Interim clinical considerations for use of COVID-19 vaccines currently authorized in the United States
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Interim clinical considerations for use of COVID-19 vaccines currently authorized in the United States

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  • Description:
    COVID-19 vaccination is recommended for everyone aged 12 years and older for the prevention of coronavirus disease 2019 (COVID-19) in the United States under the FDA Emergency Use Authorization (EUA). The Advisory Committee on Immunization Practices (ACIP) has issued interim recommendations for the use of:

    • Pfizer-BioNTech COVID-19 vaccine (in persons aged 12–15 years and aged ≥16 years)

    • Moderna COVID-19 vaccine (in persons aged ≥18 years)

    • Janssen (Johnson & Johnson) COVID-19 vaccine (in persons aged ≥18 years)

  • Content Notes:
    Background -- Authorized age groups for COVID-19 vaccination -- COVID-19 vaccine administration -- Interchangeability of COVID-19 vaccine products -- People vaccinated for COVID-19 outside the United States -- Coadministration of COVID-19 vaccines with other vaccines -- COVID-19 vaccination and SARS-CoV-2 infection -- Antiviral therapy and COVID-19 vaccination -- Vaccinating people with a known COVID-19 exposure or during COVID-19 outbreaks -- Considerations for use of an additional dose of COVID-19 vaccine following a primary vaccine series -- Considerations for use of an additional mRNA COVID-19 vaccine dose after an initial 2-dose COVID-19 mRNA vaccine series for immunocompromised people -- Considerations for vaccination of people with certain underlying medical conditions -- Considerations for use of the Janssen COVID-19 vaccine in certain populations -- Considerations involving pregnancy, lactation, and fertility -- Vaccination of children and adolescents -- Patient counseling -- Contraindications and precautions -- Reporting of vaccine adverse events -- Laboratory testing -- Appendix A. Vaccine administration errors and deviations -- Appendix B: Triage of people presenting for COVID-19 vaccination -- Appendix C: Ingredients included in COVID-19 vaccines -- Appendix D: Potential characteristics of allergic reactions, vasovagal reactions, and vaccine side effects following COVID-19 vaccination -- References -- Previous Updates.
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