Follow-Up of the Libby, Montana Screening Cohort

Details

• Alternative Title:
  J Occup Environ Med
• Personal Author:
  Larson, Theodore C. ; Williamson, Laura ; Antao, Vinicius C.
• Description:
  Objective:
  
  To evaluate mortality patterns among participants in a community-based screening program for asbestos-related disease.
  
  Methods:
  
  We calculated standardized mortality ratios (SMRs) and stratified results by exposure group (three occupational exposure groups, household contacts and residents without occupational asbestos exposure) and by radiographic abnormality presence.
  
  Results:
  
  All-cause mortality (15.8%; 1,429/8,043) was statistically lower than expected. Asbestosis was statistically elevated in all exposure groups. Lung cancer was moderately associated with vermiculite miner/miller employment. Mesothelioma was elevated in that same exposure group and among residents. Systemic autoimmune disease mortality was also elevated. Radiographic parenchymal abnormalities were associated with lung cancer mortality.
  
  Conclusion:
  
  In addition to asbestos-related mortality in occupational exposure groups, this initial follow-up of this cohort also shows elevated mortality for some asbestos-related causes in non-occupational exposure groups.
  
  
• Subjects:
  Adult Aluminum Silicates Asbestos Asbestos, Amphibole Asbestosis Biometry Cohort Studies Environmental Exposure Female Follow-Up Studies Humans Lung Lung Neoplasms Male Mesothelioma Middle Aged Occupational Exposure

  More +
• Keywords:
  Asbestos Asbestosis Chest Radiograph Mesothelioma Mortality
• Source:
  J Occup Environ Med. 62(1):e1-e6
• Pubmed ID:
  31714372
• Pubmed Central ID:
  PMC8157313
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Place as Subject:
  Montana
• Volume:
  62
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:dc7f70d2d1a60373e9bcb4e9b0863a11d5007ad8ff2fde272d3565fba40be963
• Download URL:
  https://stacks.cdc.gov/view/cdc/106687/cdc_106687_DS1.pdf
• File Type:
  [PDF - 86.37 KB ]