Growing Disparity in the Incidence of Colorectal Cancer among Non-Hispanic American Indian and Alaska Native Populations—United States, 2013–2017

Details

• Alternative Title:
  Cancer Epidemiol Biomarkers Prev
• Personal Author:
  Haverkamp, Donald ; Melkonian, Stephanie C. ; Jim, Melissa A.
• Description:
  Background:
  
  American Indian and Alaska Native (AI/AN) populations have experienced regional variation and disparities in colorectal cancer incidence rates.
  
  Methods:
  
  We examined colorectal cancer incidence (2013–2017) and colorectal cancer incidence trends (1999–2017) among AI/AN persons. Incidence data were linked to Indian Health Service enrollment records, and analyses were restricted to Purchased/Referred Care Delivery Areas. Incidence rates of colorectal cancer among AI/AN and White persons were analyzed in six geographic regions; Hispanic persons were excluded. Incidence trends were analyzed using linear modeling.
  
  Results:
  
  During 2013–2017, colorectal cancer incidence was 41% higher among AI/AN than among White persons. AI/AN incidence rates per 100,000 varied regionally from 34.4 in the East to 96.1 in Alaska. Compared with White persons, AI/AN persons had higher colorectal cancer incidence rates among all age strata and were more likely to have late-stage diagnoses. Incidence rate trends indicated significant increases among both AI/AN and White persons ages <50 years and among AI/AN persons ages 50–64 years. The colorectal cancer incidence rate trend increased among AI/AN persons in the Southwest.
  
  Conclusions:
  
  The disparity of colorectal cancer incidence rates between AI/AN and White persons has widened since 2005–2009. AI/AN populations have higher colorectal cancer incidence compared with White populations, especially in the Alaska region.
  
  Impact:
  
  Our finding of increased colorectal cancer incidence disparities suggests that enhanced screening efforts and culturally appropriate clinical and public health interventions are needed among AI/AN persons overall, and especially in regions and age groups in which colorectal cancer rates are increasing.
  
  
• Subjects:
  Alaskan Natives American Indians Or Alaska Natives Colorectal Neoplasms Humans Incidence Indians, North American Middle Aged Registries
• Source:
  Cancer Epidemiol Biomarkers Prev. 30(10):1799-1806
• Pubmed ID:
  34341050
• Pubmed Central ID:
  PMC8590617
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Place as Subject:
  Alaska ; United States
• Volume:
  30
• Issue:
  10
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:d2b3fd3496b5c60a3a5e5b51990cfd6f54edc92729bb4c619a57f4765d3ca9ca
• Download URL:
  https://stacks.cdc.gov/view/cdc/111712/cdc_111712_DS1.pdf
• File Type:
  [PDF - 132.74 KB ]