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Guidelines and Recommendations
CDC Guidelines and Recommendations are updated by various CDC centers and institutes in response to new scientific discoveries, to public health issues, and to disease outbreaks. Items in this collection may have been superceded or replaced. For the most up to date information, please visit the CDC home page at https://www.cdc.gov/ and search the Health Topic or Outbreak you are interested in.
2025/09/18
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Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
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Centers for Disease Control and Prevention (U.S.)
Abstract: In 2023, approximately 39,000 persons received a diagnosis of HIV in the United States. Although HIV preexposure prophylaxis (PrEP) is highly effective in preventing HIV infection, acceptance of, adherence to, and persistence taking the available oral and injectable PrEP regimens have been suboptimal. CDC PrEP guidelines published in 2021
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Supporting FilesPublic Domain
Patel, Rupa R. et al. (2025). Clinical Recommendations for the Use of Injectable Lenacapavir as HIV Preexposure — United States, 2025. Morbidity and Mortality Weekly Report (MMWR). 74(35).
Patel, Rupa R. et al. "Clinical Recommendations for the Use of Injectable Lenacapavir as HIV Preexposure — United States, 2025" Morbidity and Mortality Weekly Report (MMWR) 74, no. 35 (2025)
Patel, Rupa R. et al. "Clinical Recommendations for the Use of Injectable Lenacapavir as HIV Preexposure — United States, 2025" Morbidity and Mortality Weekly Report (MMWR), vol. 74, no. 35, 2025
2025/09/15
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National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
Abstract: These guidelines update the 2013 “Updated US Public Health Service (PHS) Guidelines for the Management of Occupational Exposures to Human Immunodeficiency Virus and Recommendations for Postexposure Prophylaxis,” hereafter referred to as the 2013 PHS Guidelines.1,2 The availability of new medication options, new information on the window o
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CurrentSupporting FilesPublic Domain
Kofman, Aaron D. et al. (2025). 2025 US Public Health Service Guidelines for the Management of Occupational Exposures to Human Immunodeficiency Virus and Recommendations for Post-exposure Prophylaxis in Healthcare Settings. Infection Control & Hospital Epidemiology. https://doi.org/10.1017/ice.2025.10254
Kofman, Aaron D. et al. "2025 US Public Health Service Guidelines for the Management of Occupational Exposures to Human Immunodeficiency Virus and Recommendations for Post-exposure Prophylaxis in Healthcare Settings" Infection Control & Hospital Epidemiology (2025), https://doi.org/10.1017/ice.2025.10254
Kofman, Aaron D. et al. "2025 US Public Health Service Guidelines for the Management of Occupational Exposures to Human Immunodeficiency Virus and Recommendations for Post-exposure Prophylaxis in Healthcare Settings" Infection Control & Hospital Epidemiology, , 2025, https://doi.org/10.1017/ice.2025.10254
United States. Department of Health and Human Services (HHS). Office of the General Counsel (OGC)
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2025/07/28
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Office of the General Counsel (OGC)
This Manuscript Cover Sheet form should be included with manuscript submissions in support of the CDC Public Access Policy.Please Note: This cover sheet undergoes periodic review and update. The most recent update occurred in July, 2025.
CurrentPublic Domain
United States. Department of Health and Human Services (HHS). Office of the General Counsel (OGC) (2025). CDC Publishing Agreement and Manuscript Cover Sheet [Updated 2025-07-28]. https://dx.doi.org/10.15620/cdc/162073
United States. Department of Health and Human Services (HHS). Office of the General Counsel (OGC) "CDC Publishing Agreement and Manuscript Cover Sheet [Updated 2025-07-28]" (2025), https://dx.doi.org/10.15620/cdc/162073
United States. Department of Health and Human Services (HHS). Office of the General Counsel (OGC) "CDC Publishing Agreement and Manuscript Cover Sheet [Updated 2025-07-28]" , 2025, https://dx.doi.org/10.15620/cdc/162073
2025/05/08
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Recommendations and Reports: Morbidity and Mortality Weekly Report (MMWR)
Nonoccupational postexposure prophylaxis (nPEP) for HIV is recommended when a nonoccupational (e.g., sexual, needle, or other) exposure to nonintact skin or mucous membranes that presents a substantial risk for HIV transmission has occurred, and the source has HIV without sustained viral suppression or their viral suppression information is not kno
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Supporting FilesPublic Domain
Tanner, Mary R. et al. (2025). Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports / Vol. 74 / No. 1, May 8, 2025. Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports. 74(1).
