Natural SARS-CoV-2 infections, including virus isolation, among serially tested cats and dogs in households with confirmed human COVID-19 cases in Texas, USA

Details

• Alternative Title:
  bioRxiv
• Personal Author:
  Hamer, Sarah A. ; Pauvolid-Corrêa, Alex ; Zecca, Italo B. ; Davila, Edward ; Auckland, Lisa D. ; Roundy, Christopher M. ; Tang, Wendy ; Torchetti, Mia ; Killian, Mary Lea ; Jenkins-Moore, Melinda ; Mozingo, Katie ; Akpalu, Yao ; Ghai, Ria R. ; Spengler, Jessica R. ; Behravesh, Casey Barton ; Fischer, Rebecca S. B. ; Hamer, Gabriel L.
• Description:
  The natural infections and epidemiological roles of household pets in SARS-CoV-2 transmission are not understood. We conducted a longitudinal study of dogs and cats living with at least one SARS-CoV-2 infected human in Texas and found 47.1% of 17 cats and 15.3% of 59 dogs from 25.6% of 39 households were positive for SARS-CoV-2 via RT-PCR and genome sequencing or neutralizing antibodies. Virus was isolated from one cat. The majority (82.4%) of infected pets were asymptomatic. Re-sampling of one infected cat showed persistence of viral RNA at least 32 d-post human diagnosis (25 d-post initial test). Across 15 antibody-positive animals, titers increased (33.3%), decreased (33.3%) or were stable (33.3%) over time. A One Health approach is informative for prevention and control of SARS-CoV-2 transmission.
• Subjects:
  COVID-19
• Source:
  bioRxiv.
• Pubmed ID:
  33330861
• Pubmed Central ID:
  PMC7743065
• Document Type:
  Journal Article
• Funding:
  K01 AI128005/AI/NIAID NIH HHS/United States
• Place as Subject:
  Texas
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:19400d0dc656d86f8bd5b10a8049fa353cf34bba793b9e9861e63a66bff17d3c
• Download URL:
  https://stacks.cdc.gov/view/cdc/100847/cdc_100847_DS1.pdf
• File Type:
  [PDF - 406.42 KB ]