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Establishing a Timeline to Discontinue Routine Testing of Asymptomatic Pregnant Women for Zika Virus Infection — American Samoa, 2016–2017
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Mar 24 2017
Source: MMWR Morb Mortal Wkly Rep. 66(11):299-301. -
Alternative Title:MMWR Morb Mortal Wkly Rep
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Description:The first patients with laboratory-confirmed cases of Zika Virus disease in American Samoa had symptom onset in January 2016 (1). In response, the American Samoa Department of Health (ASDoH) implemented mosquito control measures (1), strategies to protect pregnant women (1), syndromic Surveillance based on electronic health record (EHR) reports (1), Zika Virus tTesting of persons with one or more signs or symptoms of Zika Virus disease (fever, rash, arthralgia, or conjunctivitis) (1-3), and routine tTesting of all asymptomatic pregnant women in accordance with CDC guidance (2,3)| All collected blood and urine specimens were shipped to the Hawaii Department of Health Laboratory for Zika Virus tTesting and to CDC for confirmatory tTesting. Early in the response, collection and tTesting of specimens from pregnant women was prioritized over the collection from symptomatic nonpregnant patients because of limited tTesting and shipping capacity. The weekly numbers of suspected Zika Virus disease cases declined from an average of six per week in January-February 2016 to one per week in May 2016. By August, the EHR-based syndromic Surveillance (1) indicated a return to pre-outbreak levels. The last Zika Virus disease case detected by real-time, reverse transcription-polymerase chain reaction (rRT-PCR) occurred in a patient who had symptom onset on June 19, 2016. In August 2016, ASDoH requested CDC support in assessing whether local Transmission had been reduced or interrupted and in proposing a timeline for discontinuation of routine tTesting of asymptomatic pregnant women. An end date (October 15, 2016) was determined for active mosquito-borne Transmission of Zika Virus and a timeline was developed for discontinuation of routine screening of asymptomatic pregnant women in American Samoa (conception after December 10, 2016, with permissive tTesting for asymptomatic women who conceive through April 15, 2017).
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Pubmed ID:28333910
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Pubmed Central ID:PMC5657887
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