Details:

Alternative Title:
MMWR Morb Mortal Wkly Rep
Personal Author:
Rosenberg, Eli S. ; Holtgrave, David R. ; Dorabawila, Vajeera ; Conroy, MaryBeth ; Greene, Danielle ; ... More +
Rosenberg, Eli S. ; Holtgrave, David R. ; Dorabawila, Vajeera ; Conroy, MaryBeth ; Greene, Danielle ; Lutterloh, Emily ; Backenson, Bryon ; Hoefer, Dina ; Morne, Johanne ; Bauer, Ursula ; Zucker, Howard A. Less -
Description:
Data from randomized clinical trials and real-world observational studies show that all three COVID-19 vaccines currently authorized for emergency use by the Food and Drug Administration* are safe and highly effective for preventing COVID-19-related serious illness, hospitalization, and death (1,2). Studies of vaccine effectiveness (VE) for preventing new infections and hospitalizations attributable to SARS-CoV-2, the Virus that causes COVID-19), particularly as the B.1.617.2 (Delta) Variants has become predominant, are limited in the U.S. (3). In this study, the New York State Department of Health linked statewide immunization, laboratory tTesting, and hospitalization databases for New York to estimate rates of new laboratory-confirmed COVID-19 cases and hospitalizations by vaccination status among adults, as well as corresponding VE for full vaccination in the population, across all three authorized vaccine products. During May 3-July 25, 2021, the overall age-adjusted VE against new COVID-19 cases for all adults declined from 91.8% to 75.0%. During the same period, the overall age-adjusted VE against hospitalization was relatively stable, ranging from 89.5% to 95.1%. Currently authorized vaccines have high effectiveness against COVID-19 hospitalization, but effectiveness against new cases appears to have declined in recent months, coinciding with the Delta Variants's increase from <2% to >80% in the U.S. region that includes New York and relaxation of masking and physical distancing recommendations. To reduce new COVID-19 cases and hospitalizations, these findings support the implementation of a layered approach centered on vaccination, as well as other Prevention strategies such as masking and physical distancing.
Subjects:
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Adolescent Adult Aged Clinical Laboratory Techniques CoronaVirus Infections COVID-19 COVID-19 Vaccines Hospitalization Humans Middle Aged SARS-CoV-2 Vaccination Young Adult
Source:
MMWR Morb Mortal Wkly Rep. 70(37):1306-1311
Pubmed ID:
34529645
Pubmed Central ID:
PMC8445378
Document Type:
Journal Article
Genre:
Corrected and Republished Article
Place as Subject:
New York
Collection(s):
Morbidity and Mortality Weekly Report (MMWR)
Main Document Checksum:
[+]
urn:sha256:769fbe5de30ee99de8dca7039089b8adc73f23e04c3c0867f5aed9851783a3ee
Download URL:
https://stacks.cdc.gov/view/cdc/110251/cdc_110251_DS1.pdf
File Type:

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