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Hospitalizations of children and adolescents with laboratory-confirmed COVID-19 — COVID-NET, 14 states, July 2021–January 2022
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February 15, 2022
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Series: MMWR; v. 71, ER, 2/15/22
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Description:What is already known about this topic? COVID-19 can cause severe illness in children and adolescents.
What is added by this report? Coinciding with increased circulation of the Omicron Variants, COVID-19–associated hospitalization rates among children and adolescents aged 0–17 years increased rapidly in late December 2021, especially among children aged 0–4 years who are not yet eligible for vaccination. Throughout the periods of Delta and Omicron predominance, hospitalization rates remained lower among fully vaccinated adolescents aged 12–17 years than among unvaccinated adolescents.
What are the implications for public health practice? Strategies to prevent COVID-19 among children and adolescents, including vaccination of eligible persons, are critical.
The first U.S. case of COVID-19 attributed to the Omicron Variants of SARS-CoV-2 (the Virus that causes COVID-19) was reported on December 1, 2021 (1), and by the week ending December 25, 2021, Omicron was the predominant circulating Variants in the U.S.* Although COVID-19–associated hospitalizations are more frequent among adults,† COVID-19 can lead to severe outcomes in children and adolescents (2). This report analyzes data from the CoronaVirus Disease 19–Associated Hospitalization Surveillance Network (COVID-NET)§ to describe COVID-19–associated hospitalizations among U.S. children (aged 0–11 years) and adolescents (aged 12–17 years) during periods of Delta (July 1–December 18, 2021) and Omicron (December 19, 2021–January 22, 2022) predominance. During the Delta- and Omicron-predominant periods, rates of weekly COVID-19–associated hospitalizations per 100,000 children and adolescents peaked during the weeks ending September 11, 2021, and January 8, 2022, respectively. The Omicron Variants peak (7.1 per 100,000) was four times that of the Delta Variants peak (1.8), with the largest increase observed among children aged 0–4 years.¶ During December 2021, the monthly hospitalization rate among unvaccinated adolescents aged 12–17 years (23.5) was six times that among fully vaccinated adolescents (3.8). Strategies to prevent COVID-19 among children and adolescents, including vaccination of eligible persons, are critical.
Suggested citation for this article: Marks KJ, Whitaker M, Anglin O, et al. Hospitalizations of Children and Adolescents with Laboratory-Confirmed COVID-19 — COVID-NET, 14 States, July 2021–January 2022. MMWR Morb Mortal Wkly Rep. ePub: 15 February 2022.
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