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<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" article-type="brief-report"><?properties open_access?><front><journal-meta><journal-id journal-id-type="nlm-ta">MMWR Morb Mortal Wkly Rep</journal-id><journal-id journal-id-type="iso-abbrev">MMWR Morb. Mortal. Wkly. Rep</journal-id><journal-id journal-id-type="publisher-id">WR</journal-id><journal-title-group><journal-title>Morbidity and Mortality Weekly Report</journal-title></journal-title-group><issn pub-type="ppub">0149-2195</issn><issn pub-type="epub">1545-861X</issn><publisher><publisher-name>Centers for Disease Control and Prevention</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">32463806</article-id><article-id pub-id-type="pmc">7269608</article-id><article-id pub-id-type="publisher-id">mm6921a4</article-id><article-id pub-id-type="doi">10.15585/mmwr.mm6921a4</article-id><article-categories><subj-group subj-group-type="heading"><subject>Quick Stats</subject></subj-group></article-categories><title-group><article-title>Cancer and Heart Disease Death Rates,<xref ref-type="fn" rid="FN1">*</xref><sup>,</sup><sup><sup>&#x02020;</sup></sup> Among Men and Women Aged 45&#x02013;64 Years &#x02014; United States, 1999&#x02013;2018</article-title></title-group><author-notes><corresp id="cor1"><bold>Reported by: </bold>Sally C. Curtin, MA, <email xlink:href="sac2@cdc.gov">sac2@cdc.gov</email>, 301-458-4142.</corresp></author-notes><pub-date pub-type="epub"><day>29</day><month>5</month><year>2020</year></pub-date><pub-date pub-type="collection"><day>29</day><month>5</month><year>2020</year></pub-date><volume>69</volume><issue>21</issue><fpage seq="5">658</fpage><lpage>658</lpage><permissions><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/3.0/"><license-p>All material in the MMWR Series is in the public domain and may be used and reprinted without permission; citation as to source, however, is appreciated.</license-p></license></permissions></article-meta></front><body><fig id="Fa" fig-type="figure" orientation="portrait" position="float"><caption><p>The cancer death rate for both men and women aged 45&#x02013;64 years declined steadily from 247.0 per 100,000 in 1999 to 194.9 in 2018 for men and from 204.1 to 166.3 for women. The heart disease death rate for men declined from 1999 (235.7) to 2011 (183.5) but then increased to 192.9 in 2018. For women, the heart disease death rate declined from 1999 (96.8) to 2011 (74.9), increased through 2016 (80.3), and then leveled off. In 2018, the cancer death rate for men aged 45&#x02013;64 years was 1% higher than the heart disease death rate; for women, the cancer death rate was approximately twice the heart disease death rate.</p></caption><graphic xlink:href="mm6921a4-F"/><attrib><bold>Source: </bold>National Vital Statistics System, Mortality Data. <ext-link ext-link-type="uri" xlink:href="https://www.cdc.gov/nchs/nvss/deaths.htm">https://www.cdc.gov/nchs/nvss/deaths.htm</ext-link>. </attrib></fig></body><back><fn-group><fn id="FN1"><label>*</label><p>Per 100,000 U.S. population aged 45&#x02013;64 years.</p></fn><fn id="FN2"><p><sup><sup>&#x02020;</sup></sup> Cancer deaths are identified with <italic>International Classification of Diseases, Tenth Edition</italic> codes C00-C97; heart disease deaths are identified with codes I00&#x02013;I09, I11, I13, I20&#x02013;I51.</p></fn></fn-group></back></article>