Details:

Alternative Title:
MMWR Morb Mortal Wkly Rep
Personal Author:
Slutsker, Jennifer Sanderson ; Hennessy, Robin R. ; Schillinger, Julia A.
Slutsker, Jennifer Sanderson ; Hennessy, Robin R. ; Schillinger, Julia A. Less -
Description:
Congenital syphilis occurs when syphilis is transmitted from a pregnant woman to her fetus; Congenital syphilis can be prevented through screening and treatment during pregnancy. Transmission to the fetus can occur at any stage of maternal infection, but is more likely during primary and secondary syphilis, with rates of Transmission up to 100% at these stages (1). Untreated syphilis during pregnancy can cause spontaneous abortion, stillbirth, and early infant death. During 2013-2017, national rates of Congenital syphilis increased from 9.2 to 23.3 cases per 100,000 live births (2), coinciding with increasing rates of primary and secondary syphilis among women of reproductive age (3). In New York City (NYC), cases of primary and secondary syphilis among women aged 15-44 years increased 147% during 2015-2016. To evaluate measures to prevent Congenital syphilis, the NYC Department of Health and Mental Hygiene (DOHMH) reviewed data for Congenital syphilis cases reported during 2010-2016 and identified patient-, provider-, and systems-level factors that contributed to these cases. During this period, 578 syphilis cases among pregnant women aged 15-44 years were reported to DOHMH; a Congenital syphilis case was averted or otherwise failed to occur in 510 (88.2%) of these pregnancies, and in 68, a case of Congenital syphilis occurred (eight cases per 100,000 live births).* Among the 68 pregnant women associated with these Congenital syphilis cases, 21 (30.9%) did not receive timely (≥45 days before delivery) prenatal care. Among the 47 pregnant women who did access timely prenatal care, four (8.5%) did not receive an initial syphilis test until <45 days before delivery, and 22 (46.8%) acquired syphilis after an initial nonreactive syphilis test. These findings support recommendations that health care providers screen all pregnant women for syphilis at the first prenatal care visit and then rescreen women at risk in the early third trimester.
Subjects:
[+]
Adolescent Adult Female Full Report Humans Practice Guidelines As Topic Pregnancy Pregnancy Complications, Infectious Prenatal Care Prenatal Diagnosis Risk Factors Syphilis, Congenital Time Factors Young Adult
Source:
MMWR Morb Mortal Wkly Rep. 2018; 67(39):1088-1093.
Pubmed ID:
30286056
Pubmed Central ID:
PMC6171893
Document Type:
Journal Article
Place as Subject:
New York City, New York
Collection(s):
Morbidity and Mortality Weekly Report (MMWR)
Main Document Checksum:
[+]
urn:sha256:9d3a6654693eb376aeab6887352100d62278a80528593f24f0097e3971fae37f
Download URL:
https://stacks.cdc.gov/view/cdc/59982/cdc_59982_DS1.pdf
File Type:

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