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Toxicological profile for 1,1,2-trichloroethane
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March 2021
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[PDF-2.68 MB]
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Description:1,1,2-Trichloroethane (CASRN 79-00-5) is predominantly a man-made chemical whose presence in the environment results from anthropogenic activity. This chemical is an intermediate in the biodegradation of 1,1,2,2-tetrachloroethane. It is made commercially by the chlorination of ethylene with chlorine or by the oxychlorination of ethylene with hydrogen chloride (HCl) and oxygen. It is primarily used as a captive intermediate in the production of 1,1-dichloroethene (vinylidene chloride), but may also be used as a solvent, especially in chlorinated rubber manufacture but also for fats, oils, waxes, and resins (Hawley 1981).
1,1,2-Trichloroethane is released into the air by vent gas and fugitive emissions from the production and use of 1,1,2-trichloroethane as well as volatilization from waste water and municipal treatment plants. Although 1,1,2-trichloroethane is found in the effluent from laundries and organic chemicals and mechanical products industries, exposure to 1,1,2-trichloroethane from contaminated drinking water is uncommon (Westrick et al. 1984). Few data with respect to the release of 1,1,2-trichloroethane to soil are available, but these releases are expected to involve the landfilling of sludge and process residues.
Version History
Date Description
March 2021 Final toxicological profile released
December 2019 Draft for public comment toxicological profile released
December 2010 Addendum to the toxicological profile released
December 1989 Final toxicological profile released
CS274127-A
tp148.pdf
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