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<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" article-type="research-article"><?properties open_access?><front><journal-meta><journal-id journal-id-type="nlm-ta">MMWR Morb Mortal Wkly Rep</journal-id><journal-id journal-id-type="iso-abbrev">MMWR Morb. Mortal. Wkly. Rep</journal-id><journal-id journal-id-type="publisher-id">WR</journal-id><journal-title-group><journal-title>Morbidity and Mortality Weekly Report</journal-title></journal-title-group><issn pub-type="ppub">0149-2195</issn><issn pub-type="epub">1545-861X</issn><publisher><publisher-name>Centers for Disease Control and Prevention</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">31145717</article-id><article-id pub-id-type="pmc">6542480</article-id><article-id pub-id-type="publisher-id">mm6821a1</article-id><article-id pub-id-type="doi">10.15585/mmwr.mm6821a1</article-id><article-categories><subj-group subj-group-type="heading"><subject>Full Report</subject></subj-group></article-categories><title-group><article-title>Hurricane-Associated Mold Exposures Among Patients at Risk for Invasive Mold Infections After Hurricane Harvey &#x02014; Houston, Texas, 2017</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Chow</surname><given-names>Nancy A.</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Toda</surname><given-names>Mitsuru</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Pennington</surname><given-names>Audrey F.</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Anassi</surname><given-names>Enock</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Atmar</surname><given-names>Robert L.</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff5"><sup>5</sup></xref></contrib><contrib contrib-type="author"><name><surname>Cox-Ganser</surname><given-names>Jean M.</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff6"><sup>6</sup></xref></contrib><contrib contrib-type="author"><name><surname>Da Silva</surname><given-names>Juliana</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="aff" rid="aff7"><sup>7</sup></xref></contrib><contrib contrib-type="author"><name><surname>Garcia</surname><given-names>Bobbiejean</given-names></name><degrees>MPH</degrees><xref ref-type="aff" rid="aff8"><sup>8</sup></xref></contrib><contrib contrib-type="author"><name><surname>Kontoyiannis</surname><given-names>Dimitrios P.</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff9"><sup>9</sup></xref></contrib><contrib contrib-type="author"><name><surname>Ostrosky-Zeichner</surname><given-names>Luis</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff10"><sup>10</sup></xref></contrib><contrib contrib-type="author"><name><surname>Leining</surname><given-names>Lauren M.</given-names></name><degrees>MPH</degrees><xref ref-type="aff" rid="aff5"><sup>5</sup></xref><xref ref-type="aff" rid="aff11"><sup>11</sup></xref></contrib><contrib contrib-type="author"><name><surname>McCarty</surname><given-names>Jennifer</given-names></name><degrees>MPH</degrees><xref ref-type="aff" rid="aff12"><sup>12</sup></xref></contrib><contrib contrib-type="author"><name><surname>Al Mohajer</surname><given-names>Mayar</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff5"><sup>5</sup></xref><xref ref-type="aff" rid="aff12"><sup>12</sup></xref></contrib><contrib contrib-type="author"><name><surname>Murthy</surname><given-names>Bhavini Patel</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="aff" rid="aff13"><sup>13</sup></xref></contrib><contrib contrib-type="author"><name><surname>Park</surname><given-names>Ju-Hyeong</given-names></name><degrees>ScD</degrees><xref ref-type="aff" rid="aff6"><sup>6</sup></xref></contrib><contrib contrib-type="author"><name><surname>Schulte</surname><given-names>Joann</given-names></name><degrees>DO</degrees><xref ref-type="aff" rid="aff14"><sup>14</sup></xref></contrib><contrib contrib-type="author"><name><surname>Shuford</surname><given-names>Jennifer A.</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff8"><sup>8</sup></xref></contrib><contrib contrib-type="author"><name><surname>Skrobarcek</surname><given-names>Kimberly A.</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="aff" rid="aff15"><sup>15</sup></xref></contrib><contrib contrib-type="author"><name><surname>Solomon</surname><given-names>Samantha</given-names></name><xref ref-type="aff" rid="aff16"><sup>16</sup></xref><xref ref-type="aff" rid="aff17"><sup>17</sup></xref></contrib><contrib contrib-type="author"><name><surname>Strysko</surname><given-names>Jonathan</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Chiller</surname><given-names>Tom M.</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Jackson</surname><given-names>Brendan R.</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Chew</surname><given-names>Ginger L.</given-names></name><degrees>ScD</degrees><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Beer</surname><given-names>Karlyn D.