Progress Toward Achieving and Sustaining Maternal and Neonatal Tetanus Elimination — Worldwide, 2000–2020

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Kanu, Florence A. ; Yusuf, Nasir ; Kassogue, Modibo ; Ahmed, Bilal ; Tohme, Rania A.
• Description:
  Maternal and neonatal tetanus (MNT)* remains a major cause of neonatal Mortality with an 80%-100% case-fatality rate among insufficiently vaccinated mothers after unhygienic deliveries, especially in low-income countries (1). In 1989, the World Health Assembly endorsed elimination| of neonatal tetanus; the activity was relaunched in 1999 as the MNT elimination (MNTE)| initiative, targeting 59| priority countries. MNTE strategies include 1) achieving ≥80% coverage with ≥2 doses of tetanus toxoid-containing vaccine (TTCV2+)** among women of reproductive age through routine and supplementary immunization activities (SIAs)| in high-risk districts,| 2) achieving ≥70% of deliveries by a skilled birth attendant,| and 3) implementing neonatal tetanus case-based Surveillance (2). This report summarizes progress toward achieving and sustaining MNTE during 2000-2020 and updates a previous report (3). By December 2020, 52 (88%) of 59 priority countries had conducted TTCV SIAs. Globally, infants protected at birth*** against tetanus increased from 74% (2000) to 86% (2020), and deliveries assisted by a skilled birth attendant increased from 64% (2000-2006) to 83% (2014-2020). Reported neonatal tetanus cases Worldwide decreased by 88%, from 17,935 (2000) to 2,229 (2020), and estimated deaths decreased by 92%, from 170,829 (2000) to 14,230 (2019).| By December 2020, 47 (80%) of 59 priority countries were validated to have achieved MNTE, five of which conducted postvalidation assessments.| To achieve elimination in the 12 remaining countries and sustain elimination, innovation is needed, including integrating SIAs to cover multiple vaccine preventable Diseases and implementing TTCV life course vaccination.
• Subjects:
  Adult Developing Countries Disease Eradication Female Health Priorities Humans Immunization Programs Infant, Newborn Infant Health Maternal Health Middle Aged Tetanus Tetanus Toxoid Vaccination Coverage

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• Source:
  MMWR Morbidity Mortal Weekly Rep. 71(11):406-411
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• DOI:
  http://dx.doi.org/10.15585/mmwr.mm7111a2
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  35298457
• Pubmed Central ID:
  PMC8942310
• Document Type:
  Journal Article
• Pages in Document:
  6 pdf pages
• Volume:
  71
• Issue:
  11
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:a3207b32a6c7ad965b747734f50db8fec051dc593c0cbfcad1544508c7ad9a8f841962e9c6ff1e638e32bf2f27b1c3e3ca9ef5c84b047af3d57af54c845ca537
• Download URL:
  https://stacks.cdc.gov/view/cdc/115840/cdc_115840_DS1.pdf
• File Type:
  [PDF - 216.18 KB ]