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<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" article-type="research-article"><?properties open_access?><front><journal-meta><journal-id journal-id-type="nlm-ta">MMWR Morb Mortal Wkly Rep</journal-id><journal-id journal-id-type="iso-abbrev">MMWR Morb. Mortal. Wkly. Rep</journal-id><journal-id journal-id-type="publisher-id">WR</journal-id><journal-title-group><journal-title>Morbidity and Mortality Weekly Report</journal-title></journal-title-group><issn pub-type="ppub">0149-2195</issn><issn pub-type="epub">1545-861X</issn><publisher><publisher-name>Centers for Disease Control and Prevention</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">30763297</article-id><article-id pub-id-type="pmc">6375654</article-id><article-id pub-id-type="publisher-id">mm6806a7</article-id><article-id pub-id-type="doi">10.15585/mmwr.mm6806a7</article-id><article-categories><subj-group subj-group-type="heading"><subject>Notes from the Field</subject></subj-group></article-categories><title-group><article-title><italic>Notes from the Field:</italic> Assessment of State-Level Influenza Season Severity &#x02014; Minnesota and Utah, 2017&#x02013;18 Influenza Season</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Hughes</surname><given-names>Michelle M.</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Doyle</surname><given-names>Joshua D.</given-names></name><degrees>MD</degrees><degrees>PhD</degrees><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>McCaffrey</surname><given-names>Keegan</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>McMahon</surname><given-names>Melissa</given-names></name><degrees>MPH</degrees><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Spencer</surname><given-names>Melanie</given-names></name><degrees>MPH</degrees><xref ref-type="aff" rid="aff5"><sup>5</sup></xref></contrib><contrib contrib-type="author"><name><surname>Martin</surname><given-names>Karen</given-names></name><degrees>MPH</degrees><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Reed</surname><given-names>Gregg M.</given-names></name><degrees>MPH</degrees><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Carmack</surname><given-names>Anna E.</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff6"><sup>6</sup></xref></contrib><contrib contrib-type="author"><name><surname>Garg</surname><given-names>Shikha</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Rolfes</surname><given-names>Melissa</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Reed</surname><given-names>Carrie</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Biggerstaff</surname><given-names>Matthew</given-names></name><degrees>ScD</degrees><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><aff><target id="aff1" target-type="aff"><sup>1</sup></target>Epidemic Intelligence Service, CDC; <target id="aff2" target-type="aff"><sup>2</sup></target>Influenza Division, National Center for Immunization and Respiratory Diseases, CDC; <target id="aff3" target-type="aff"><sup>3</sup></target>Utah Department of Health; <target id="aff4" target-type="aff"><sup>4</sup></target>Minnesota Department of Health, <target id="aff5" target-type="aff"><sup>5</sup></target>Salt Lake County Health Department, Salt Lake City, Utah; <target id="aff6" target-type="aff"><sup>6</sup></target>University of Maryland Medical Center, Baltimore, Maryland.</aff></contrib-group><author-notes><corresp id="cor1">Corresponding author: Michelle M. Hughes, <email xlink:href="MHughes7@cdc.gov">MHughes7@cdc.gov</email>, 404-639-3747.</corresp></author-notes><pub-date pub-type="epub"><day>15</day><month>2</month><year>2019</year></pub-date><pub-date pub-type="collection"><day>15</day><month>2</month><year>2019</year></pub-date><volume>68</volume><issue>6</issue><fpage seq="8">165</fpage><lpage>166</lpage><permissions><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/3.0/"><license-p>All material in the MMWR Series is in the public domain and may be used and reprinted without permission; citation as to source, however, is appreciated.</license-p></license></permissions></article-meta></front><body><p>The U.S. 2017&#x02013;18 influenza season was a high-severity season, with the highest number of outpatient visits for influenza-like illness<xref ref-type="fn" rid="FN1">*</xref> (ILI) since the 2009&#x02013;10 pandemic and the highest rate of influenza-associated hospitalizations since surveillance expanded to include adult hospitalizations during the 2005&#x02013;06 season (<xref rid="R1" ref-type="bibr"><italic>1</italic></xref>). The severe season was characterized by reports of strained emergency departments and hospitals and spot shortages of influenza antiviral medications (<xref rid="R2" ref-type="bibr"><italic>2</italic></xref>). Influenza activity can vary widely across geographic regions (<xref rid="R3" ref-type="bibr"><italic>3</italic></xref>), and local severity assessments might better guide public health actions and health care needs and support the development of tailored communication messages to prevent influenza morbidity and mortality. CDC assesses influenza season severity at the national level (<xref rid="R4" ref-type="bibr"><italic>4</italic></xref>),<xref ref-type="fn" rid="FN2"><sup>&#x02020;</sup></xref> but the applicability of this approach at state or local levels has not been tested.