Laboratory-confirmed COVID-19 Among Adults Hospitalized with COVID-19–like Illness with Infection-induced or MRNA Vaccine-induced SARS-CoV-2 Immunity — Nine States, January–September 2021
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October 29, 2021
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Personal Author:Bozio, Catherine H. ; Grannis, Shaun J. ; Naleway, Allison L. ; Ong, Toan C. ; Butterfield, Kristen A. ; DeSilva, Malini B. ; Natarajan, Karthik ; Yang, Duck-Hye ; Rao, Suchitra ; Klein, Nicola P. ; Irving, Stephanie A. ; Dixon, Brian E. ; Dascomb, Kristin ; Liao, I-Chia ; Reynolds, Sue ; McEvoy, Charlene ; Han, Jungmi ; Reese, Sarah E. ; Lewis, Ned ; Fadel, William F. ; Grisel, Nancy ; Murthy, Kempapura ; Ferdinands, Jill ; Kharbanda, Anupam B. ; Mitchell, Patrick K. ; Goddard, Kristin ; Embi, Peter J. ; Arndorfer, Julie ; Raiyani, Chandni ; Patel, Palak ; Rowley, Elizabeth A. ; Fireman, Bruce ; Valvi, Nimish R. ; Griggs, Eric P. ; Levy, Matthew E. ; Zerbo, Ousseny ; Porter, Rachael M. ; Birch, Rebecca J. ; Blanton, Lenee ; Ball, Sarah W. ; Steffens, Andrea ; Olson, Natalie ; Williams, Jeremiah ; Dickerson, Monica ; McMorrow, Meredith ; Schrag, Stephanie J. ; Verani, Jennifer R. ; Fry, Alicia M. ; Azziz-Baumgartner, Eduardo ; Barron, Michelle ; Gaglani, Manjusha ; Thompson, Mark G. ; Stenehjem, Edward
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Corporate Authors:CDC COVID-19 Response Team. ; Regenstrief Institute for Health Care. Center for Biomedical Informatics. ; Indiana University School of Medicine. ; Center for Health Research (Kaiser-Permanente Medical Care Program. Northwest Region) ; University of Colorado Anschutz Medical Campus. Department of Medicine. ; Westat, inc. ; HealthPartners Institute. ; Columbia University. Department of Biomedical Informatics. ; New York Presbyterian Hospital. ; Kaiser Permanente Vaccine Study Center. ; Indiana University. Fairbanks School of Public Health. ; Intermountain Healthcare (Utah). Division of Infectious Diseases and Clinical Epidemiology. ; Texas A&M University College of Medicine. Baylor Scott & White Health. ; Children’s Minnesota (Minneapolis, Minnesota) ; Regenstrief Institute. ; VISION Institute.
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Description:What is already known about this topic? Previous infection with SARS-CoV-2 or COVID-19 vaccination can provide immunity and protection against subsequent SARS-CoV-2 infection and illness.
What is added by this report? Among COVID-19–like illness hospitalizations among adults aged ≥18 years whose previous infection or vaccination occurred 90–179 days earlier, the adjusted odds of laboratory-confirmed COVID-19 among unvaccinated adults with previous SARS-CoV-2 infection were 5.49-fold higher than the odds among fully vaccinated recipients of an mRNA COVID-19 vaccine who had no previous documented infection (95% confidence interval = 2.75–10.99).
What are the implications for public health practice? All eligible persons should be vaccinated against COVID-19 as soon as possible, including unvaccinated persons previously infected with SARS-CoV-2.
Suggested citation for this article: Bozio CH, Grannis SJ, Naleway AL, et al. Laboratory-Confirmed COVID-19 Among Adults Hospitalized with COVID-19–Like Illness with Infection-Induced or mRNA Vaccine-Induced SARS-CoV-2 Immunity — Nine States, January–September 2021. MMWR Morb Mortal Wkly Rep. ePub: 29 October 2021.
mm7044e1.htm?s_cid=mm7044e1_w
mm7044e1-H.pdf
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Subjects:
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Source:MMWR: Morbidity and Mortality Weekly Report 2021; v. 70 Early Release
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Series:
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ISSN:0149-2195 (print) ; 1545-861X (digital)
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Pages in Document:6 pdf pages
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Volume:70
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Main Document Checksum:urn:sha-512:3abe097ed1e5530be86c4caa2e736c847865d0537b9c29763b01f7365e737b30be70c3d61cdf9fe4faaea8b1e5b19488dc23c35b6929977bbb0ea0b0ad30cc25
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Morbidity and Mortality Weekly Report (MMWR)