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Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus Infections, United States, 2010–11
  • Published Date:
    Feb 2012
  • Source:
    Emerg Infect Dis. 18(2):308-311.
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  1. Characteristics of Patients with Oseltamivir-Resistant Pandemic (H1N1) 2009, United States
    Personal Author:
    Graitcer, Samuel B.; Gubareva, Larisa; Kamimoto, Laurie; Doshi, Saumil; Vandermeer, Meredith; Louie, Janice; Waters, Christine; Moore, Zack; Sleeman, Katrina; Okomo-Adhiambo, Margaret; Marshall, Steven A.; St. George, Kirsten; Pan, Chao-Yang; LaPlante, Jennifer M.; Klimov, Alexander; Fry, Alicia M.;
    Published:
    Feb 2011
    Source:
    Emerg Infect Dis. 17(2):255-257.
    Description:
    During April 2009-June 2010, thirty-seven (0.5%) of 6,740 pandemic (H1N1) 2009 viruses submitted to a US surveillance system were oseltamivir resistant. Most patients with oseltamivir-resistant infections were severely immunocompromised (76%) and had...
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  2. Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus Infection in England and Scotland, 2009–2010
    Personal Author:
    Calatayud, Laurence; Lackenby, Angie; Reynolds, Arlene; McMenamin, Jim; Phin, Nick F.; Zambon, Maria C.; Pebody, Richard;
    Published:
    Oct 2011
    Source:
    Emerg Infect Dis. 17(10):1807-1815.
    Description:
    Oseltamivir has been widely used for pandemic (H1N1) 2009 virus infection, and by April 30, 2010, a total of 285 resistant cases were reported worldwide, including 45 in the United Kingdom. To determine risk factors for emergence of oseltamivir resis...
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  3. Neuraminidase Inhibitor Susceptibility Testing in Human Influenza Viruses: A Laboratory Surveillance Perspective
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    Okomo-Adhiambo, Margaret; Sleeman, Katrina; Ballenger, Kristina; Nguyen, Ha T.; Mishin, Vasiliy P.; Sheu, Tiffany G.; Smagala, James; Li, Yan; Klimov, Alexander I.; Gubareva, Larisa V.;
    Published:
    Oct 13 2010
    Source:
    Viruses. 2010; 2(10):2269-2289.
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    Neuraminidase inhibitors (NAIs) are vital in managing seasonal and pandemic influenza infections. NAI susceptibilities of virus isolates (n = 5540) collected during the 2008-2009 influenza season were assessed in the chemiluminescent neuraminidase in...
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  4. H275Y Mutant Pandemic (H1N1) 2009 Virus in Immunocompromised Patients
    Personal Author:
    Renaud, Christian; Boudreault, Alexandre A.; Kuypers, Jane; Lofy, Kathryn H.; Corey, Lawrence; Boeckh, Michael J.; Englund, Janet A.;
    Published:
    Apr 2011
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    Emerg Infect Dis. 17(4):653-660.
    Description:
    Most oseltamivir-resistant pandemic (H1N1) 2009 viruses have been isolated from immunocompromised patients. To describe the clinical features, treatment, outcomes, and virologic data associated with infection from pandemic (H1N1) 2009 virus with H275...
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  5. Monitoring and Characterization of Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, Japan, 2009–2010
    Personal Author:
    Ujike, Makoto; Ejima, Miho; Anraku, Akane; Shimabukuro, Kozue; Obuchi, Masatsugu; Kishida, Noriko; Hong, Xu; Takashita, Emi; Fujisaki, Seiichiro; Yamashita, Kazuyo; Horikawa, Hiroshi; Kato, Yumiko; Oguchi, Akio; Fujita, Nobuyuki; Tashiro, Masato; Odagiri, Takato;
    Corporate Author:
    Influenza Virus Surveillance Group of Japan
    Published:
    Mar 2011
    Source:
    Emerg Infect Dis. 17(3):470-479.
    Description:
    To monitor and characterize oseltamivir-resistant (OR) pandemic (H1N1) 2009 virus with the H275Y mutation, we analyzed 4,307 clinical specimens from Japan by neuraminidase (NA) sequencing or inhibition assay; 61 OR pandemic (H1N1) 2009 viruses were d...
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