The path to the standardization of PTH: Is this a realistic possibility? a position paper of the IFCC C-BM

Cavalier, Etienne; Vasikaran, Samuel; Bhattoa, Harjit P.; Heijboer, Annemieke C.; Makris, Konstantinos; Ulmer, Candice Z.

doi:10.1016/j.cca.2020.12.022

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The path to the standardization of PTH: Is this a realistic possibility? a position paper of the IFCC C-BM

4 2021
By Cavalier, Etienne ; Vasikaran, Samuel ; Bhattoa, Harjit P. ; ...
http://dx.doi.org/10.1016/j.cca.2020.12.022
Source: Clin Chim Acta. 515:44-51

[PDF-429.81 KB]

English

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Details:

Alternative Title:

Clin Chim Acta
Personal Author:

Cavalier, Etienne ; Vasikaran, Samuel ; Bhattoa, Harjit P. ; Heijboer, Annemieke C. ; Makris, Konstantinos ; ... More +

Cavalier, Etienne ; Vasikaran, Samuel ; Bhattoa, Harjit P. ; Heijboer, Annemieke C. ; Makris, Konstantinos ; Ulmer, Candice Z. Less -
Description:

Parathyroid hormone (PTH) determination is of greatest importance for patients suffering from parathyroid gland disorders and for the follow-up of bone turnover in patients suffering from chronic kidney disease (CKD). Two generations of PTH assays are simultaneously present on the market for PTH quantification. As these assays are not yet standardized, this results in a significant level of confusion in the care of CKD patients. One key objective of the IFCC Committee for Bone Metabolism is to improve this situation. In this position paper, we will highlight the current state of PTH testing and propose a pathway to ultimately overcome issues resulting from PTH assay variability.
Subjects:

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Humans Immunoassay Kidney Failure, Chronic Parathyroid Hormone Reference Standards Renal Insufficiency, Chronic
Keywords:

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Immunoassays Parathyroid Hormone Standardization
Source:

Clin Chim Acta. 515:44-51
Pubmed ID:

33412144
Pubmed Central ID:

PMC7920929
Document Type:

Journal Article
Funding:

CC999999/ImCDC/Intramural CDC HHSUnited States/
Collection(s):

CDC Public Access
Main Document Checksum:

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urn:sha-512:51964b1c249f376ae2e367e64783d1190ea3fa015c94b41273996ae4c91f8c8e0e4d5ac98c91c552e4ea6eab1b4302da7345caf5e3e492da661c6d4b9c12b003
Download URL:

https://stacks.cdc.gov/view/cdc/103808/cdc_103808_DS1.pdf
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