A comparison of general, genitourinary, bowel, and sexual quality of life among long term survivors of prostate, bladder, colorectal, and lung cancer

Details

• Alternative Title:
  J Geriatr Oncol
• Personal Author:
  Ramsey, Scott D. ; Hall, Ingrid J. ; Smith, Judith Lee ; Ekwueme, Donatus U. ; Fedorenko, Catherine R. ; Kreizenbeck, Karma ; Bansal, Aasthaa ; Thompson, Ian M. ; Penson, David F.
• Description:
  Objectives:
  
  Studies of local stage prostate cancer survivors suggest that treatments carry risk of persistent impotence, incontinence, and bowel dysfunction. To examine impacts of cancer type and side effects on health-related quality of life (HRQoL) in long-term cancer survivorship, we evaluated 5-year follow-up of patients with prostate cancer and compared results with a matched group of male long-term survivors of other local-stage cancers.
  
  Materials and Methods:
  
  We examined genitourinary, bowel and sexual symptoms, and general quality of life. Matched survivors of colorectal, lung, and bladder cancers were recruited via registries in 3 different regions in the United States. Patients were surveyed 3–5 years after diagnosis with the SF-12 and EPIC to evaluate general mental and physical health-related quality of life (HRQoL) and patient function and bother.
  
  Results:
  
  We analyzed responses from long-term prostate (n = 77) and bladder, colorectal, and lung cancer (n = 124) patients. In multivariate analysis, long-term local stage prostate cancer survivors had significantly higher SF-12 physical component scores but did not differ from long-term survivors of other cancers in terms of their SF-12 mental summary scores. Prostate survivors had similar mental, urinary, bowel, and sexual HRQoL compared to long-term survivors of other local stage cancers.
  
  Conclusion:
  
  Long-term general and prostate-specific HRQoL was similar between local stage prostate and bladder, colorectal, and lung patients with cancer. Future research focusing on factors other than initial treatment and the cancer type per se may provide more meaningful information regarding factors that predict disparities on HRQoL among longer-term survivors of early stage male cancers.
  
  
• Subjects:
  Colorectal Neoplasms Humans Lung Neoplasms Male Prostatic Neoplasms Quality Of Life Surveys And Questionnaires Survivors Urinary Bladder
• Keywords:
  Bladder Cancer Colorectal Cancer Local Stage Prostate Lung Cancer Quality Of Life Symptom Burden
• Source:
  J Geriatr Oncol. 12(2):305-311
• Pubmed ID:
  32739353
• Pubmed Central ID:
  PMC7855401
• Document Type:
  Journal Article
• Funding:
  P30 CA015704/CA/NCI NIH HHSUnited States/ ; U48 DP001911/DP/NCCDPHP CDC HHSUnited States/ ; U48 DP000050/DP/NCCDPHP CDC HHSUnited States/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/ ; P30 CA054174/CA/NCI NIH HHSUnited States/
• Volume:
  12
• Issue:
  2
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:3cb32f0ff1776c897c4155f490fb0bcc758eb32f5e2fdabb178bfca8ea3b33eb
• Download URL:
  https://stacks.cdc.gov/view/cdc/102165/cdc_102165_DS1.pdf
• File Type:
  [PDF - 242.67 KB ]