Distribution of SARS-CoV-2 Variants in a Large Integrated Health Care System — California, March–July 2021
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Distribution of SARS-CoV-2 Variants in a Large Integrated Health Care System — California, March–July 2021

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English
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Details:

  • Alternative Title:
    MMWR Morb Mortal Wkly Rep
  • Personal Author:
  • Description:
    Data from observational studies demonstrate that Variantss of SARS-CoV-2, the Virus that causes COVID-19, have evolved rapidly across many countries (1,2). The SARS-CoV-2 B.1.617.2 (Delta) Variants of concern is more transmissible than previously identified Variantss,* and as of September 2021, is the predominant Variants in the United States| Studies characterizing the distribution and severity of illness caused by SARS-CoV-2 Variantss, particularly the Delta Variants, are limited in the United States (3), and are subject to limitations related to study setting, specimen collection, study population, or study period (4-7). This study used whole genome sequencing (WGS) data on SARS-CoV-2-positive specimens collected across Kaiser Permanente Southern California (KPSC), a large integrated health care system, to describe the distribution and risk of hospitalization associated with SARS-CoV-2 Variantss during March 4-July 21, 2021, by patient vaccination status. Among 13,039 SARS-CoV-2-positive specimens identified from KPSC patients during this period, 6,798 (52%) were sequenced and included in this report. Of these, 5,994 (88%) were collected from unvaccinated persons, 648 (10%) from fully vaccinated persons, and 156 (2%) from partially vaccinated persons. Among all sequenced specimens, the weekly percentage of B.1.1.7 (Alpha) Variants infections increased from 20% to 67% during March 4-May 19, 2021. During April 15-July 21, 2021, the weekly percentage of Delta Variants infections increased from 0% to 95%. During March 4-July 21, 2021, the weekly percentage of Variantss was similar among fully vaccinated and unvaccinated persons, but the Delta Variants was more commonly identified among vaccinated persons then unvaccinated persons overall, relative to other Variantss. The Delta Variants was more prevalent among younger persons, with the highest percentage (55%) identified among persons aged 18-44 years. Infections attributed to the Delta Variants were also more commonly identified among non-Hispanic Black persons, relative to other Variantss. These findings reinforce the importance of continued monitoring of SARS-CoV-2 Variantss and implementing multiple COVID-19 Prevention strategies, particularly during the current period in which Delta is the predominant Variants circulating in the United States
  • Subjects:
  • Source:
    MMWR Morb Mortal Wkly Rep. 70(40):1415-1419
  • Pubmed ID:
    34618801
  • Pubmed Central ID:
    PMC8519275
  • Document Type:
    Journal Article
  • Place as Subject:
    California
  • Collection(s):
  • Main Document Checksum:
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