</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><aff><target id="aff1" target-type="aff"><sup>1</sup></target>Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, CDC; <target id="aff2" target-type="aff"><sup>2</sup></target>Epidemic Intelligence Service, CDC; <target id="aff3" target-type="aff"><sup>3</sup></target>Division of Environmental Health Science and Practice, National Center for Environmental Health, CDC; <target id="aff4" target-type="aff"><sup>4</sup></target>Harris Health System, Houston, Texas; <target id="aff5" target-type="aff"><sup>5</sup></target>Baylor College of Medicine, Houston, Texas; <target id="aff6" target-type="aff"><sup>6</sup></target>Respiratory Health Division, National Institute for Occupational Safety and Health, CDC; <target id="aff7" target-type="aff"><sup>7</sup></target>Division of Global HIV and Tuberculosis, Center for Global Health, CDC; <target id="aff8" target-type="aff"><sup>8</sup></target>Texas Department of State Health and Services; <target id="aff9" target-type="aff"><sup>9</sup></target>The University of Texas MD Anderson Cancer Center, Houston, Texas; <target id="aff10" target-type="aff"><sup>10</sup></target>McGovern Medical School/Memorial Hermann-Texas Medical Center, Houston Texas; <target id="aff11" target-type="aff"><sup>11</sup></target>UTHealth School of Public Health, Houston, Texas; <target id="aff12" target-type="aff"><sup>12</sup></target>Baylor St. Luke&#x02019;s Medical Center, Houston, Texas; <target id="aff13" target-type="aff"><sup>13</sup></target>Division of State and Local Readiness, Center for Preparedness and Response, CDC; <target id="aff14" target-type="aff"><sup>14</sup></target>Houston Health Department, Houston, Texas; <target id="aff15" target-type="aff"><sup>15</sup></target>Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, CDC; <target id="aff16" target-type="aff"><sup>16</sup></target>Harris County Public Health, Houston, Texas; <target id="aff17" target-type="aff"><sup>17</sup></target>Public Health Associate Program, Center for State, Tribal, Local, and Territorial Support, CDC.</aff></contrib-group><author-notes><corresp id="cor1">Corresponding author: Nancy A. Chow, <email xlink:href="yln3@cdc.gov">yln3@cdc.gov</email>, 404-639-5467.</corresp></author-notes><pub-date pub-type="epub"><day>31</day><month>5</month><year>2019</year></pub-date><pub-date pub-type="collection"><day>31</day><month>5</month><year>2019</year></pub-date><volume>68</volume><issue>21</issue><fpage seq="1">469</fpage><lpage>473</lpage><permissions><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/3.0/"><license-p>All material in the MMWR Series is in the public domain and may be used and reprinted without permission; citation as to source, however, is appreciated.</license-p></license></permissions></article-meta></front><body><p>In August 2017, Hurricane Harvey caused unprecedented flooding and devastation to the Houston metropolitan area (<xref rid="R1" ref-type="bibr"><italic>1</italic></xref>). Mold exposure was a serious concern because investigations after Hurricanes Katrina and Rita (2005) had documented extensive mold growth in flood-damaged homes (<xref rid="R2" ref-type="bibr"><italic>2</italic></xref>,<xref rid="R3" ref-type="bibr"><italic>3</italic></xref>). Because mold exposure can cause serious illnesses known as invasive mold infections (<xref rid="R4" ref-type="bibr"><italic>4</italic></xref>,<xref rid="R5" ref-type="bibr"><italic>5</italic></xref>), and immunosuppressed persons are at high risk for these infections (<xref rid="R6" ref-type="bibr"><italic>6</italic></xref>,<xref rid="R7" ref-type="bibr"><italic>7</italic></xref>), several federal agencies recommend that immunosuppressed persons avoid mold-contaminated sites (<xref rid="R8" ref-type="bibr"><italic>8</italic></xref>,<xref rid="R9" ref-type="bibr"><italic>9</italic></xref>). To assess the extent of exposure to mold and flood-damaged areas among persons at high risk for invasive mold infections after Hurricane Harvey, CDC and Texas health officials conducted a survey among 103 immunosuppressed residents in Houston. Approximately half of the participants (50) engaged in cleanup of mold and water-damaged areas; these activities included heavy cleanup (23), such as removing furniture or removing drywall, or light cleanup (27), such as wiping down walls or retrieving personal items. Among immunosuppressed persons who performed heavy cleanup, 43% reported wearing a respirator, as did 8% who performed light cleanup. One participant reported wearing all personal protective equipment (PPE) recommended for otherwise healthy persons (i.e., respirator, boots, goggles, and gloves). Immunosuppressed residents who are at high risk for invasive mold infections were exposed to mold and flood-damaged areas after Hurricane Harvey; recommendations from health care providers to avoid exposure to mold and flood-damaged areas could mitigate the risk to immunosuppressed persons.