Interim estimates of vaccine effectiveness of Pfizer-BioNTech and Moderna Covid-19 Vaccines among health care personnel — 33 U.S. sites, January–March 2021

Pilishvili, Tamara; Fleming-Dutra, Katherine E.; Farrar, Jennifer L.; Gierke, Ryan; Mohr, Nicholas M.; Talan, David A.; Krishnadasan, Anusha; Harland, Karisa K.; Smithline, Howard A.; Hou, Peter C.; Lee, Lilly C.; Lim, Stephen C.; Moran, Gregory J.; Krebs, Elizabeth; Steele, Mark; Beiser, David G.; Faine, Brett; Haran, MD, John P.; Nandi, Utsav; Schrading, Walter A.; Chinnock, Brian; Henning, Daniel J.; LoVecchio, Frank; Nadle, Joelle; Barter, Devra; Brackney, Monica; Britton, Amber; Marceaux-Galli, Kaytlynn; Lim, Sarah; Phipps, Erin C.; Dumyati, Ghinwa; Pierce, Rebecca; Markus, Tiffanie M.; Anderson, Deverick J.; Debes, Amanda K.; Lin, Michael; Mayer, Jeanmarie; Babcock, Hilary M.; Safdar, Nasia; Fischer, Marc; Singleton, Rosalyn; Chea, Nora; Magill, Shelley S.; Verani, Jennifer; Schrag, Stephanie

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Interim estimates of vaccine effectiveness of Pfizer-BioNTech and Moderna Covid-19 Vaccines among health care personnel — 33 U.S. sites, January–March 2021

May 14, 2021
By Pilishvili, Tamara ; Fleming-Dutra, Katherine E. ; Farrar, Jennifer L. ; ...
Series: MMWR. Morbidity and Mortality Weekly Report ; v. 70, early release, May 14, 2021

[PDF-144.72 KB]

English

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Details:

Personal Author:

Pilishvili, Tamara ; Fleming-Dutra, Katherine E. ; Farrar, Jennifer L. ; Gierke, Ryan ; Mohr, Nicholas M. ; ... More +

Pilishvili, Tamara ; Fleming-Dutra, Katherine E. ; Farrar, Jennifer L. ; Gierke, Ryan ; Mohr, Nicholas M. ; Talan, David A. ; Krishnadasan, Anusha ; Harland, Karisa K. ; Smithline, Howard A. ; Hou, Peter C. ; Lee, Lilly C. ; Lim, Stephen C. ; Moran, Gregory J. ; Krebs, Elizabeth ; Steele, Mark ; Beiser, David G. ; Faine, Brett ; Haran, MD, John P. ; Nandi, Utsav ; Schrading, Walter A. ; Chinnock, Brian ; Henning, Daniel J. ; LoVecchio, Frank ; Nadle, Joelle ; Barter, Devra ; Brackney, Monica ; Britton, Amber ; Marceaux-Galli, Kaytlynn ; Lim, Sarah ; Phipps, Erin C. ; Dumyati, Ghinwa ; Pierce, Rebecca ; Markus, Tiffanie M. ; Anderson, Deverick J. ; Debes, Amanda K. ; Lin, Michael ; Mayer, Jeanmarie ; Babcock, Hilary M. ; Safdar, Nasia ; Fischer, Marc ; Singleton, Rosalyn ; Chea, Nora ; Magill, Shelley S. ; Verani, Jennifer ; Schrag, Stephanie Less -
Corporate Authors:

CDC COVID- Response Team ; University of Iowa. ; Olive View–University of California Los Angeles Medical Center, Los Angeles, California ; Baystate Medical Center, Springfield, Massachusetts ; Brigham and Women’s Hospital, Boston, Massachusetts ; ... More +

CDC COVID- Response Team ; University of Iowa. ; Olive View–University of California Los Angeles Medical Center, Los Angeles, California ; Baystate Medical Center, Springfield, Massachusetts ; Brigham and Women’s Hospital, Boston, Massachusetts ; Jackson Memorial Hospital. ; Louisiana State University. ; Thomas Jefferson University Hospital. ; Truman Medical Center. ; University of Chicago. ; University of Massachusetts. ; University of Mississippi. ; University of Alabama at Birmingham. ; University of California San Francisco. ; University of Washington. ; Valleywise Health Medical Center (Phoenix, Arizona) ; California Emerging Infections Program. ; Colorado. Department of Public Health and Environment. ; Connecticut Emerging Infections Program. ; Georgia Emerging Infections Program. ; Emory University School of Medicine. ; Maryland. Department of Health. ; Minnesota. Department of Health. Minnesota Emerging Infections Program. ; University of New Mexico. ; New Mexico Emerging Infections Program. ; University of Rochester Medical Center. New York State—Rochester Emerging Infections Program. ; Oregon Health Authority. Public Health Division. ; Vanderbilt University Medical Center. ; Duke University School of Medicine. Duke Center for Antimicrobial Stewardship and Infection Prevention. ; Johns Hopkins School of Public Health. ; Rush University Medical Center. Department of Medicine. ; University of Utah/VA Salt Lake City Health Care System. ; Washington University (St. Louis, Mo.). School of Medicine. ; University of Wisconsin—Madison. ; William S. Middleton Memorial Veterans Hospital (Madison, Wisconsin) ; Alaska Native Tribal Health Consortium. Less -
Description:

What is already known about this topic? Health care personnel (HCP) are at high risk for COVID-19. The early distribution of two mRNA COVID-19 vaccines (Pfizer-BioNTech and Moderna) to HCP provided an opportunity to examine vaccine effectiveness in a real-world setting.

What is added by this report? The first U.S. multisite test-negative design vaccine effectiveness study among HCP found a single dose of Pfizer-BioNTech or Moderna Covid-19 Vaccines to be 82% effective against symptomatic COVID-19 and 2 doses to be 94% effective.

What are the implications for public health practice? The mRNA vaccines are highly effective at preventing symptomatic COVID-19 among U.S. HCP. High vaccination coverage among HCP and the general population is critical to prevent COVID-19 in the United Statesmm7020e2.htm?s_cid=mm7020e2_w

mm7020e2-H.pdf
Subjects:

[+]

CoronaVirus Infections/Prevention & Control COVID-19 Vaccines COVID-19/Prevention & Control Health Personnel Vaccines, Synthetic
Series:

MMWR. Morbidity and Mortality Weekly Report ; v. 70, early release, May 14, 2021
Document Type:

Journal Article
Name as Subject:

Moderna Covid-19 Vaccine ; Pfizer-BioNTech COVID-19 Vaccine ; Moderna Covid-19 Vaccine ; Pfizer-BioNTech COVID-19 Vaccine

Moderna Covid-19 Vaccine ; Pfizer-BioNTech COVID-19 Vaccine ; Moderna Covid-19 Vaccine ; Pfizer-BioNTech COVID-19 Vaccine Less -
Place as Subject:

United States
Collection(s):

Morbidity and Mortality Weekly Report (MMWR)
Main Document Checksum:

[+]

urn:sha256:ce1a71ff3380d2cb08b69a657d6f30cc8d4524e1f5b04e444e6acdb9c3e38c4c
Download URL:

https://stacks.cdc.gov/view/cdc/106200/cdc_106200_DS1.pdf
File Type:

mm7020e2.htm

htm

More +