analyses were explored to study the effects of selected lag/averaging times and health outcomes. A total of 37 studies satisfied our inclusion criteria, contributing to a total of approximately 1,115,000 COPD-related acute events (950,000 HAs, 80,000 EDs, and 130,000 deaths) to our meta-estimates. An increase in PM| of 10 ug/m| was associated with a 2.5% (95% CI: 1.6-3.4%) increased risk of COPD-related ED and HA, an increase of 10 ug/m| in NO| was associated with a 4.2% (2.5-6.0%) increase, and an increase of 10 ug/m| in SO| was associated with a 2.1% (0.7-3.5%) increase. The strength of these pooled effect estimates, however, varied depending on the selected lag/averaging time between exposure and outcome. Similar pooled effects were estimated for each pollutant and COPD-related mortality. These results suggest an ongoing threat to the health of COPD patients from both outdoor particulates and gaseous pollutants. Ambient outdoor concentrations of PM|, NO|, and SO| were significantly and positively associated with both COPD-related morbidity and mortality.
Subjects:
[+]
Air Pollution Article Disease Progression Emergency Service, Hospital Environmental Epidemiology Environmental Health Humans Nitrogen Dioxide Particulate Matter Patient Admission Pulmonary Disease, Chronic Obstructive Respiratory Disease Sulfur Dioxide Time Factors
Source:
COPD. 14(1):113-121
Pubmed ID:
27564008
Pubmed Central ID:
PMC8994423
Document Type:
Journal Article
Funding:
R21 ES017849/ES/NIEHS NIH HHSUnited States/ ; T01 OH008424/OH/NIOSH CDC HHSUnited States/
R21 ES017849/ES/NIEHS NIH HHSUnited States/ ; T01 OH008424/OH/NIOSH CDC HHSUnited States/ Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:57090a1ba1cb38c68c0c93b8772ccc03db55aaa7726a64d8754bc96e4d80238b
Download URL:
https://stacks.cdc.gov/view/cdc/116107/cdc_116107_DS1.pdf
File Type:

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