SARS-COV-2 ANTIBODY PREVALENCE AMONG HEALTHCARE WORKERS AND FIRST RESPONDERS, FLORIDA, MAY-JUNE 2020

Details

• Alternative Title:
  Fla Public Health Rev
• Personal Author:
  Matthias, James ; Spencer, Emma C ; Michniewicz, Mara ; Bendle, Thomas M ; Wilson, Craig ; Scheppke, Kenneth A ; Blackmore, Carina ; Otis, Aaron ; Rivkees, Scott A
• Description:
  Background:
  
  The SARS-CoV-2 virus responsible for severe respiratory infection associated with coronavirus disease 2019 (COVID-19) was first confirmed in Florida on March 1, 2020. Responding to the pandemic, multi-agency collaborative partnerships put in place actions integrating point-of-care antibody testing at established large-scale COVID-19 testing sites where the baseline seropositivity of COVID-19 in health care workers and first responders in Florida at the start of the pandemic was established.
  
  Purpose:
  
  Determine the seropositivity of healthcare workers and first responders at five drive thru testing sites using a rapid SARS-CoV-2 antibody test in Florida from May 6 through June 3, 2020.
  
  Methods:
  
  The first drive-thru SARS-CoV-2 antibody test site was opened at Miami Hard Rock Stadium, May 6, 2020. Testing expanded to three additional sites on May 9, 2020: Jacksonville, Orlando, and Palm Beach. The fifth and final site, Miami Beach, began testing on May 21, 2020. Healthcare workers and first responder’s self-seeking SARS-CoV-2 testing were designated for antibody testing and completed a laboratory collection form onsite for the point-of-care test. All testing was performed on whole blood specimens (obtained by venipuncture) using the Cellex Inc. qSARS-CoV-2 IgG/IgM Rapid Test. Seropositivity was assessed by univariate analysis and by logistic regression including the covariates age, sex, race/ethnicity, and testing location.
  
  Results and Discussion:
  
  As of June 3, 2020, of 5,779 healthcare workers and first responders tested, 4.1% were seropositive (range 2.6–8.2%). SARS-COV-2 antibody tests had higher odds of being positive for persons testing at the Miami Hard Rock Stadium (aOR 2.24 [95% C.I. 1.48–3.39]), persons of Haitian/Creole ethnicity (aOR 3.28 [95% C.I. 1.23–8.72]), Hispanic/Latino(a) ethnicity (aOR 2.17 [95% C.I. 1.50–3.13], and Black non-Hispanic persons (aOR 1.63 [95% C.I. 1.08–2.46]). SARS-COV-2 antibody prevalence among first responders and healthcare workers in five sites in Florida varied by race and ethnicity and by testing location.
  
  
• Source:
  Fla Public Health Rev. 18(1):1-10
• Pubmed ID:
  33851146
• Pubmed Central ID:
  PMC8040388
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  18
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:b2728a66e1fc740da8087ecd3d7f8d3ccfe11ea35f2294fef201b30269f0dcb6c3204f115f15b3aad42fbea172a908d2842c96121af6e4da4c7b9a48f8ef190e
• Download URL:
  https://stacks.cdc.gov/view/cdc/105265/cdc_105265_DS1.pdf
• File Type:
  [PDF - 262.69 KB ]