Why CDC measures vaccine effectiveness
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Mar 9, 2021
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Description:Updated Mar. 9, 2021
After the U.S. Food and Drug Administration (FDA) approves a vaccine or authorizes a vaccine for emergency use, experts continue to assess vaccine effectiveness—or how a vaccine works in real-world conditions. The goal is to understand how a vaccine protects people outside of strict clinical trial settings.
CDC and other partners will continue to assess how COVID-19 vaccines work in real-world conditions. Assessing how vaccines work in the real-world is important to:
• Learn if vaccines offer the same protection seen in clinical trials.
• Adjust vaccine recommendations, as needed.
• Learn why and how often breakthrough cases (people getting sick after vaccination) occur.
• Learn how vaccines protect against COVID-19 variants.
• Inform vaccine policy and widespread vaccine distribution.
• Inform future development of improved vaccine technologies.
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