Details:

Alternative Title:
Eur J Contracept Reprod Health Care
Personal Author:
Ti, Angeline ; Curtis, Kathryn M.
Ti, Angeline ; Curtis, Kathryn M. Less -
Description:
Purpose

To evaluate the association between postpartum hormonal contraceptive use and postpartum depression.

Materials and methods

We searched the literature through March 2018 on the association between postpartum hormonal contraception use and incident postpartum depression. We used the United States Preventive Services Task Force framework to assess study quality.

Results

Of 167 articles identified, four met inclusion criteria. Two studies found no differences in rates of postpartum depression between women using postpartum depot medroxyprogesterone and those not using hormonal contraception; however, a study of women receiving injectable norethisterone enanthate immediately postpartum found a 2–3-fold increased risk of depression at six weeks, though not at three months. One study compared combined hormonal contraception, progestin-only pills (POPs), etonogestrel implants and levonorgestrel intrauterine devices (LNG-IUDs) with no hormonal contraception, and found a 35–44% decreased risk of postpartum depression with POPs and LNG-IUDs, a small increased risk of postpartum antidepressant use among women using the etonogestrel implant and vaginal ring, and a decreased risk of antidepressant use with POPs.

Conclusions

Limited evidence found no consistent associations between hormonal contraceptive use and incidence of postpartum depression. Future research would be strengthened by using validated diagnostic measures, careful consideration of confounders, and ensuring adequate follow-up time.


Subjects:
[+]
Adult Article Contraception Contraception Behavior Contraceptives, Oral, Hormonal Depression, Postpartum Female Humans Incidence Postpartum Period Pregnancy Time Factors Young Adult
Source:
Eur J Contracept Reprod Health Care. 24(2):109-116
Pubmed ID:
30920314
Pubmed Central ID:
PMC6541925
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:e0d95851e4745fbe4f75feff265c526b96488d8cce70dfa27d036422068eaccc
Download URL:
https://stacks.cdc.gov/view/cdc/79073/cdc_79073_DS1.pdf
File Type:

Supporting Files

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  	NIHMS1021324-supplement-Supplemental_Material.docx	docx

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