Determination of 226Ra in Urine Using Triple Quadrupole Inductively Coupled Plasma Mass Spectrometry

Details

• Alternative Title:
  Radiat Prot Dosimetry
• Personal Author:
  Xiao, Ge ; Liu, Yongzhong ; Jones, Robert L.
• Description:
  Measuring 226Ra in urine at low levels is critical for both biomonitoring and radiological emergency response. Here we report a new analytical method to quantify 226Ra, as developed and validated by a simple dilute-and-shoot procedure, followed by Inductively Coupled Plasma-triple quadrupole-mass spectrometry detection using 'No Gas MS-MS' mode. The method provides rapid and accurate results for 226Ra with a limit of detection (LOD) down to 0.007 ng/l (0.26 Bq/l). This LOD is well below the recommended action levels for 226Ra detection in children and pregnant women (C/P) set by the Clinical Decision Guide (NCRP Report #161). Results for 226Ra obtained by this method are within ±7.0% of the target values of standard reference materials spiked in the urine.
• Subjects:
  Article
• Source:
  Radiat Prot Dosimetry.
• Pubmed ID:
  33184663
• Pubmed Central ID:
  PMC8116344
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:55ab954d3bfbbf721e4a77baed47aec53736636dbdc680a97c4e2eb9196fc941
• Download URL:
  https://stacks.cdc.gov/view/cdc/106222/cdc_106222_DS1.pdf
• File Type:
  [PDF - 499.34 KB ]