</p><p>Interviews were conducted with a convenience sample of immunosuppressed residents from three hospital systems in the Houston metropolitan area. Eligible residents were selected because of risk factors for invasive mold infections (<xref rid="R7" ref-type="bibr"><italic>7</italic></xref>); participants included persons who had received a solid organ transplant in the past year or who had been prescribed an immunosuppressive medication, including tumor necrosis factor inhibitors, cyclosporine, or chemotherapeutic agents, in the last 3 months. Models developed by CDC&#x02019;s Geospatial Research, Analysis and Services Program were used to predict whether residents&#x02019; homes had been flooded. Residents whose homes were predicted to have been flooded were prioritized for contact.</p><p>Among the three hospital systems from which participants were selected, systematic, hospital-wide messaging about avoiding mold exposure had not been disseminated before Hurricane Harvey. A CDC questionnaire developed after Hurricanes Katrina and Rita was modified and field-tested. Questions were focused on experiences with housing, flooding and mold, cleanup activities, and PPE. Cleanup was categorized as either heavy (e.g., removing furniture, drywall, or carpeting) or light (e.g., sweeping, wiping off counters or walls, or retrieving personal items). The 20-minute questionnaire was administered by telephone in either English or Spanish by trained interviewers during October 21&#x02013;November 8, 2017; no personally identifiable information was collected. Interviewers were trained on types of PPE. Federal agency&#x02013;developed materials on how residents who are not immunosuppressed can safely conduct mold cleanup after disasters were made available to participants after the interview. Because this work was part of an ongoing public health response, it was determined to be nonresearch public health practice by CDC&#x02019;s Human Research Protection Office and the local hospitals and thus was not subject to institutional review board review.</p><p>Interviewers attempted to contact 800 immunosuppressed persons, and 167 (21%) were reached, 109 (65%) of whom consented to be interviewed. Among these 109 persons, 103 (94%) had stayed within the Houston metropolitan area during Hurricane Harvey (August 25&#x02013;August 29, 2017) or in the months afterwards (August 30&#x02013;interview date); the survey sample consisted of these 103 persons. During the hurricane, 77 (75%) reported staying at home for the majority of the time, 20 (19%) stayed at friends or relatives&#x02019; homes, and seven (7%) stayed at other places, including hotels, hospitals, shelters, or nursing homes (<xref rid="T1" ref-type="table">Table 1</xref>). In contrast, since the hurricane, 83 (81%) stayed at home, 12 (12%) stayed at friends or relatives&#x02019; homes, and six (6%) stayed at other places. Of the 102 participants whose responses were available, 92 (89%) reported living in their homes at the time of the interview; of the 10 who did not, eight had been back to their homes. One participant&#x02019;s response was not available.</p><table-wrap id="T1" orientation="portrait" position="float"><label>TABLE 1</label><caption><title>Housing status of immunosuppressed survey participants (N = 103) who reported staying in the Houston metropolitan area before or since Hurricane Harvey &#x02014; Houston, Texas, August&#x02013;November 2018</title></caption><table frame="hsides" rules="groups" width="1.732in"><col width="71%" span="1"/><col width="29%" span="1"/><thead><tr><th valign="top" align="left" scope="col" rowspan="1" colspan="1">Housing status</th><th valign="top" align="center" scope="col" rowspan="1" colspan="1">No. (%)</th></tr></thead><tbody><tr><td colspan="2" valign="top" align="left" scope="col" rowspan="1"><bold>During Hurricane Harvey*</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Home<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">77 (75)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Friends or relatives<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">20 (19)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Other<sup>&#x02020;</sup><hr/></td><td valign="top" align="center" rowspan="1" colspan="1">7 (7)<hr/></td></tr><tr><td colspan="2" valign="top" align="left" scope="col" rowspan="1"><bold>Since Hurricane Harvey*</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Home<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">83 (81)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Friends or relatives<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">12 (12)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Other<sup>&#x02020;</sup><hr/></td><td valign="top" align="center" rowspan="1" colspan="1">6 (6)<hr/></td></tr><tr><td colspan="2" valign="top" align="left" scope="col" rowspan="1"><bold>Currently living at home</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Yes<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">92 (89)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">No<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">10 (10)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">&#x000a0;&#x000a0;&#x000a0;Reentered home<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">8 (80)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">&#x000a0;&#x000a0;&#x000a0;Did not reenter home<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">2 (20)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Response not available</td><td valign="top" align="center" rowspan="1" colspan="1">1 (1)</td></tr></tbody></table><table-wrap-foot><p>* Participants might have provided more than one response or provided a response not shown in the options given; thus, the subtotals do not sum to 103.