Outdoor Air Pollution and COPD Related Emergency Department Visits, Hospital Admissions and Mortality: A Meta-Analysis

Details

• Alternative Title:
  COPD
• Personal Author:
  DeVries, Rebecca ; Kriebel, David ; Sama, Susan
• Description:
  A systematic literature review was performed to identify all peer-reviewed literature quantifying the association between short-term exposures of particulate matter <2.5 microns (PM|), nitrogen dioxide (NO|), and sulfur dioxide (SO|) and COPD-related emergency department (ED) visits, hospital admissions (HA), and mortality. These results were then pooled for each pollutant through meta-analyses with a random effects model. Subgroup meta-analyses were explored to study the effects of selected lag/averaging times and health outcomes. A total of 37 studies satisfied our inclusion criteria, contributing to a total of approximately 1,115,000 COPD-related acute events (950,000 HAs, 80,000 EDs, and 130,000 deaths) to our meta-estimates. An increase in PM| of 10 ug/m| was associated with a 2.5% (95% CI: 1.6-3.4%) increased risk of COPD-related ED and HA, an increase of 10 ug/m| in NO| was associated with a 4.2% (2.5-6.0%) increase, and an increase of 10 ug/m| in SO| was associated with a 2.1% (0.7-3.5%) increase. The strength of these pooled effect estimates, however, varied depending on the selected lag/averaging time between exposure and outcome. Similar pooled effects were estimated for each pollutant and COPD-related mortality. These results suggest an ongoing threat to the health of COPD patients from both outdoor particulates and gaseous pollutants. Ambient outdoor concentrations of PM|, NO|, and SO| were significantly and positively associated with both COPD-related morbidity and mortality.
• Subjects:
  Air Pollution Disease Progression Emergency Service, Hospital Humans Nitrogen Dioxide Particulate Matter Patient Admission Pulmonary Disease, Chronic Obstructive Sulfur Dioxide Time Factors
• Keywords:
  Air Pollution Environmental Epidemiology Environmental Health Respiratory Disease
• Source:
  COPD. 14(1):113-121
• Pubmed ID:
  27564008
• Pubmed Central ID:
  PMC8994423
• Document Type:
  Journal Article
• Funding:
  R21 ES017849/ES/NIEHS NIH HHSUnited States/ ; T01 OH008424/OH/NIOSH CDC HHSUnited States/
• Volume:
  14
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:90dbc44cc760c354795c86266f44b1b6e0f69c5a9d7b92b51405788eda02dfe30c8809b8c463e511cf9914bebae24d0ded961d5a34c7b179afcca2bac2d897d6
• Download URL:
  https://stacks.cdc.gov/view/cdc/116107/cdc_116107_DS1.pdf
• File Type:
  [PDF - 740.62 KB ]