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Up-to-date Information: Up-to-Date Info : To find the latest CDC information on this topic go to: https://www.cdc.gov/coronavirus/2019-nCoV/index.html

Why CDC measures vaccine effectiveness

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  • Description:
    Updated Mar. 9, 2021

    After the U.S. Food and Drug Administration (FDA) approves a vaccine or authorizes a vaccine for emergency use, experts continue to assess vaccine effectiveness—or how a vaccine works in real-world conditions. The goal is to understand how a vaccine protects people outside of strict clinical trial settings.

    CDC and other partners will continue to assess how COVID-19 vaccines work in real-world conditions. Assessing how vaccines work in the real-world is important to:

    • Learn if vaccines offer the same protection seen in clinical trials.

    • Adjust vaccine recommendations, as needed.

    • Learn why and how often breakthrough cases (people getting sick after vaccination) occur.

    • Learn how vaccines protect against COVID-19 variants.

    • Inform vaccine policy and widespread vaccine distribution.

    • Inform future development of improved vaccine technologies.

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