Prevalence, Risk Factors, and Trajectories of Sleep Disturbance in a Cohort of African American Breast Cancer Survivors

Details

• Alternative Title:
  Support Care Cancer
• Personal Author:
  Gonzalez, Brian D. ; Eisel, Sarah L. ; Qin, Bo ; Llanos, Adana A.M. ; Savard, Josée ; Hoogland, Aasha I. ; Jim, Heather ; Lin, Yong ; Demissie, Kitaw ; Hong, Chi-Chen ; Bandera, Elisa V.
• Description:
  Purpose:
  
  Sleep disturbance may be an overlooked modifiable risk factor for health disparities among African American breast cancer survivors (AABCS). This study aimed to identify the prevalence of and risk factors for sleep disturbance in a cohort of AABCS.
  
  Methods:
  
  The study was conducted among participants in the Women’s Circle of Health Follow-up Study, a longitudinal study of breast cancer in 10 counties in New Jersey. Cases were identified shortly after diagnosis by the New Jersey State Cancer Registry. Self-reported sleep disturbance (Pittsburgh Sleep Quality Index) and other factors (e.g., socioeconomic status, menopausal status) were assessed at pre-diagnosis (n=637), 10 months post-diagnosis (n=261), and 24 months post-diagnosis (n=632). Clinical data were obtained via medical record abstraction, and height and weight were measured by study staff.
  
  Results:
  
  Most AABCS (57%) reported clinically-significant sleep disturbance before diagnosis, and this rate remained largely unchanged at 10 months (53%) and 24 months post-diagnosis (61%). Average sleep disturbance scores indicated clinically-significant disturbance at all three assessments (M range=6.67–7.57). Most reported sleeping fewer than the recommended 7 hours per night at each assessment (range 57%–65%). Risk factors for sleep disturbance were identified at each assessment, including pre-diagnosis (less education), 10 months post-diagnosis (lack of insurance, treatment with chemotherapy), and 24 months post-diagnosis (younger age, less education, lower income, obesity, and lymphedema). Treatment with endocrine therapy was a protective factor at 10 months post-diagnosis.
  
  Conclusion:
  
  Most AABCS report clinically-significant sleep disturbance from before diagnosis through 24 months post-diagnosis. These rates appear indicate AABCS experience significant sleep-related disparities.
  
  
• Subjects:
  Adult Aged Black Or African American Cancer Survivors Cohort Studies Female Follow-Up Studies Humans Longitudinal Studies Middle Aged Prevalence Risk Factors Sleep Wake Disorders Survivors Young Adult

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• Source:
  Support Care Cancer. 29(5):2761-2770
• Pubmed ID:
  32995999
• Pubmed Central ID:
  PMC7981240
• Document Type:
  Journal Article
• Funding:
  U58 DP003931/DP/NCCDPHP CDC HHSUnited States/ ; K01 CA193527/CA/NCI NIH HHSUnited States/ ; P30 CA016056/CA/NCI NIH HHSUnited States/ ; R00 MD013300/MD/NIMHD NIH HHSUnited States/ ; R25 CA090314/CA/NCI NIH HHSUnited States/ ; K99 MD013300/MD/NIMHD NIH HHSUnited States/ ; HHSN261201300021C/CA/NCI NIH HHSUnited States/ ; NU5U58DP003931-05-00/CC/CDC HHSUnited States/ ; K01 CA211789/CA/NCI NIH HHSUnited States/ ; K99 MD013300/CA/NCI NIH HHSUnited States/ ; R01 CA185623/CA/NCI NIH HHSUnited States/ ; P30 CA072720/CA/NCI NIH HHSUnited States/ ; R25 HL105444/HL/NHLBI NIH HHSUnited States/ ; P01 CA151135/CA/NCI NIH HHSUnited States/ ; R01 CA185623S1/National Cancer Institute (US)/ ; HHSN261201300021I/CA/NCI NIH HHSUnited States/ ; P30 CA072720-5929/National Cancer Institute (US)/
• Volume:
  29
• Issue:
  5
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:5edc30059ffde7724a65ea57b12f784e9f70b0e711e2f662d8f92ac5435e3288
• Download URL:
  https://stacks.cdc.gov/view/cdc/104377/cdc_104377_DS1.pdf
• File Type:
  [PDF - 546.76 KB ]