</p><p><bold><sup>&#x02020;</sup></bold> Hospital, hotel, nursing home, or shelter.</p></table-wrap-foot></table-wrap><p>Forty-six (45%) respondents reported that water had entered their homes, 37 (80%) of whom reported that the first floor living space was flooded with a median of 3 inches of water (interquartile range [IQR]&#x000a0;=&#x000a0;1&#x02013;12 inches) for a median of 3 days (IQR&#x000a0;=&#x000a0;1&#x02013;4 days) (<xref rid="T2" ref-type="table">Table 2</xref>). Among the 37 respondents who reported water in their living space, 28 (76%) reported seeing or smelling mold inside the home after the hurricane, and 32 (86%) had their home cleaned for water damage or remediated for mold. Seventeen (53%) participants lived in the house during cleanup, and 17 (53%) performed the cleanup themselves. In addition, 23 (62%) reported plans for cleanup or remediation within the next 6 months.</p><table-wrap id="T2" orientation="portrait" position="float"><label>TABLE 2</label><caption><title>Flooding, mold, and cleanup experiences of immunosuppressed survey respondents who reported water entry into the first floor living space after Hurricane Harvey (N = 37) &#x02014; Houston, Texas, August&#x02013;November 2018</title></caption><table frame="hsides" rules="groups" width="2.445in"><col width="79%" span="1"/><col width="21%" span="1"/><thead><tr><th valign="middle" align="left" scope="col" rowspan="1" colspan="1">Experiences and plans</th><th valign="middle" align="center" scope="col" rowspan="1" colspan="1">No. (%)</th></tr></thead><tbody><tr><td colspan="2" valign="top" align="left" scope="col" rowspan="1"><bold>Saw or smelled mold</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Yes<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">28 (76)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">No<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">8 (22)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Don&#x02019;t know<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">1 (3)<hr/></td></tr><tr><td colspan="2" valign="top" align="left" scope="col" rowspan="1"><bold>Cleaned or remediated home</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Yes<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">32 (86)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">&#x000a0;&#x000a0;&#x000a0;Lived in home during cleanup<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">17 (53)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">&#x000a0;&#x000a0;&#x000a0;Did not live in home during cleanup<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">15 (47)<hr/></td></tr><tr><td colspan="2" valign="top" align="left" scope="col" rowspan="1">&#x000a0;&#x000a0;&#x000a0;Who completed the cleanup*<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">&#x000a0;&#x000a0;&#x000a0;&#x000a0;&#x000a0;&#x000a0;Self<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">17 (53)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">&#x000a0;&#x000a0;&#x000a0;&#x000a0;&#x000a0;&#x000a0;Friends or family<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">12 (38)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">&#x000a0;&#x000a0;&#x000a0;&#x000a0;&#x000a0;&#x000a0;Professional remediation<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">15 (47)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">No<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">5 (14)<hr/></td></tr><tr><td colspan="2" valign="top" align="left" scope="col" rowspan="1"><bold>Plans for cleaning or remediation within 6 mos</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Yes<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">23 (62)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">No<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">11 (30)<hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Don&#x02019;t know</td><td valign="top" align="center" rowspan="1" colspan="1">3 (8)</td></tr></tbody></table><table-wrap-foot><p>* Participants might have provided more than one response; thus, the subtotals do not sum to 32.