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In vivo measurement of bone manganese and association with manual dexterity: a pilot study
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  1. In vivo neutron activation analysis of bone manganese in workers
    Personal Author:
    Liu, Yingzi; Rolle-McFarland, Danelle; Mostafaei, Farshad; Zhou, Yuanzhong; Li, Yan; Zheng, Wei; Wells, Ellen; Nie, Linda H;
    Published:
    March 23 2018
    Source:
    Physiol Meas. 39(3):035003
    Description:
    Objective: : Manganese (Mn) is a neurotoxin. However, the impact of elevated, chronic Mn exposure is not well understood, partially due to the lack of a cumulative exposure biomarker. To address this gap, our group developed a compact in vivo neutron...
    File Type:
    Filetype[PDF - 684.55 KB]
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    The association of bone, fingernail and blood manganese with cognitive and olfactory function in Chinese workers
    Personal Author:
    Rolle-McFarland, Danelle; Liu, Yingzi; Mostafaei, Farshad; Zauber, S. Elizabeth; Zhou, Yuanzhong; Li, Yan; Fan, Quiyan; Zheng, Wei; Nie, Linda H.; Wells, Ellen M.;
    Published:
    February 21 2019
    Source:
    Sci Total Environ. 666:1003-1010
    Description:
    Occupational manganese (Mn) exposure has been associated with cognitive and olfactory dysfunction; however, few studies have incorporated cumulative biomarkers of Mn exposure such as bone Mn (BnMn). Our goal was to assess the cross-sectional associat...
    Public Access
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    May 20, 2020
  3. Neurological outcomes associated with low-level manganese exposure in an inception cohort of asymptomatic welding trainees
    Personal Author:
    Baker, Marissa G; Criswell, Susan R; Racette, Brad A; Simpson, Christopher D; Sheppard, Lianne; Checkoway, Harvey; Seixas, Noah S;
    Published:
    Nov 07 2014
    Source:
    Scand J Work Environ Health. 41(1):94-101.
    Description:
    Objective : Long-term, high-level exposure to manganese (Mn) is associated with impaired central nervous system (CNS) function. We quantitatively explored relations between low-level Mn exposure and selected neurological outcomes in a longitudinal in...
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    Filetype[PDF - 234.96 KB]
  4. Development of a transportable neutron activation analysis system to quantify manganese in bone in vivo: feasibility and methodology
    Personal Author:
    Liu, Yingzi; Koltick, David; Byrne, Patrick; Wang, Haoyu; Zheng, Wei; Nie, Linda H;
    Published:
    Oct 28 2013
    Source:
    Physiol Meas. 2013; 34(12):1593-1609.
    Description:
    This study was conducted to investigate the methodology and feasibility of developing a transportable neutron activation analysis (NAA) system to quantify manganese (Mn) in bone using a portable deuterium-deuterium (DD) neutron generator as the neutr...
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  5. Sex differences in sensitivity to prenatal and early childhood manganese exposure on neuromotor function in adolescents
    Personal Author:
    Chiu, Yueh-Hsiu Mathilda; Henn, Birgit Claus; Hsu, Hsiao-Hsien Leon; Pendo, Mathew P.; Coull, Brent A.; Austin, Christine; Cagna, Giuseppa; Fedrighi, Chiara; Placidi, Donatella; Smith, Donald R.; Wright, Robert O.; Lucchini, Roberto G.; Arora, Manish;
    Published:
    Sep 18 2017
    Source:
    Environ Res. 159:458-465.
    Description:
    Introduction : While studies have suggested that exposure to manganese (Mn) may be associated with neurodevelopment in school-age children, there is limited information on prenatal and postnatal Mn exposures and tremor or motor function in children. ...
    File Type:
    Filetype[PDF - 359.23 KB]