Hospitalization of infants and children aged 0–4 years with laboratory-confirmed COVID-19 — COVID-NET, 14 states, March 2020–February 2022

Marks, Kristin J.; Whitaker, Michael; Agathis, Nickolas T.; Anglin, Onika; Milucky, Jennifer; Patel, Kadam; Pham, Huong; Kirley, Pam Daily; Kawasaki, Breanna; Meek, James; Anderson, Evan J.; Weigel, Andy; Kim, Sue; Lynfield, Ruth; Ropp, Susan L.; Spina, Nancy L.; Bennett, Nancy M.; Shiltz, Eli; Sutton, Melissa; Talbot, H. Keipp; Price,, Andrea; Taylor, Christopher A.; Havers, Fiona P.

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Hospitalization of infants and children aged 0–4 years with laboratory-confirmed COVID-19 — COVID-NET, 14 states, March 2020–February 2022

March 15, 2022
By Marks, Kristin J. ; Whitaker, Michael ; Agathis, Nickolas T. ; ...
Series: MMWR; v. 71, ER, 3/15/22

[PDF-289.62 KB]

English

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Details:

Personal Author:

Marks, Kristin J. ; Whitaker, Michael ; Agathis, Nickolas T. ; Anglin, Onika ; Milucky, Jennifer ; ... More +

Marks, Kristin J. ; Whitaker, Michael ; Agathis, Nickolas T. ; Anglin, Onika ; Milucky, Jennifer ; Patel, Kadam ; Pham, Huong ; Kirley, Pam Daily ; Kawasaki, Breanna ; Meek, James ; Anderson, Evan J. ; Weigel, Andy ; Kim, Sue ; Lynfield, Ruth ; Ropp, Susan L. ; Spina, Nancy L. ; Bennett, Nancy M. ; Shiltz, Eli ; Sutton, Melissa ; Talbot, H. Keipp ; Price,, Andrea ; Taylor, Christopher A. ; Havers, Fiona P. Less -
Corporate Authors:

COVID-NET Surveillance Team ; CDC COVID-19 Emergency Response Team ; Centers for Disease Control and Prevention (U.S.) ; Epidemic Intelligence Service ; General Dynamics Information Technology ; ... More +

COVID-NET Surveillance Team ; CDC COVID-19 Emergency Response Team ; Centers for Disease Control and Prevention (U.S.) ; Epidemic Intelligence Service ; General Dynamics Information Technology ; California Emerging Infections Program ; Colorado Dept. of Public Health and Environment ; Yale University School of Public Health Connecticut Emerging Infections Program ; Emory University School of Medicine ; Georgia Emerging Infections Program ; Veterans Affairs Medical Center Atlanta, Ga. ; Iowa Dept. of Health ; Michigan. Dept. of Health and Human Services ; Minnesota Dept. of Health ; New Mexico Dept. of Health ; New York State Dept. of Health ; University of Rochester School of Medicine and Dentistry ; University of Rochester Medical Center ; Rochester Emerging Infections Program ; Ohio Dept. of Health ; Oregon Health Authority Public Health Div. ; Vanderbilt University Medical Center ; Salt Lake County, UT Health Dept. Less -
Description:

What is already known about this topic? COVID-19 can cause severe illness in infants and children, including those aged 0–4 years who are not yet eligible for COVID-19 vaccination.

What is added by this report? During Omicron Variants predominance beginning in late December 2021, U.S. infants and children aged 0–4 years were hospitalized at approximately five times the rate of the previous peak during Delta Variants predominance. Infants aged <6 months had the highest rates of hospitalization, but indicators of severity (e.g., respiratory support) did not differ by age group.

What are the implications for public health practice?

Important strategies to prevent COVID-19 among infants and young children include vaccination of currently eligible populations such as pregnant women, family members, and caregivers of infants and young children.

The B.1.1.529 (Omicron) Variants of SARS-CoV-2, the Virus that causes COVID-19, has been the predominant circulating Variants in the U.S. since late December 2021.* Coinciding with increased Omicron circulation, COVID-19–associated hospitalization rates increased rapidly among infants and children aged 0–4 years, a group not yet eligible for vaccination (1). CoronaVirus Disease 19–Associated Hospitalization Surveillance Network (COVID-NET)† data were analyzed to describe COVID-19–associated hospitalizations among U.S. infants and children aged 0–4 years since March 2020. During the period of Omicron predominance (December 19, 2021–February 19, 2022), weekly COVID-19–associated hospitalization rates per 100,000 infants and children aged 0–4 years peaked at 14.5 (week ending January 8, 2022); this Omicron-predominant period peak was approximately five times that during the period of SARS-CoV-2 B.1.617.2 (Delta) predominance (June 27–December 18, 2021, which peaked the week ending September 11, 2021).§ During Omicron predominance, 63% of hospitalized infants and children had no underlying medical conditions; infants aged <6 months accounted for 44% of hospitalizations, although no differences were observed in indicators of severity by age. Strategies to prevent COVID-19 among infants and young children are important and include vaccination among currently eligible populations (2) such as pregnant women (3), family members, and caregivers of infants and young children (4).

Suggested citation for this article: Marks KJ, Whitaker M, Agathis NT, et al. Hospitalization of Infants and Children Aged 0–4 Years with Laboratory-Confirmed COVID-19 — COVID-NET, 14 States, March 2020–February 2022. MMWR Morb Mortal Wkly Rep. ePub: 15 March 2022.

mm7111e2.htm?s_cid=mm7111e2_w

mm7111e2-H.pdf
Subjects:

[+]

Adolescent Child Child, Preschool CoronaVirus Infections COVID-19 Hospitalization Humans Incidence Infant Infant, Newborn Population Surveillance SARS-CoV-2 Vaccination
Series:

MMWR; v. 71, ER, 3/15/22
Document Type:

Journal Article
Name as Subject:

COVID-19 ; COVID-19

COVID-19 ; COVID-19 Less -
Place as Subject:

California ; Colorado ; Connecticut ; Georgia ; Iowa ; ... More +

California ; Colorado ; Connecticut ; Georgia ; Iowa ; Maryland ; Michigan ; Minnesota ; New Mexico ; New York ; Ohio ; Oregon ; Tennessee ; Utah Less -
Pages in Document:

8 numbered pages
Volume:

71
Collection(s):

Morbidity and Mortality Weekly Report (MMWR)
Main Document Checksum:

[+]

urn:sha256:4c771270fd0194ccc694ec71b656c842c85906c3afa0153577ab3c08e9c7cb4c
Download URL:

https://stacks.cdc.gov/view/cdc/115432/cdc_115432_DS1.pdf
File Type:

mm7111e2.htm

htm

More +