</p></table-wrap-foot></table-wrap><p>Participation in cleanup activities for any home was assessed among all 103 survey respondents; overall, 50 (49%) engaged in any cleanup activities, including 23 (22%) who engaged in heavy cleanup activities for a median of 7 days (IQR&#x000a0;=&#x000a0;5&#x02013;14 days) and 27 (26%) who participated in only light cleanup activities for a median of 4 days (IQR&#x000a0;=&#x000a0;2&#x02013;14 days) (<xref rid="T3" ref-type="table">Table 3</xref>). Among the 23 participants who engaged in heavy cleanup activities, 10 (43%) wore a full-face, half-face, or N-95 respirator,<xref ref-type="fn" rid="FN1">*</xref> half of whom reported always wearing a respirator during cleanup. Eighteen participants wore gloves during heavy cleanup, eight wore boots, and two wore goggles. Three participants reported using no PPE. Among the 27 participants who engaged in light cleanup activities, two wore a respirator, both of whom reported wearing it at all times during cleanup. Thirteen wore gloves, two used goggles, and one wore boots; seven used no PPE. Among all participants who engaged in cleanup activities, only one wore all PPE recommended for otherwise healthy persons.</p><table-wrap id="T3" orientation="portrait" position="float"><label>TABLE 3</label><caption><title>Time spent in cleanup activities and use of personal protective equipment (PPE) during cleanup among immunosuppressed respondents who stayed in Houston during and after Hurricane Harvey (N = 103) &#x02014; Houston, Texas, August&#x02013;November 2018</title></caption><table frame="hsides" rules="groups" width="4.700in"><col width="49%" span="1"/><col width="17%" span="1"/><col width="17%" span="1"/><col width="17%" span="1"/><thead><tr><th rowspan="3" valign="bottom" align="left" scope="col" colspan="1">Time spent cleaning up and PPE use</th><th valign="bottom" align="center" scope="col" rowspan="1" colspan="1">Heavy cleanup*<hr/></th><th valign="bottom" align="center" scope="col" rowspan="1" colspan="1">Light cleanup<sup>&#x02020;</sup><hr/></th><th valign="bottom" align="center" scope="col" rowspan="1" colspan="1">Total<hr/></th></tr><tr><th valign="bottom" colspan="1" align="center" scope="colgroup" rowspan="1">(n = 23)<hr/></th><th valign="bottom" align="center" scope="col" rowspan="1" colspan="1">(n = 27)<hr/></th><th valign="bottom" align="center" scope="col" rowspan="1" colspan="1">(n = 50)<hr/></th></tr><tr><th valign="bottom" colspan="1" align="center" scope="colgroup" rowspan="1">No. (%)</th><th valign="bottom" align="center" scope="col" rowspan="1" colspan="1">No. (%)</th><th valign="bottom" align="center" scope="col" rowspan="1" colspan="1">No. (%)</th></tr></thead><tbody><tr><td colspan="4" valign="top" align="left" scope="col" rowspan="1"><bold>Hrs per day engaged in cleanup</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">&#x0003c;1<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">0 (0)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">13 (48)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>13 (26)</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">1&#x02013;4<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">8 (35)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">9 (33)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>17 (34)</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">5&#x02013;7<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">9 (39)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">0 (0)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>9 (18)</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">&#x02265;8<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">6 (26)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">5 (19)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>11 (22)</bold><hr/></td></tr><tr><td valign="top" align="left" scope="col" rowspan="1" colspan="1"><bold>Wore a mask<sup>&#x000a7;</sup></bold><hr/></td><td colspan="3" valign="top" align="left" rowspan="1"><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Always<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">5 (22)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">2 (7)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>7 (14)</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Most of the time<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">1 (4)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">0 (0)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>1 (2)</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Less than half of the time<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">4 (17)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">0 (0)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>4 (8)</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">No<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">13 (57)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">23 (85)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>36 (72)</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Missing information<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">0 (0)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">2 (7)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>2 (4)</bold><hr/></td></tr><tr><td