Effective Antibiotic Conservation by Emergency Antimicrobial Stewardship During a Drug Shortage

Details

• Alternative Title:
  Infect Control Hosp Epidemiol
• Personal Author:
  Hsueh, Kevin ; Angeles, Maria Reyes ; Krekel, Tamara ; Casabar, Ed ; Ritchie, David ; Jafarzadeh, S. Reza ; Lane, Michael A. ; Hays, Amanda ; Durkin, Michael J.
• Description:
  We present the first description of an antimicrobial stewardship program (ASP) used to successfully manage a multi-antimicrobial drug shortage. Without resorting to formulary restriction, meropenem utilization decreased by 69% and piperacillin-tazobactam by 73%. During the shortage period, hospital mortality decreased (P=.03), while hospital length of stay remained unchanged. Infect Control Hosp Epidemiol 2017;38:356-359.
• Subjects:
  Academic Medical Centers Anti-Bacterial Agents Antimicrobial Stewardship Hospital Mortality Humans Length Of Stay Linear Models Meropenem Penicillanic Acid Piperacillin Piperacillin, Tazobactam Drug Combination Retrospective Studies Thienamycins

  More +
• Keywords:
  Antibiotic Shortage Antibiotic Stewardship
• Source:
  Infect Control Hosp Epidemiol. 38(3):356-359
• Pubmed ID:
  27917734
• Pubmed Central ID:
  PMC8011860
• Document Type:
  Journal Article
• Funding:
  U54 CK000609/CK/NCEZID CDC HHSUnited States/ ; KL2 TR002346/TR/NCATS NIH HHSUnited States/ ; U54 CK000482/CK/NCEZID CDC HHSUnited States/ ; KL2 TR000450/TR/NCATS NIH HHSUnited States/ ; L30 AI133778/AI/NIAID NIH HHSUnited States/ ; U54CK000482/ACL/ACL HHSUnited States/
• Place as Subject:
  Missouri
• Volume:
  38
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:dcd9df8055533e88d6f229ca356cd31a07bbbd0fc2c5abd22505324fe3f9ac45
• Download URL:
  https://stacks.cdc.gov/view/cdc/104636/cdc_104636_DS1.pdf
• File Type:
  [PDF - 492.41 KB ]