</p><p>In February 2018, field investigations were conducted in Minnesota and Utah to identify potential indicators of state-level influenza activity and pilot a state-level approach to assessing influenza season severity in real time. Indicators were selected using three criteria: 1) availability of data for 2017&#x02013;18 and at least five previous influenza seasons; 2) completeness and representativeness of data on observed influenza seasonality; and 3) timeliness. Two indicators selected in both states were weekly ILI activity (percentage of outpatient visits to sentinel providers for ILI) and influenza-associated hospitalizations (counts or population-based rates). A third indicator included weekly counts of influenza-associated deaths in Minnesota and weekly percentage of specimens testing positive for influenza reported by sentinel clinical laboratories in Utah. Using state-level data from five earlier seasons (2012&#x02013;13 through 2016&#x02013;17) and following previously published procedures (<xref rid="R3" ref-type="bibr"><italic>3</italic></xref>), indicator-specific intensity thresholds (ITs) for a 50% chance (IT<sub>50</sub>), 10% chance (IT<sub>90</sub>), and a 2% chance (IT<sub>98</sub>) of observing higher values during the 2017&#x02013;18 season were calculated. Severity was classified as low, moderate, high, or very high if at least two of three indicators peaked during the 2017&#x02013;18 season below their IT<sub>50</sub> value, between their IT<sub>50</sub> and IT<sub>90</sub> values, between their IT<sub>90</sub> and IT<sub>98</sub> values, and above their IT<sub>98</sub> value, respectively.</p><p>The interim severity of the 2017&#x02013;18 influenza season (assessed in mid-February 2018) for both Minnesota and Utah was categorized as high. As an example of one of the three indicators, influenza-associated hospitalizations through the end of the 2017&#x02013;18 season (May 2018) peaked above the IT<sub>90</sub> (Minnesota) and IT<sub>98</sub> (Utah) values (<xref ref-type="fig" rid="F1">Figure</xref>). End-of-season severity assessments for both states remained high, aligning with national trends and the subsequent high severity classification for the entire United States (<xref rid="R1" ref-type="bibr"><italic>1</italic></xref>).</p><fig id="F1" fig-type="figure" orientation="portrait" position="float"><label>FIGURE</label><caption><p>Influenza-associated hospitalizations indicators and intensity thresholds &#x02014; Minnesota<xref ref-type="fn" rid="FN1">*</xref><sup>,</sup><xref ref-type="fn" rid="FN2"><sup>&#x02020;</sup></xref> and Utah,<sup>&#x000a7;,&#x000b6;</sup> 2012&#x02013;18 influenza seasons</p><p content-type="fig-fn"><bold>Abbreviations:</bold> IT<sub>50</sub> = intensity threshold at which there is a 50% chance of observing a higher value during 2017&#x02013;18 based on historical (2012&#x02013;13 through 2016&#x02013;17) peak values; IT<sub>90</sub> = intensity threshold at which there is a 10% chance of observing a higher value during 2017&#x02013;18 based on historical (2012&#x02013;13 through 2016&#x02013;17) peak values; IT<sub>98</sub> = intensity threshold at which there is a 2% chance of observing a higher value during 2017&#x02013;18 based on historical (2012&#x02013;13 through 2016&#x02013;17) peak values.</p><p content-type="fig-fn">* Reported to the Minnesota Department of Health.</p><p content-type="fig-fn"><sup>&#x02020;</sup> Minnesota intensity thresholds: IT<sub>50</sub> = 255; IT<sub>90</sub> = 511; IT<sub>98</sub> = 778.</p><p content-type="fig-fn"><sup>&#x000a7;</sup> Reported to the Utah Department of Health.</p><p content-type="fig-fn"><sup>&#x000b6;</sup> Utah intensity thresholds: IT<sub>50</sub> = 3.66; IT<sub>90</sub> = 5.99; IT<sub>98</sub> = 8.06.</p></caption><graphic xlink:href="mm6806a7-F"/></fig><p>The national severity assessment framework was successfully adapted for use in Minnesota and Utah. Utah is piloting the report of the weekly severity assessments for the 2018&#x02013;19 season (<xref rid="R5" ref-type="bibr"><italic>5</italic></xref>). Additional states might find this method useful for improving local public health messaging, preparedness, and response during an influenza season and in the event of a pandemic. CDC continues to develop resources to support local assessments of influenza season severity; interested jurisdictions are encouraged to contact CDC&#x02019;s Influenza Division for assistance.</p></body><back><fn-group><fn id="FN1"><label>*</label><p>Fever (temperature &#x02265;100&#x000b0;F [37.8&#x000b0;C]) and a cough and/or a sore throat without a known cause other than influenza.</p></fn><fn id="FN2"><label>&#x02020;</label><p>Nationally, CDC assesses flu severity using three indicators: 1) percentage of visits to outpatient clinics for ILI; 2) the rates of influenza-associated hospitalizations; and 3) the percentage of deaths resulting from pneumonia or influenza that occurred during each season.</p></fn></fn-group><notes><fn-group><fn fn-type="COI-statement"><p>All authors have completed and submitted the ICMJE form for disclosure of potential conflicts of interest. Keegan McCaffrey reports grants from the Council of State and Territorial Epidemiologists during the course of the study. No other potential conflicts of interest were disclosed.</p></fn></fn-group></notes><ref-list><title>References</title><ref id="R1"><label>1. </label><mixed-citation publication-type="journal"><string-name><surname>Garten</surname>
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