Invasive Burkholderia cepacia Complex Infections among Persons Who Inject Drugs, Hong Kong, China, 2016–2019

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Luk, Kristine Shik ; Tsang, Yat-ming ; Ho, Alex Yat-man ; To, Wing-kin ; Wong, Ben Kwok-ho ; Wong, Maureen Mo-lin ; Wong, Yiu-chung
• Description:
  During March 2016-January 2019, Burkholderia cepacia complex (BCC) infection developed in 13 persons who inject drugs (PWID) in Kowloon West Region, Hong Kong, China. Seven cases were infective spondylitis, 2 endocarditis, 2 septic arthritis, 1 intramuscular abscess and bacteremia, and 1 necrotizing fasciitis. Pulsed-field gel electrophoresis revealed that the isolates from 9 patients were clonally related. This clone caused major illness, and 11 of the 13 patients required surgical treatment. Clinicians should be aware of this pathogen and the appropriate broad-spectrum antimicrobial drugs to empirically prescribe for PWID with this life-threatening infection. Close collaboration among public health authorities, outreach social workers, and methadone clinics is essential for timely prevention and control of outbreaks in the PWID population.
• Subjects:
  Bacteria Burkholderia Burkholderia Cepacia Complex Disease Outbreak Drug Users Persons Who Inject Drugs Pulsed-Field Gel Electrophoresis
• Source:
  Emerg Infect Dis. 2022; 28(2):323-330
• Pubmed ID:
  34906288
• Pubmed Central ID:
  PMC8798689
• Document Type:
  Journal Article
• Place as Subject:
  Hong Kong
• Volume:
  28
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:2e108ae035bd0e9879e2c56b2f7dd18c0d5e34949730402b521af83d03f716e9
• Download URL:
  https://stacks.cdc.gov/view/cdc/114531/cdc_114531_DS1.pdf
• File Type:
  [PDF - 1023.29 KB ]