Tanner, Mary R. et al. "Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports / Vol. 74 / No. 1, May 8, 2025" Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports 74, no. 1 (2025)
Tanner, Mary R. et al. "Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports / Vol. 74 / No. 1, May 8, 2025" Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports, vol. 74, no. 1, 2025
National Institute for Occupational Safety and Health
2025/01/01
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NIOSH Numbered Publications
This National Institute for Occupational Safety and Health (NIOSH) policy update for determining the attenuation of hearing protection devices "Individual Fit-Testing Recommendation for Hearing Protection Devices" supersedes the hearing protector derating guidance contained in Chapter 1 (Section 1.5) and Chapter 6 of NIOSH's 1998 Criteria for a Rec
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Supporting FilesPublic Domain
National Institute for Occupational Safety and Health (2025). NIOSH Science Policy Update: Individual Fit-Testing Recommendation for Hearing Protection Devices [2025]. National Institute for Occupational Safety and Health. https://doi.org/10.26616/NIOSHPUB2025104
National Institute for Occupational Safety and Health "NIOSH Science Policy Update: Individual Fit-Testing Recommendation for Hearing Protection Devices [2025]" National Institute for Occupational Safety and Health (2025), https://doi.org/10.26616/NIOSHPUB2025104
National Institute for Occupational Safety and Health "NIOSH Science Policy Update: Individual Fit-Testing Recommendation for Hearing Protection Devices [2025]" National Institute for Occupational Safety and Health, , 2025, https://doi.org/10.26616/NIOSHPUB2025104
August 8, 2024
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Recommendations and Reports: Morbidity and Mortality Weekly Report (MMWR)
The 2024 U.S. Selected Practice Recommendations for Contraceptive Use (U.S. SPR) addresses a selected group of common, yet sometimes complex, issues regarding initiation and use of specific contraceptive methods. These recommendations for health care providers were updated by CDC after review of the scientific evidence and a meeting with national e
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CurrentSupporting FilesPublic Domain
Curtis, Kathryn M. et al. (2024). Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports / Vol. 73 / No. 3, August 8, 2024. Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports. 73(3). http://dx.doi.org/10.15585/mmwr.rr7303a1
Curtis, Kathryn M. et al. "Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports / Vol. 73 / No. 3, August 8, 2024" Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports 73, no. 3 (2024), http://dx.doi.org/10.15585/mmwr.rr7303a1
Curtis, Kathryn M. et al. "Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports / Vol. 73 / No. 3, August 8, 2024" Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports, vol. 73, no. 3, 2024, http://dx.doi.org/10.15585/mmwr.rr7303a1
2024/08/08
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Recommendations and Reports: Morbidity and Mortality Weekly Report (MMWR)
The 2024 U.S. Medical Eligibility Criteria for Contraceptive Use (U.S. MEC) comprises recommendations for the use of specific contraceptive methods by persons who have certain characteristics or medical conditions. These recommendations for health care providers were updated by CDC after review of the scientific evidence and a meeting with national
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CurrentSupporting FilesPublic Domain
Nguyen, Antoinette T. et al. (2024). Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports / Vol. 73 / No. 4, August 8, 2024. Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports. 73(4). http://dx.doi.org/10.15585/mmwr.rr7304a1
Nguyen, Antoinette T. et al. "Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports / Vol. 73 / No. 4, August 8, 2024" Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports 73, no. 4 (2024), http://dx.doi.org/10.15585/mmwr.rr7304a1
Nguyen, Antoinette T. et al. "Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports / Vol. 73 / No. 4, August 8, 2024" Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports, vol. 73, no. 4, 2024, http://dx.doi.org/10.15585/mmwr.rr7304a1
08/09/2023
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Am J Med Qual. 2023 Sep-Oct;38(5S Suppl 2):S12-S34.
cdc:133620
Supporting FilesPublic Domain
Centers for Disease Control and Prevention (U.S.) (2023). SUPPLEMENTARY TABLES. An Integrated Process for Co-Developing and Implementing Written and Computable Clinical Practice Guidelines.
