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Alternative Title:Emerg Infect Dis
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Description:The first coronavirus, avian infectious bronchitis virus, was discovered in 1937 by Fred Beaudette and Charles Hudson. In 1967, June Almeida and David Tyrrell per-formed electron microscopy on specimens from cultures of viruses known to cause colds in humans and identified particles that resembled avian infectious bronchitis virus. Almeida coined the term “coronavirus,” from the Latin corona (“crown”), because the glycoprotein spikes of these viruses created an image similar to a solar corona.Strains that infect humans generally cause mild symp-toms. However, more recently, animal coronaviruses have caused outbreaks of severe respiratory disease in humans, including severe acute respiratory syndrome (SARS), Mid-dle East respiratory syndrome (MERS), and coronavirus disease (COVID-19).
Figure. Illustration reveals the ultrastructural morphology exhibited by coronaviruses. Note the spikes that adorn the outer surface of the virus, which impart the look of a corona surrounding the virion, when viewed electron microscopically. Colorized electron micrograph image: Centers for Disease Control and Prevention/Alissa Eckert, Dan Higgins.
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Pubmed Central ID:PMC7181939
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