This collection is a one-stop shop for guidelines or recommendations developed by CDC, CDC working in collaboration with other organizations or agencies, or by CDC federal advisory committees. These documents contain statements that include recommendations, strategies, and/or information that assists decision makers (such as healthcare providers, federal, state or private agencies, employers, public health officials, or the public) in choosing between alternative courses of action in specific situations. Ultimately, these documents are focused on providing actionable steps to address a specific issue of importance to public health.

The topical areas covered include surveillance, investigation, diagnosis, treatment, intervention, prevention, control, and public health preparedness among others for several diseases and conditions.