Centers for Disease Control and Prevention (U.S.) "SUPPLEMENTARY TABLES. An Integrated Process for Co-Developing and Implementing Written and Computable Clinical Practice Guidelines" (2023)
Centers for Disease Control and Prevention (U.S.) "SUPPLEMENTARY TABLES. An Integrated Process for Co-Developing and Implementing Written and Computable Clinical Practice Guidelines" , 2023
08/09/2023
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Am J Med Qual. 2023 Sep-Oct;38(5S Suppl 2):S12-S34.
cdc:133620
Supporting FilesPublic Domain
Centers for Disease Control and Prevention (U.S.) (2023). SUPPLEMENTARY TABLES. Adapting Clinical Guidelines for the Digital Age (ACG) Integrated Process and Evaluation Project Plan Template.
Centers for Disease Control and Prevention (U.S.) "SUPPLEMENTARY TABLES. Adapting Clinical Guidelines for the Digital Age (ACG) Integrated Process and Evaluation Project Plan Template" (2023)
Centers for Disease Control and Prevention (U.S.) "SUPPLEMENTARY TABLES. Adapting Clinical Guidelines for the Digital Age (ACG) Integrated Process and Evaluation Project Plan Template" , 2023
08/09/2023
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Am J Med Qual. 2023 Sep-Oct;38(5S Suppl 2):S12-S34.
cdc:133620
Supporting FilesPublic Domain
Centers for Disease Control and Prevention (U.S.) (2023). SUPPLEMENTARY TOOL Part 1 and 2. An Evaluation Framework for a Novel Process to Codevelop Written and Computable Guidelines.
Centers for Disease Control and Prevention (U.S.) "SUPPLEMENTARY TOOL Part 1 and 2. An Evaluation Framework for a Novel Process to Codevelop Written and Computable Guidelines" (2023)
Centers for Disease Control and Prevention (U.S.) "SUPPLEMENTARY TOOL Part 1 and 2. An Evaluation Framework for a Novel Process to Codevelop Written and Computable Guidelines" , 2023
08/09/2023
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Am J Med Qual. 2023 Sep-Oct;38(5S Suppl 2):S12-S34.
Supplementary in-depth evaluation tool for guidelines. For an overall evaluation tool, visit: https://stacks.cdc.gov/view/cdc/132419
Supporting FilesPublic Domain
Centers for Disease Control and Prevention (U.S.) (2023). SUPPLEMENTARY TOOL. An Evaluation Framework for a Novel Process to Codevelop Written and Computable Guidelines.
Centers for Disease Control and Prevention (U.S.) "SUPPLEMENTARY TOOL. An Evaluation Framework for a Novel Process to Codevelop Written and Computable Guidelines" (2023)
Centers for Disease Control and Prevention (U.S.) "SUPPLEMENTARY TOOL. An Evaluation Framework for a Novel Process to Codevelop Written and Computable Guidelines" , 2023
A CDC guideline document contains recommendations for practice that carries the authority of the Agency. To strengthen the process for developing CDC guidelines, the Office of Science (OS), Office of Science Quality (OSQ), Guidelines and Recommendations Team has updated the CDC Guideline Development Decision Tool (GDDT).
CurrentPublic Domain
Dyann Matson Koffman et al. (2021). CDC Guideline Development Decision Tool.
Dyann Matson Koffman and Randy Elder and Vilma Carande-Kulis "CDC Guideline Development Decision Tool" (2021)
Dyann Matson Koffman et al. "CDC Guideline Development Decision Tool" , 2021
2021/12/01
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National Center for HIV, Viral Hepatitis, STD, and TB Prevention (NCHHSTP)
The Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update – A Clinical Practice Guideline includes revisions to several sections. These revisions are intended to update existing guidance using the current evidence base, to incorporate recent FDA PrEP medication approvals, and to clarify specific aspects of c
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Public Domain
United States. Public Health Service (2021). Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update: A Clinical Practice Guideline.
