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<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" article-type="article-commentary"><?properties manuscript?><front><journal-meta><journal-id journal-id-type="nlm-journal-id">9706389</journal-id><journal-id journal-id-type="pubmed-jr-id">20773</journal-id><journal-id journal-id-type="nlm-ta">Int J Tuberc Lung Dis</journal-id><journal-id journal-id-type="iso-abbrev">Int. J. Tuberc. Lung Dis.</journal-id><journal-title-group><journal-title>The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease</journal-title></journal-title-group><issn pub-type="ppub">1027-3719</issn><issn pub-type="epub">1815-7920</issn></journal-meta><article-meta><article-id pub-id-type="pmid">29991386</article-id><article-id pub-id-type="pmc">6112608</article-id><article-id pub-id-type="doi">10.5588/ijtld.18.0415</article-id><article-id pub-id-type="manuscript">HHSPA985645</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Reflections on the State of the Art series on TB and migration, and
the way forward</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>SHAH</surname><given-names>SARITA</given-names></name><xref ref-type="aff" rid="A1">*</xref><xref ref-type="aff" rid="A2">&#x02020;</xref></contrib><contrib contrib-type="author"><name><surname>LANGE</surname><given-names>CHRISTOPH</given-names></name><xref ref-type="aff" rid="A3">&#x02021;</xref><xref ref-type="aff" rid="A4">&#x000a7;</xref><xref ref-type="aff" rid="A5">&#x000b6;</xref><xref ref-type="aff" rid="A6">#</xref></contrib><contrib contrib-type="author"><name><surname>L&#x000d6;NNROTH</surname><given-names>KNUT</given-names></name><xref ref-type="aff" rid="A7">**</xref></contrib></contrib-group><aff id="A1"><label>*</label>Centers for Disease Control and Prevention</aff><aff id="A2"><label>&#x02020;</label>Emory University Rollins School of Public Health,
Atlanta, GA, USA</aff><aff id="A3"><label>&#x02021;</label>Division of Clinical Infectious Diseases, Research
Center Borstel</aff><aff id="A4"><label>&#x000a7;</label>German Center for Infection Research (DZIF),
Clinical Tuberculosis Center, Borstel</aff><aff id="A5"><label>&#x000b6;</label>International Health/Infectious Diseases, University
of L&#x000fc;beck, L&#x000fc;beck, Germany</aff><aff id="A6"><label>#</label>Department of Medicine, Karolinska Institute</aff><aff id="A7"><label>**</label>Department of Public Health Sciences, Karolinska
Institute, Stockholm, Sweden <email>bwg2@cdc.gov</email></aff><pub-date pub-type="nihms-submitted"><day>20</day><month>8</month><year>2018</year></pub-date><pub-date pub-type="ppub"><day>01</day><month>8</month><year>2018</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>8</month><year>2019</year></pub-date><volume>22</volume><issue>8</issue><fpage>829</fpage><lpage>829</lpage><!--elocation-id from pubmed: 10.5588/ijtld.18.0415--><related-article related-article-type="commentary-article" xlink:href="29991390" ext-link-type="pmid" id="ra1" xlink:type="simple"/></article-meta></front><body><p id="P1">OVER THE PAST YEAR, the Grey <italic>Journal</italic> has taken a bold step
towards recognizing the critical importance of migrant health as a public health
priority. Since the launch of the State of the Art (SoA) series on TB and migration in
August 2017, the challenge of global migration for TB care and prevention has not
diminished. Millions have experienced migration&#x02014;either voluntarily or
forced&#x02014;due to economic hardship, military conflicts, or other
disasters.<sup><xref rid="R1" ref-type="bibr">1</xref></sup> Migration has been
a fundamental human experience since the beginning of time and is undoubtedly likely to
continue. Therefore, as the SoA series has demonstrated, addressing migrant-specific
health needs is a shared responsibility of the global health community that entails not
only efforts in low-burden countries that receive the majority of migrants, but also
strengthening of TB care and prevention in high-burden countries to lower overall TB
incidence and minimize risk in future migrants.</p><p id="P2">In the final article of the series, in this issue of the
<italic>Journal</italic>, Shete and colleagues provide a conceptual framework for
countries to develop a migrant-inclusive TB research agenda addressing critical areas
where evidence gaps remain.<sup><xref rid="R2" ref-type="bibr">2</xref></sup> They focus
on epidemiologic research, including operational and implementation science along the
full cascade of care, in addition to social protection research, which is particularly
important in this highly vulnerable population. Importantly, the authors tackle the
practical issue of operationalizing migrant-inclusive research agendas that, by their
very nature, often require cross-country collaboration. A key challenge, however, is
that research priorities in migrant-receiving (high or low TB burden countries) and
migrant-origin countries may differ, and must therefore be harmonized at the outset in
order to foster collaboration. An innovative approach is proposed where by regional
research &#x02018;hubs&#x02019; or platforms would be established that are tailored to
addressing the evidence gaps in this population, along with translating and
disseminating knowledge that is relevant to the region. Such hubs are already starting
to emerge.<sup><xref rid="R3" ref-type="bibr">3</xref></sup> This shared approach would
serve to benefit not only the migrant population, but also the communities and countries
from which they originate and to which they travel.</p><p id="P3">In today&#x02019;s increasingly interconnected world, as
migration&#x02014;temporary or permanent&#x02014;surges throughout all regions, countries
should consider migrant-specific health needs as part of their general health systems.
For TB programs, in particular, fundamental challenges remain in the prompt diagnosis
and treatment of latent infection with <italic>Mycobacterium tuberculosis</italic>
(LTBI) and active TB, which are amplified in this population. As innovations emerge in
more sensitive predictive tests for LTBI, shorter regimens for treating LTBI, and
shorter and safer regimens for drug-susceptible and drug-resistant TB, the migrant
population should be prioritized for implementation of these advances. The goals of the
End TB strategy cannot be achieved unless we succeed in eliminating TB in migrant
populations. We hope that this series will continue to stimulate the research required
to fill the remaining knowledge gaps and inform evidence and human-rights based
policy.</p></body><back><fn-group><fn id="FN1"><p id="P4"><italic>Disclaimer:</italic> The findings and conclusions in this report
are those of the authors and do not necessarily represent the official position
of the Centers for Disease Control and Prevention.</p></fn><fn fn-type="COI-statement" id="FN2"><p id="P5"><italic>Conflicts of interest:</italic> none declared.</p></fn></fn-group><ref-list><title>References</title><ref id="R1"><label>1</label><mixed-citation publication-type="book"><collab>United Nations</collab>.
<source>International Migration Report</source>. <publisher-loc>New York,
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<comment><ext-link ext-link-type="uri" xlink:href="https://www.un.org/development/desa/publications/international-migration-report-2017.html">https://www.un.org/development/desa/publications/international-migration-report-2017.html</ext-link></comment>
<date-in-citation>Accessed June 2018</date-in-citation>.</mixed-citation></ref><ref id="R2"><label>2</label><mixed-citation publication-type="journal"><name><surname>Shete</surname><given-names>P</given-names></name>, <name><surname>Boccia</surname><given-names>D</given-names></name>, <name><surname>Dhavan</surname><given-names>P</given-names></name>, <etal/>
<article-title>Defining a migrant-inclusive tuberculosis research agenda to end
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