colspan="4" valign="top" align="left" scope="col" rowspan="1"><bold>Wore boots</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Yes<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">8 (35)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">1 (4)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>9 (18)</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">No<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">15 (65)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">26 (96)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>41 (82)</bold><hr/></td></tr><tr><td colspan="4" valign="top" align="left" scope="col" rowspan="1"><bold>Wore gloves</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Yes<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">18 (78)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">13 (48)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>31 (62)</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">No<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">5 (22)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">14 (52)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>19 (38)</bold><hr/></td></tr><tr><td colspan="4" valign="top" align="left" scope="col" rowspan="1"><bold>Wore goggles</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Yes<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">2 (9)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">2 (7)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>4 (8)</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">No<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">21 (91)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">25 (93)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>46 (92)</bold><hr/></td></tr><tr><td colspan="4" valign="top" align="left" scope="col" rowspan="1"><bold>Wore any PPE</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">Yes<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">20 (87)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1">20 (74)<hr/></td><td valign="top" align="center" rowspan="1" colspan="1"><bold>40 (80)</bold><hr/></td></tr><tr><td valign="top" align="left" scope="row" rowspan="1" colspan="1">No</td><td valign="top" align="center" rowspan="1" colspan="1">3 (13)</td><td valign="top" align="center" rowspan="1" colspan="1">7 (26)</td><td valign="top" align="center" rowspan="1" colspan="1"><bold>10 (20)</bold></td></tr></tbody></table><table-wrap-foot><p>* For example, removing furniture, drywall, or carpeting.</p><p><bold><sup>&#x02020;</sup></bold> For example, sweeping, wiping off counters or walls, or retrieving personal items.</p><p><sup>&#x000a7;</sup> Mask includes full-face respirator, half-face respirator, or N-95 respirator.</p></table-wrap-foot></table-wrap><p>Among all 103 participants, 62 (60%) reported hearing or reading about what to wear to clean up mold and floodwater. The most commonly reported information sources included television (14), word of mouth (14), and health care providers (seven). No participants reported obtaining information from social media or a website.</p><sec sec-type="discussion"><title>Discussion</title><p>This investigation of mold exposures and PPE use after Hurricane Harvey found that a convenience sample of immunosuppressed adult residents were exposed to mold and water-damaged areas. Immunosuppressed persons are at risk for invasive mold infections (primarily respiratory) with mortality rates as high as 50% (<xref rid="R6" ref-type="bibr"><italic>6</italic></xref>). Although federal agencies recommend that immunosuppressed persons avoid flooded and mold-contaminated buildings (<xref rid="R9" ref-type="bibr"><italic>9</italic></xref>), approximately half of survey participants engaged in cleanup activities, with approximately half of those who engaged in heavy cleanup and most of those engaged in light cleanup reporting not wearing respiratory protection; gloves were the most frequently reported PPE used.</p><p>In disaster settings such as Hurricane Harvey, immunosuppressed residents might experience difficulty in adhering to recommendations about avoiding mold-contaminated sites if the majority of homes in the community are affected. In such cases, proper use of an appropriate respirator and other PPE during reentry to the home might reduce mold exposure.</p><p>No participants reported websites or social media as sources of information about what one should wear during cleanup of mold and floodwater. This could reflect a unique demographic profile in this group; however, the profile could not be assessed because demographic information was not obtained as part of the survey.