Effectiveness of Pfizer-BioNTech MRNA Vaccination Against COVID-19 Hospitalization Among Persons Aged 12–18 Years — United States, June–September 2021

Details

• Personal Author:
  Olson, Samantha M. ; Newhams, Margaret M. ; Halasa, Natasha B. ; Price, Ashley M. ; Boom, Julie A. ; Sahni, Leila C. ; Irby, Katherine ; Walker, Tracie C. ; Schwartz, Stephanie P. ; Pannaraj, Pia S. ; Maddux, Aline B. ; Bradford, Tamara T. ; Nofziger, Ryan A. ; Boutselis, Benjamin J. ; Cullimore, Melissa L. ; Mack, Elizabeth H. ; Schuster, Jennifer E. ; Gertz, Shira J. ; Cvijanovich, Natalie Z. ; Kong, Michele ; Cameron, Melissa A. ; Staat, Mary A. ; Levy, Emily R. ; Chatani, Brandon M. ; Chiotos, Kathleen ; Zambrano, Laura D. ; Campbell, Angela P. ; Patel, Manish M. ; Randolph, Adrienne G.
• Corporate Authors:
  CDC COVID-19 Response Team. ; Boston Children’s Hospital. Department of Anesthesiology, Critical Care, and Pain Medicine. ; Vanderbilt University Medical Center. Department of Pediatrics. Division of Pediatric Infectious Diseases. ; Baylor College of Medicine. Department of Pediatrics. Immunization Project. ; Arkansas Children’s Hospital. Department of Pediatrics. Section of Pediatric Critical Care. ; University of North Carolina at Chapel Hill Children’s Hospital. Department of Pediatrics. ; Children’s Hospital Los Angeles and Departments of Pediatrics and Molecular Microbiology and Immunology. Division of Infectious Diseases. ; University of Colorado School of Medicine and Children’s Hospital Colorado. Department of Pediatrics, Section of Critical Care Medicine. ; Louisiana State University Health Sciences Center and Children’s Hospital of New Orleans. Department of Pediatrics, Division of Cardiology. ; Akron Children’s Hospital. Department of Pediatrics. Division of Critical Care Medicine. ; Children’s Hospital and Medical Center. Department of Pediatrics. Division of Pediatric Critical Care. ; Medical University of South Carolina. Division of Pediatric Critical Care Medicine. ; Children’s Mercy Kansas City. Department of Pediatrics. Division of Pediatric Infectious Diseases. ; Saint Barnabas Medical Center (Livingston, New Jersey). Department of Pediatrics. Division of Pediatric Critical Care. ; University of California, San Francisco. Division of Critical Care Medicine. Benioff Children’s Hospital Oakland (Oakland, CA) ; University of Alabama at Birmingham. Department of Pediatrics. Division of Pediatric Critical Care Medicine. ; University of California San Diego-Rady Children’s Hospital. Division of Pediatric Hospital Medicine. ; University of Cincinnati College of Medicine. Cincinnati Children’s Hospital Medical Center. Department of Pediatrics. ; Mayo Clinic. Department of Pediatric and Adolescent Medicine. Divisions of Pediatric Infectious Diseases and Pediatric Critical Care Medicine. ; UHealth/Holtz Children’s Hospital. Department of Pediatrics. Division of Pediatric Infectious Diseases. ; Hospital of Philadelphia. Department of Anesthesiology and Critical Care, Children’s. Division of Critical Care Medicine. ; Harvard Medical School, Boston. Departments of Anesthesia and Pediatrics.
• Description:
  What is already known about this topic? Persons aged 12–18 years are eligible to receive COVID-19 vaccine. Currently, data are lacking on real-world vaccine effectiveness against COVID-19 hospitalization in adolescents.
  
  What is added by this report? Among hospitalized U.S. patients aged 12–18 years, vaccine effectiveness of 2 doses of Pfizer-BioNTech vaccine against COVID-19 hospitalization during June–September 2021, was 93% (95% confidence interval = 83%–97%).
  
  What are the implications for public health practice? This evaluation demonstrated that 2 doses of Pfizer-BioNTech vaccine were highly effective in preventing COVID-19 hospitalization among persons aged 12–18 years. Findings reinforce the importance of vaccination to protect U.S. youths against severe COVID-19.
  
  Suggested citation for this article: Olson SM, Newhams MM, Halasa NB, et al. Effectiveness of Pfizer-BioNTech mRNA Vaccination Against COVID-19 Hospitalization Among Persons Aged 12–18 Years — United States, June–September 2021. MMWR Morb Mortal Wkly Rep. ePub: 19 October 2021.
  
  mm7042e1.htm?s_cid=mm7042e1_w
  
  mm7042e1-H.pdf
  
  
• Subjects:
  Adolescent CoronaVirus Infections/Prevention & Control COVID-19 Vaccines Vaccines, Synthetic
• Source:
  MMWR: Morbidity and Mortality Weekly Report 2021; v. 70 Early Release
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Document Type:
  Journal Article
• Name as Subject:
  Pfizer-BioNTech COVID-19 Vaccine ; COMIRNATY
• Pages in Document:
  6 pdf pages
• Volume:
  70
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:fdb1c3c6c83b6b4918c6bddc73b2d34f4dcbc8f2a6a6cf6ca7ba93f1f259c45c5595f70f6f3ed73b0ecb1e6b55b1514f1cac62024b144015ca1801f86b898f63
• Download URL:
  https://stacks.cdc.gov/view/cdc/110833/cdc_110833_DS1.pdf
• File Type:
  [PDF - 235.70 KB ]