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Showing 45241 - 45260 of 82972 results
  • Chemical Identification of a Toxicant Leached from a Surgical Drain
    Chemical Identification of a Toxicant Leached from a Surgical Drain
    Depree GJ ;
    Knudsen GA
    2001/07/08 | National Institute for Occupational Safety and Health (NIOSH)
    Residual chemicals can leach from medical devices that contact biological membranes. In repeat studies, when subcutaneously implanted into mice, one brand (Brand A) of latex surgical drain consistently produced acute toxic reactions resulting in mortality within 12 h. This was not found with other brands tested. This abstract describes the methodol ...
    Public Domain
  • A Rat Model for Controlling and Quantifying Voluntary Muscle Performance of Upper Extremities
    A Rat Model for Controlling and Quantifying Voluntary Muscle Performance of Upper Extremities
    Cutlip, Robert G. ;
    Wirth, Oliver
    2001/07/08 | National Institute for Occupational Safety and Health (NIOSH)
    Musculoskeletal disorders (MSDs) are a major health concern of the National Institute for Occupational Safety and Health (NIOSH) and a National Occupational Research Agenda (NORA) priority. Musculoskeletal disorders represent a broad category of injuries and illnesses of the upper and lower extremities. Claims of MSDs in the workplace often are ass ...
    Public Domain
  • Evaluation of the Potential for Dermal Exposure to 3Amino5Mercapto12 4Triazole AMT to Induce Pulmonary Hyperreactivity
    Evaluation of the Potential for Dermal Exposure to 3-Amino-5-Mercapto-1,2, 4-Triazole (AMT) to Induce Pulmonary Hyperreactivity
    Klink KJ ;
    Meade BJ
    2001/07/08 | National Institute for Occupational Safety and Health (NIOSH)
    3-Amino-5-mercapto-1,2,4-triazole (AMT) is an intermediate in the production of the herbicide DE498. Little toxicological information is available for either compound. These studies were conducted, using BALB/c female mice, to evaluate the potential of AMT to cause allergic sensitization and induce pulmonary hyper-reactivity following dermal exposu ...
    Public Domain
  • Effect of Exposure to Diesel Exhaust Particles DEP on Pulmonary Allergic Sensitization
    Effect of Exposure to Diesel Exhaust Particles (DEP) on Pulmonary Allergic Sensitization
    Al-Humadi NH ;
    Barger M
    2001/07/08 | National Institute for Occupational Safety and Health (NIOSH)
    The adjuvant effect of DEP on ovalbumin (OVA) sensitization and its underlying mechanism were studied. Brown Norway rats were exposed to saline or DEP (5 mg kg) on day 1 followed by exposure to OVA (40 mg m3: 30 min) or saline on day 2.8. 15. and 29. Animals were sacrificed and analyzed for inflammatory markers in the lavage fluid, cysteine and glu ...
    Public Domain
  • Alteration of Pulmonary Cytochrome P450 System by Diesel Exhaust Particles
    Alteration of Pulmonary Cytochrome P-450 System by Diesel Exhaust Particles
    Barger MW ;
    Castranova, Vincent
    2001/07/08 | National Institute for Occupational Safety and Health (NIOSH)
    The adverse health effects of diesel exhaust particles (DEP) including genotoxicity have been attributed to absorbed polycyclic aromatic hydrocarbons (PAHs) on the particles. It has been prosposed that these compounds require bioactivation by cytochrome P-450 (CYP) to exert carcinogenicity. The objective of this study was to determine the effect of ...
    Public Domain
  • Octamethylcyclotetrasiloxane Induces Estrogenic Effects in B6C3F1 Mice
    Octamethylcyclotetrasiloxane Induces Estrogenic Effects in B6C3F1 Mice
    He B ;
    Meade J
    2001/07/08 | National Institute for Occupational Safety and Health (NIOSH)
    Octamethylcyclotetrasiloxane (D4) is a low molecular weight silicone which is extensively used in personal care products and foods because of its lubricity, low surface tension, and low heat of vaporization. The estrogenic activity of D4 was evaluated in these studies using both in vitro and in vivo methods. Intact female B6C3F1 mice demonstrated a ...