</p><p>The findings in this report are subject to at least three limitations. First, survey participants were not representative of all immunosuppressed patients in the Houston area because the participants consisted of a convenience sample of patients with specific conditions from three hospital systems. Although these findings cannot be extrapolated to all immunosuppressed residents in the Houston area during and after Hurricane Harvey, they suggest that a substantial number of immunosuppressed persons were exposed to mold and flood-damaged areas and that PPE use among some immunosuppressed persons who engaged in cleanup activities was low. Second, although it was ascertained that the three hospital systems had not conducted systematic, hospital-wide messaging about avoiding mold exposure before Hurricane Harvey, survey participants were not asked whether they had been told by a health care provider to avoid exposure to mold. Thus, it was not possible to determine whether survey participants who were exposed to mold were aware of federal recommendations. Finally, eligibility criteria included immunosuppressive medications for health conditions of varying severity, and information on specific conditions was not collected. For example, some participants were prescribed a tumor necrosis factor inhibitor for rheumatoid arthritis, whereas others received cyclosporine for a solid organ transplant. It is possible that immunosuppressed persons in better physical health were more likely to consent to the survey. As a result, these findings might overestimate the percentage of immunosuppressed persons performing cleanup activities.</p><p>Among a sample of immunosuppressed Houston area residents, many were exposed to mold and flood-damaged homes after Hurricane Harvey. Many residents at high risk for invasive mold infections engaged in activities to clean up mold and flood-damaged areas without wearing PPE recommended for otherwise healthy persons. Although recommendations for immunosuppressed persons are to avoid mold-contaminated sites, these findings might help prompt future studies on the knowledge, attitudes, and practices of PPE use among immunosuppressed persons in posthurricane settings and other locations experiencing flooding when complete avoidance of mold-contaminated sites is difficult. In turn, these studies could help inform future decisions about PPE recommendations for this population.</p><boxed-text id="Ba" position="float" orientation="portrait"><caption><title>Summary</title></caption><sec><title>What is already known about this topic?</title><p>Immunosuppressed persons are at risk for invasive mold infections and should avoid exposures such as those present during hurricane and flood cleanup activities.</p></sec><sec><title>What is added by this report?</title><p>Among a convenience sample of immunosuppressed residents in the Hurricane Harvey-affected area of Houston, Texas, 49% engaged in cleanup activities in water-damaged or mold-contaminated homes. Use of respiratory protection was low.</p></sec><sec><title>What are the implications for public health practice?</title><p>Health care providers should advise immunosuppressed persons to avoid exposure to water-damaged and mold-contaminated areas to reduce their risk for invasive mold infections.</p></sec></boxed-text></sec></body><back><ack><title>Acknowledgments</title><p>Kristy Murray, Baylor College of Medicine, Houston, Texas; Student Epidemic Intelligence Society, UTHealth School of Public Health, Houston, Texas; Andrew Berens, Tess Palmer, Geospatial Research, Analysis and Services Program, CDC; Kristin Cummings, Brett Green, NIOSH, CDC; John Butler, Angela Shippy, Kelley Boston, Sonia Bassett, Ahmed Al-Hammadi, Ryan Walsh, Elizabeth Reed, Patricia Tooley, Christina Solis, Sujatha Sridhar, Memorial Hermann-Texas Medical Center, Houston Texas.</p></ack><fn-group><fn id="FN1"><label>*</label><p>The N95 respirator is the most common particulate-filtering facepiece respirator and filters at least 95% of airborne particles. <ext-link ext-link-type="uri" xlink:href="https://www.cdc.gov/niosh/npptl/topics/respirators/disp_part/n95list1.html">https://www.cdc.gov/niosh/npptl/topics/respirators/disp_part/n95list1.html</ext-link>.</p></fn></fn-group><notes><fn-group><fn fn-type="COI-statement"><p>Luis Ostrosky-Zeichner reports grants and personal fees from Astellas, personal fees from Merck &#x00026; Co., grants and personal fees from Pfizer, grants and personal fees from Cidara, grants and personal fees from Scynexis, personal fees from F2G, grants from Amplyx, personal fees from Mayne, personal fees from Gilead, personal fees from NovaDigm, personal fees from United Medical, and personal fees from Stendhal outside the submitted work. Dimitrios P. Kontoyiannis reports honoraria for lectures from Merck &#x00026; Co., Gilead, and United Medicine and also reports consulting fees from Merck &#x00026; Co., Astellas, Cidara, Amplyx, and Mayne. No other potential conflicts of interest were disclosed.</p></fn></fn-group></notes><ref-list><title>References</title><ref id="R1"><label>1. </label><mixed-citation publication-type="web">National Weather Service<collab>. Major Hurricane Harvey</collab>&#x02014;August 25&#x02013;29, 2017. Corpus Christi, TX: National Weather Service Weather Forecast Office; <year>2017</year>
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