Pediatric Q Fever

Details

• Alternative Title:
  Curr Infect Dis Rep
• Personal Author:
  Cherry, Cara C. ; Kersh, Gilbert J.
• Description:
  Purpose of Review ; The non-specific presentation of acute Q fever makes it difficult to diagnose in children, but untreated Q fever can result in chronic infections that have severe complications. ; Recent Findings ; Pediatric Q fever cases continue to be infrequently reported in the literature, and primarily document cases of persistent infections with Coxiella burnetii. Standardized treatment protocols for chronic Q fever in children still do not exist. Doxycycline and hydroxychloroquine are the treatment combination most utilized by healthcare providers to treat Q fever endocarditis or osteomyelitis in children, but a variety of other antibiotic combinations have been reported with varying results. The use of adjunctive therapies, such as such as interferon gamma, has produced mixed outcomes. ; Summary ; The true impact of Coxiella burnetii on the health of children remains unknown; long-term longitudinal follow-up of children with acute or chronic Q fever has not been reported. Both the acute and chronic forms of Q fever are underreported and underdiagnosed. Healthcare providers should consider Q fever in pediatric patients with culture-negative endocarditis or osteomyelitis.
• Subjects:
  • Child
  • Coxiella burnetii
  • Pediatrics
  • Q Fever
• Source:
  Curr Infect Dis Rep. 22(4)
• Pubmed ID:
  34135692
• Pubmed Central ID:
  PMC8205507
• Document Type:
  Text
• Funding:
  CC999999/ImCDC/Intramural CDC HHS/United States
• Genre:
  Journal Article
• Volume:
  22
• Issue:
  4
• Download URL:
  https://stacks.cdc.gov/view/cdc/107403/cdc_107403_DS1.pdf
• File Type:
  [PDF - 426.42 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:1fe73489726320958c620f0fe300e25f4f1c7a078b7d4a90819acc7a00d38102076fa0392dbcbe3645df0a8d4bac63f73154f98a5766ac529c983bccf6fb3aec