United States. Public Health Service "Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update: A Clinical Practice Guideline" (2021)
United States. Public Health Service "Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update: A Clinical Practice Guideline" , 2021
2021/11/01
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National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP)
The Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2014 Clinical Providers’ Supplement was published in an electronic format in July 2014 so that it could be updated as relevant changes in supporting evidence became available. The Preexposure Prophylaxis for the Prevention of HIV Infection in the United States –
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Public Domain
United States. Public Health Service. (2021). Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update Clinical Providers’ Supplement.
United States. Public Health Service. "Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update Clinical Providers’ Supplement" (2021)
United States. Public Health Service. "Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update Clinical Providers’ Supplement" , 2021
Международные медико-санитарные правила (ММСП, 2005 г.) требуют создания в разных странах необходимого потенциала для борьбы со вспышками заболеваний, включая возможности быстрого реагирования. Группы быстрого реагирования в области общественного здравоохранения (RRT) – это многопрофильные группы обученных и экипированных сотрудников для быстрого р
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CurrentMulti-LanguagePublic Domain
Greiner, Ashley et al. (2020). РУКОВОДСТВО ДЛЯ СОТРУДНИКОВ ЦЕНТРОВ США ПО КОНТРОЛЮ И ПРОФИЛАКТИКЕ заболеваний по созданию и управлению группами быстрого реагирования в сфере общественного ЗДРАВООХРАНЕНИЯ НА ВСПЫШКИ ЗАБОЛЕВАНИЙ.
Greiner, Ashley and Stehling-Ariza, Tasha and Hoffman, Adela "РУКОВОДСТВО ДЛЯ СОТРУДНИКОВ ЦЕНТРОВ США ПО КОНТРОЛЮ И ПРОФИЛАКТИКЕ заболеваний по созданию и управлению группами быстрого реагирования в сфере общественного ЗДРАВООХРАНЕНИЯ НА ВСПЫШКИ ЗАБОЛЕВАНИЙ" (2020)
Greiner, Ashley et al. "РУКОВОДСТВО ДЛЯ СОТРУДНИКОВ ЦЕНТРОВ США ПО КОНТРОЛЮ И ПРОФИЛАКТИКЕ заболеваний по созданию и управлению группами быстрого реагирования в сфере общественного ЗДРАВООХРАНЕНИЯ НА ВСПЫШКИ ЗАБОЛЕВАНИЙ" , 2020
El Reglamento Sanitario Internacional (IHR, por sus siglas en inglés, del 2005) impone la necesidad de que los países establezcan la capacidad para hacer frente a los brotes de enfermedades, incluida la capacidad de responder rápidamente. Los Equipos de Respuesta Rápida (RRT, por sus siglas en inglés) de salud pública son equipos multidisciplinario
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CurrentMulti-LanguagePublic Domain
Greiner, Ashley et al. (2020). Guía para el personal de los Centros para el Control y la Prevención de Enfermedades de los EE. UU. para el establecimiento y gestión de equipos de respuesta rápida de salud pública para brotes de enfermedades.
Greiner, Ashley and Stehling-Ariza, Tasha and Hoffman, Adela "Guía para el personal de los Centros para el Control y la Prevención de Enfermedades de los EE. UU. para el establecimiento y gestión de equipos de respuesta rápida de salud pública para brotes de enfermedades" (2020)
Greiner, Ashley et al. "Guía para el personal de los Centros para el Control y la Prevención de Enfermedades de los EE. UU. para el establecimiento y gestión de equipos de respuesta rápida de salud pública para brotes de enfermedades" , 2020
As Normas Internacionais de Saúde (NIS 2005) prescrevem a obrigação de que os países estabeleçam recursos para surtos de doenças, incluindo a habilidade de resposta rápida. As equipes de resposta emergencial (EREs) são grupos multidisciplinares, treinados e equipados para atender rapidamente a uma emergência de saúde pública em conjunto com uma est
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CurrentMulti-LanguagePublic Domain
Greiner, Ashley et al. (2020). Orientações para os funcionários dos Centros de Controle e Prevenção de Doenças dos Estados Unidos para o estabelecimento e regenciamento de equipes de saúde pública para resposta rápida pública para resposta rápida em surtos de doenças.
