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Postoperative complications affecting survival after cardiac arrest in general surgery patients

Filetype[PDF-412.48 KB]


  • English
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    Details:

    • Alternative Title:
      Anesth Analg
    • Personal Author:
    • Description:
      Background:

      Postoperative cardiac arrest is uncommon but associated with a high mortality risk in general surgery patients and is often preceded by postoperative complications. The relationships between prior complications and mortality after cardiac arrest in general surgery patients have not been completely evaluated.

      Methods:

      A retrospective, observational cohort of general surgery inpatients with cardiac arrest occurring after postoperative day (POD) #0 (and up to POD #30) was obtained from the 2012–2013 American College of Surgeons National Surgical Quality Improvement Program. Prior complication was defined as at least one of the following occurring prior to the POD of cardiac arrest: 1) acute kidney injury, 2) acute respiratory failure, 3) deep vein thrombosis/pulmonary embolus, 4) myocardial infarction, 5) sepsis/septic shock, 6) stroke, and/or 7) transfusion. The associations between prior complications and mortality after cardiac arrest were assessed using Cox proportional hazards models that adjusted for preoperative risk factors.

      Results:

      Of 1,352 patients with postoperative cardiac arrest, 746 patients (55%) developed at least one complication prior to cardiac arrest. Overall 30-day mortality was 71% (958/1,352) and was similar among patients with and without a prior complication (71% [533/746] vs. 70% [425/606], P=0.60). Patients with prior complications did not have an increased risk of mortality, compared to patients without prior complications, in adjusted Cox models (hazard ratio [HR] 1.03, 95% confidence interval [CI] 0.90–1.18, P=0.70). In addition, no prior complication was associated with increased mortality risk in individual analyses.

      Conclusions:

      Among general surgery patients with cardiac arrest after POD #0, complications occurring prior to cardiac arrest are common but are not associated with increased mortality risk.

    • Subjects:
    • Source:
      Anesth Analg. 126(3):858-864
    • Pubmed ID:
      28891912
    • Pubmed Central ID:
      PMC6378876
    • Document Type:
      Journal Article
    • Funding:
      R49 CE002096/CE/NCIPC CDC HHS/United States
    • Collection(s):
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