    Public Domain
  • Development and Use of a HighPressure Packer for Measuring Horizontal Stress Using the Hydraulic Fracturing Method
    Development and Use of a High-Pressure Packer for Measuring Horizontal Stress Using the Hydraulic Fracturing Method
    Oyler, David C.
    2001/07/07 | Mining Publications
    Research conducted by the National Institute for Occupational Safety and Health (NIOSH) has shown that knowledge of the direction and magnitude of the in situ horizontal stress can be critical to the success of many underground mining operations. One technique employed by NIOSH for determining in situ stress has been hydraulic fracturing from boreh ...
    Public Domain
  • Numerical Geomechanical Modeling for the Stillwater Mine Nye Montana
    Numerical Geomechanical Modeling for the Stillwater Mine, Nye, Montana
    Brady, Thomas M. ;
    Langston RB
    2001/07/07 | Mining Publications
    A geomechanical numerical modeling research project is being conducted for the Stillwater Mine located in Nye, Montana. The project involves identifying potential ground control problems and exploring various methods of modeling the behavior of the rock, with objectives of improving underground safety and facilitating optimum support design. During ...
    Public Domain
  • Geomechanics of Large Stone Structures A Case History from the Washington National Cathedral
    Geomechanics of Large Stone Structures: A Case History from the Washington National Cathedral
    Mark C ;
    Mark R
    2001/07/07 | Mining Publications
    The Washington National Cathedral is one of the largest masonry structures in the USA, and like many of its European Gothic counterparts, it required nearly a century to construct. The design was altered during this period, resulting in greater loadings than were originally anticipated on the soil beneath the foundation. When signs of continuing di ...
    Public Domain
  • Application of Particle Flow Code to Evaluate a Concept for Detecting Hazardous Voids in Surge Piles Using Profile Scanning
    Application of Particle Flow Code to Evaluate a Concept for Detecting Hazardous Voids in Surge Piles Using Profile Scanning
    Iverson, Stephen R. ;
    Larson, Mark K.
    2001/07/07 | Mining Publications
    Researchers from the Spokane Research Laboratory of the National Institute for Occupational Safety and Health have used the particle flow code (PFC2D) computer program to determine whether detecting large voids in surge piles is feasible. The method is to determine profile volume - the volume calculated by determining the volume of the top surface ...
    Public Domain
  • Rock mechanics in the national interest
    Rock mechanics in the national interest.
    2001/07/07 | Mining Publications
    It is fitting that the theme for this first U.S. Rock Mechanics Symposium to be held in the Nation's capital is "Rock Mechanics in the National Interest." This proceedings volume showcases all aspects of the science and engineering of rock mechanics that spans this broad theme - including many aspects of environmental protection, national security, ...
    Public Domain
  • Mining the Remaining Portion of the Ross Shaft Pillar
    Mining the Remaining Portion of the Ross Shaft Pillar
    Brady, Thomas M. ;
    Johnson JC
    2001/07/07 | Mining Publications
    Past finite element analysis of pillar mining effects on the Ross Shaft at the Homestake Mine in Lead, South Dakota, indicated stability of the shaft during mining on both sides of a central pillar that was defined within a much larger original shaft pillar. Experience with pillar mining that began in 1988 verified the earlier forecast of stability ...
    Public Domain
  • Rock Damage Characterisation from Microseismic Monitoring
    Rock Damage Characterisation from Microseismic Monitoring
    Gale, Winton J. ;
    Hatherly P
    2001/07/07 | Mining Publications
    This paper outlines the concepts used to correlate rock failure with microseismic events and presents examples of microseismic monitoring together with associated computer modeling of the rock failure. This study is motivated by the need to develop improved ways to reduce ground control hazards in underground mining. Toward this end we present and ...
