Details:

Alternative Title:
J Addict Med
Publisher's site:
http://dx.doi.org/10.1097/ADM.0000000000000725
Personal Author:
Nolan, Nathanial S. ; Marks, Laura R. ; Liang, Stephen Y. ; Durkin, Michael J.
Nolan, Nathanial S. ; Marks, Laura R. ; Liang, Stephen Y. ; Durkin, Michael J. Less -
Description:
Objectives:

To identify the incidence, characteristics and factors associated with against medical advice (AMA) discharge among hospitalized patients with opioid use disorder (OUD) and injection related infections (e.g., endocarditis, osteomyelitis, epidural abscesses).

Methods:

This retrospective cohort study evaluated adults with OUD admitted to an academic medical center from 1/1/2016-7/1/2019 for an invasive injection related infection. Multivariable logistic regression was used to determine independent factors associated with AMA discharge.

Results:

Among 262 adults admitted with serious injection related infections and comorbid OUD, 138 received inpatient medications for opioid use disorder (MOUD). Univariate analysis showed a decreased odds ratio (OR) of AMA discharge when patients received MOUD inpatient (OR 0.55; 95% CI 0.34-0.91.). Adjusting for covariates associated with social determinants of health and other substance use, inpatient receipt of MOUD was associated with a decreased risk of AMA discharge (adjusted OR 0.49; 95% CI 0.028 – 0.84).

Conclusions:

Among patients with OUD and serious injection related infections, inpatient initiation of MOUD is associated with decreased risk of AMA discharge.


Subjects:
[+]
Adult Article Drug Users Endocarditis Humans Opioid-Related Disorders Opioid Use Disorder Osteomyelitis Patient Discharge Persons Who Inject Drugs Pharmaceutical Preparations Retrospective Studies Substance Abuse, Intravenous
Source:
J Addict Med. 15(2):155-158
Pubmed ID:
32804690
Pubmed Central ID:
PMC7995266
Document Type:
Journal Article
Funding:
KL2 TR002346/TR/NCATS NIH HHSUnited States/ ; L30 AI133778/AI/NIAID NIH HHSUnited States/ ; T32 AI007172/AI/NIAID NIH HHSUnited States/ ; U54 CK000609/CK/NCEZID CDC HHSUnited States/
KL2 TR002346/TR/NCATS NIH HHSUnited States/ ; L30 AI133778/AI/NIAID NIH HHSUnited States/ ; T32 AI007172/AI/NIAID NIH HHSUnited States/ ; U54 CK000609/CK/NCEZID CDC HHSUnited States/ Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:db9a50e65284aa7212d266ee2782ac54108c2f06c53af25be26d6c84a896d324
Download URL:
https://stacks.cdc.gov/view/cdc/114232/cdc_114232_DS1.pdf
File Type:

Supporting Files

• nihms-1679963.nxml

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