SARS-CoV-2 B.1.1.529 (Omicron) Variant Transmission Within Households — Four U.S. Jurisdictions, November 2021–February 2022

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Baker, Julia M. ; Nakayama, Jasmine Y. ; O’Hegarty, Michelle ; McGowan, Andrea ; Teran, Richard A. ; Bart, Stephen M. ; Mosack, Katie ; Roberts, Nicole ; Campos, Brooke ; Paegle, Alina ; McGee, John ; Herrera, Robert ; English, Kayla ; Barrios, Carla ; Davis, Alexandria ; Roloff, Christine ; Sosa, Lynn E. ; Brockmeyer, Jessica ; Page, Lindsey ; Bauer, Amy ; Weiner, Joshua J. ; Khubbar, Manjeet ; Bhattacharyya, Sanjib ; Kirking, Hannah L. ; Tate, Jacqueline E.
• Description:
  The B.1.1.529 (Omicron) Variants, first detected in November 2021, was responsible for a surge in U.S. infections with SARS-CoV-2, the Virus that causes COVID-19, during December 2021-January 2022 (1). To investigate the effectiveness of Prevention strategies in household settings, CDC partnered with four U.S. jurisdictions to describe Omicron household Transmission during November 2021-February 2022. Persons with sequence-confirmed Omicron infection and their household contacts were interviewed. Omicron Transmission occurred in 124 (67.8%) of 183 households. Among 431 household contacts, 227 were classified as having a case of COVID-19 (attack rate [AR] = 52.7%).| The ARs among household contacts of index patients who had received a COVID-19 booster dose, of fully vaccinated index patients who completed their COVID-19 primary series within the previous 5 months, and of unvaccinated index patients were 42.7% (47 of 110), 43.6% (17 of 39), and 63.9% (69 of 108), respectively. The AR was lower among household contacts of index patients who isolated (41.2%, 99 of 240) compared with those of index patients who did not isolate (67.5%, 112 of 166) (p-value <0.01). Similarly, the AR was lower among household contacts of index patients who ever wore a mask at home during their potentially infectious period (39.5%, 88 of 223) compared with those of index patients who never wore a mask at home (68.9%, 124 of 180) (p-value <0.01). Multicomponent COVID-19 Prevention strategies, including up-to-date vaccination, isolation of infected persons, and mask use at home, are critical to reducing Omicron Transmission in household settings.
• Subjects:
  Adolescent Adult Aged Child Child, Preschool Contact Tracing COVID-19 Family Characteristics Female Humans Incidence Infant Male Middle Aged SARS-CoV-2 Serial Infection Interval Vaccination

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• Source:
  MMWR Morbidity Mortal Weekly Rep. 71(9):341-346
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• DOI:
  http://dx.doi.org/10.15585/MMWRmm7109e1
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  35238860
• Pubmed Central ID:
  PMC8893332
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Pages in Document:
  6 pdf pages
• Volume:
  71
• Issue:
  9
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:4a3f9297abf9251a272fd1d4f8847dc42a484f57f86d3d0f01c49d03c060269bb3d3660e2f091038b4215118bcff60f56ef6627fb91c9b96d1a31363e255993f
• Download URL:
  https://stacks.cdc.gov/view/cdc/115829/cdc_115829_DS1.pdf
• File Type:
  [PDF - 166.18 KB ]