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<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" article-type="brief-report"><?properties open_access?><front><journal-meta><journal-id journal-id-type="nlm-ta">MMWR Morb Mortal Wkly Rep</journal-id><journal-id journal-id-type="iso-abbrev">MMWR Morb Mortal Wkly Rep</journal-id><journal-id journal-id-type="publisher-id">WR</journal-id><journal-title-group><journal-title>Morbidity and Mortality Weekly Report</journal-title></journal-title-group><issn pub-type="ppub">0149-2195</issn><issn pub-type="epub">1545-861X</issn><publisher><publisher-name>Centers for Disease Control and Prevention</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">33211682</article-id><article-id pub-id-type="pmc">7676636</article-id><article-id pub-id-type="publisher-id">mm6946a6</article-id><article-id pub-id-type="doi">10.15585/mmwr.mm6946a6</article-id><article-categories><subj-group subj-group-type="heading"><subject>Quick Stats</subject></subj-group></article-categories><title-group><article-title><italic>COVID-19 Stats:</italic> COVID-19 Incidence,* by Urban-Rural Classification<sup>&#x02020;</sup> &#x02014; United States, January 22&#x02013;October 31, 2020<sup>&#x000a7;</sup></article-title></title-group><author-notes><corresp id="cor1"><bold>Reported by:</bold> Lindsey M. Duca, PhD, <email xlink:href="pgz5@cdc.gov">pgz5@cdc.gov</email>; Jayme Coyle, PhD; Carter McCabe, MPH; Catherine A. McLean, MD.</corresp></author-notes><pub-date pub-type="epub"><day>20</day><month>11</month><year>2020</year></pub-date><pub-date pub-type="collection"><day>20</day><month>11</month><year>2020</year></pub-date><volume>69</volume><issue>46</issue><fpage seq="7">1753</fpage><lpage>1753</lpage><permissions><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/3.0/"><license-p>All material in the MMWR Series is in the public domain and may be used and reprinted without permission; citation as to source, however, is appreciated.</license-p></license></permissions></article-meta></front><body><fig id="Fa" fig-type="figure" orientation="portrait" position="float"><caption><p>Early in the pandemic, from mid-March to mid-May, COVID-19 incidence was highest among residents of large central and large fringe metropolitan areas. Beginning in mid-April, incidence in large metropolitan (central and fringe) areas declined and then increased similarly among all urban-rural areas. In September 2020, COVID-19 incidence sharply increased, and it remains highest among residents of medium/small metropolitan areas and micropolitan/noncore areas, indicating increased spread into rural communities. In October, weekly incidence was increasing steadily among all urban-rural areas.</p></caption><graphic xlink:href="mm6946a6-F"/><attrib><bold>Source:</bold> Protect USAFacts. <ext-link ext-link-type="uri" xlink:href="https://usafacts.org/visualizations/coronavirus-covid-19-spread-map/">https://usafacts.org/visualizations/coronavirus-covid-19-spread-map/</ext-link>.</attrib></fig></body><back><fn-group><fn id="FN1"><p><bold>Abbreviation:</bold> COVID-19 = coronavirus disease 2019.</p></fn><fn id="FN2"><label>*</label><p>Incidence = cases per 100,000 population calculated using 2019 U.S. census population.</p></fn><fn id="FN3"><label>&#x02020;</label><p><italic>Large central metro</italic>: counties in metropolitan statistical areas (MSAs) of &#x02265;1 million population that 1) contain the entire population of the largest principal city of the MSA, 2) have the entire population contained in the largest principal city of the MSA, or 3) contain &#x02265;250,000 inhabitants of any principal city of the MSA; <italic>Large fringe metro</italic>: counties in MSAs of &#x02265;1 million population that did not qualify as large central metro counties; <italic>Medium metro</italic>: counties in MSAs of 250,000&#x02013;999,999 population; <italic>Small metro</italic>: counties in MSAs of 50,000&#x02013; 249,999 population; <italic>Micropolitan</italic>: counties centered on an urban cluster with 10,000&#x02013;49,999 population; <italic>Noncore</italic>: nonmetropolitan counties that did not qualify as micropolitan. <ext-link ext-link-type="uri" xlink:href="https://www.cdc.gov/nchs/data_access/urban_rural.htm#2013_Urban-Rural_Classification_Scheme_for_Counties">https://www.cdc.gov/nchs/data_access/urban_rural.htm#2013_Urban-Rural_Classification_Scheme_for_Counties</ext-link>.</p></fn><fn id="FN4"><label>&#x000a7;</label><p>Data are provisional and subject to change.</p></fn></fn-group></back></article>