    Public Domain
  • Development of Stress Measurements and Instrument Placement Techniques for Longwall Coal
    Development of Stress Measurements and Instrument Placement Techniques for Longwall Coal
    Chen J ;
    Dunford, John P.
    2001/07/07 | Mining Publications
    Western coal mines are operating under increasingly challenging ground conditions. Researchers at the Spokane Research Laboratory of the National Institute for Occupational Safety and Health are cooperating with mines to evaluate how these conditions affect mine operating stability and related miner safety. A system was developed to monitor rock an ...
    Public Domain
  • Case Studies of Cable Bolts Using Instrumented King Wires
    Case Studies of Cable Bolts Using Instrumented King Wires
    Curtin RP ;
    Martin LA
    2001/07/07 | Mining Publications
    Instrumented cable bolts developed at the Spokane Research Laboratory of the National Institute for Occupational Safety and Health were used in conjunction with existing ground control to monitor rock mass loads at various field sites (FMC Granger, Getchell, Meikle, SSX, K-2, and Stillwater). Axial and shear loads were determined by strain gauges t ...
    Public Domain
  • Three Dimensional Microseismic Monitoring of a Utah Longwall
    Three Dimensional Microseismic Monitoring of a Utah Longwall
    Ellenberger, John L. ;
    Heasley, Keith A.
    2001/07/07 | Mining Publications
    The National Institute for Occupational Safety and Health (NIOSH) has continued the research role of the former US Bureau of Mines (USBM) to engineer techniques that will reduce the hazards in the mining work place associated with coal bumps. Recent research focused on a longwall coal mine in Utah with overburden greater than 750 m (2,500 ft) conta ...
    Public Domain
  • A Method for Modeling Variation of In Situ Stress Related to Lithology
    A Method for Modeling Variation of In Situ Stress Related to Lithology
    Whyatt, Jeffrey K.
    2001/07/07 | Mining Publications
    Assuring ground control safety in many mining and tunneling projects depends, at least in part, on an understanding of in situ stress conditions that will be encountered. Yet it is rarely practical to conduct more than a very limited number of stress measurements. Stresses along the route of a proposed excavation are typically interpolated from ava ...
    Public Domain
  • Emerging Technologies and the Future of Geotechnical Instrumentation
    Emerging Technologies and the Future of Geotechnical Instrumentation
    Girard, Jami M. ;
    McHugh EL
    2001/07/07 | Mining Publications
    This paper discusses the results of two recent case studies in which high-tech prototype instruments were used. The first case study describes the results of a ground-based hyperspectral imaging tool used to map the geology of an open-pit mine highwall. The second case study outlines the use of interferometric synthetic aperture radar and how this ...
    Public Domain
  • Reactivity of Hydroxyl Radicals on Hydroxylated Quartz Surface 1 Cluster Model Calculations
    Reactivity of Hydroxyl Radicals on Hydroxylated Quartz Surface. 1. Cluster Model Calculations
    Konecny R
    2001/07/05 | National Institute for Occupational Safety and Health (NIOSH)
    The interaction of a hydroxyl radical with cluster models of a hydroxylated -quartz surface was studied by means of density functional calculations. Two molecular models representing isolated (Si-OH) and geminal (=Si(OH)2) silanol-terminated quartz surfaces were used. Two reactive sites of the silanol models were investigated: the hydrogen of the s ...
    Public Domain
  • Methodological Issues of Using Observational Human Data in Lung Dosimetry Models for Particulates
    Methodological Issues of Using Observational Human Data in Lung Dosimetry Models for Particulates
    Bailer AJ ;
    Dankovic, David A.
    2001/07/02 | National Institute for Occupational Safety and Health (NIOSH)
    The use of human data to calibrate and validate a physiologically based pharmacokinetic (PBPK) model has the clear advantage of pertaining to the species of interest, namely humans. A challenge in using these data is their often sparse, heterogeneous nature, which may require special methods. Approaches for evaluating sources of variability and unc ...
    Public Domain
45241 - 45260 / 82972