Greiner, Ashley and Stehling-Ariza, Tasha and Hoffman, Adela "Orientações para os funcionários dos Centros de Controle e Prevenção de Doenças dos Estados Unidos para o estabelecimento e regenciamento de equipes de saúde pública para resposta rápida pública para resposta rápida em surtos de doenças" (2020)
Greiner, Ashley et al. "Orientações para os funcionários dos Centros de Controle e Prevenção de Doenças dos Estados Unidos para o estabelecimento e regenciamento de equipes de saúde pública para resposta rápida pública para resposta rápida em surtos de doenças" , 2020
تنص اللوائح الصحية الدولية (IHR 2005) على ضرورة قيام الدول بإنشاء قدرة على تفشي الأمراض بما في ذلك القدرة على الاستجابة السريعة. فرق الاستجابة السريعة للصحة العامة (RRTs) هي فرق متعددة التخصصات، مدربة ومجهزة، للنشر السريع في حالة الطوارئ الصحية العامة بالتنسيق مع إطار استجابة طوارئ أكبر. باستخدام نهج متعدد التخصصات، يمكن أن تكون RRTs أصلا رئيسيا ضم
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CurrentMulti-LanguagePublic Domain
Greiner, Ashley et al. (2020). والوقاية منها بالولايات المتحدة الأمريكية لإنشاء وإدارة فرق الاستجابة السريعة التابعة لهيئات الصحة العامة لمواجهة الأمراض المتفشية رشادات لموظفي مراكز مكافحة الأمراض.
Greiner, Ashley and Stehling-Ariza, Tasha and Hoffman, Adela "والوقاية منها بالولايات المتحدة الأمريكية لإنشاء وإدارة فرق الاستجابة السريعة التابعة لهيئات الصحة العامة لمواجهة الأمراض المتفشية رشادات لموظفي مراكز مكافحة الأمراض" (2020)
Greiner, Ashley et al. "والوقاية منها بالولايات المتحدة الأمريكية لإنشاء وإدارة فرق الاستجابة السريعة التابعة لهيئات الصحة العامة لمواجهة الأمراض المتفشية رشادات لموظفي مراكز مكافحة الأمراض" , 2020
The International Health Regulations (IHR 2005) dictate the need for countries to establish disease outbreak capacity including the ability to rapidly respond. Public health rapid response teams (RRTs) are multidisciplinary teams, trained and equipped, to rapidly deploy to a public health emergency in coordination with a larger emergency response f
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CurrentMulti-LanguagePublic Domain
Greiner, Ashley et al. (2020). Guidance for U.S. Centers for Disease Control and Prevention Staff for the Establishment and Management of Public Health Rapid Response Teams for Disease Outbreaks.
Greiner, Ashley and Stehling-Ariza, Tasha and Hoffman, Adela "Guidance for U.S. Centers for Disease Control and Prevention Staff for the Establishment and Management of Public Health Rapid Response Teams for Disease Outbreaks" (2020)
Greiner, Ashley et al. "Guidance for U.S. Centers for Disease Control and Prevention Staff for the Establishment and Management of Public Health Rapid Response Teams for Disease Outbreaks" , 2020
Le Règlement sanitaire international (RSI 2005) dicte la nécessité pour les pays d'établir une capacité de réponse aux épidémies, y compris l'aptitude à intervenir rapidement. Les équipes d'intervention rapide (EIR) en santé publique sont des équipes multidisciplinaires, formées et équipées, qui se déploient rapidement en cas d'urgence de santé pub
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Multi-LanguagePublic Domain
Greiner, Ashley et al. (2020). Directive à l'attention du personnel des Centres pour le Contrôle et la Prévention des Maladies des États-Unis pour la création et la gestion d'équipes de réponse de santé publique rapide pour les épidémies.
Greiner, Ashley and Stehling-Ariza, Tasha and Hoffman, Adela "Directive à l'attention du personnel des Centres pour le Contrôle et la Prévention des Maladies des États-Unis pour la création et la gestion d'équipes de réponse de santé publique rapide pour les épidémies" (2020)
Greiner, Ashley et al. "Directive à l'attention du personnel des Centres pour le Contrôle et la Prévention des Maladies des États-Unis pour la création et la gestion d'équipes de réponse de santé publique rapide pour les épidémies" , 2020
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