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A Strategy for assigning new NIOSH skin notations
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  • Description:
    1. Introduction. -- 2. Assigning Skin Notations -- Appendix A: Protocols Used in Studies of Health Effects from Skin Exposure and the Determination of Criteria Derived for Assigning Skin Notations -- Appendix B: Algorithm for estimating skin absorption and systemic toxicity and suggested application for assigning SYS notations -- Appendix C: Identifying skin corrosives and sensitizers using physicochemical properties and structure activity relationship-based analysis. -- Appendix D: Selecting and Prioritizing Candidate Chemicals. -- Appendix E: Guidelines and Criteria for the Search Strategy, Evaluation, and Selection of Supporting Data Used for the Assignment of Skin Notations -- Appendix F: Example of Assigning New NIOSH Skin Notations and Format of the Skin Notation Profile -- Appendix G: Supplemental information

    NIOSH skin notations are hazard warnings used worldwide to alert workers and employers to the health risks of skin exposures to chemicals in the workplace. This Current Intelligence Bulletin (CIB) provides the rationale for assigning new NIOSH skin notations. The new system reflects the current state of scientific knowledge and involves critical evaluation of scientific data so that scientists can assign multiple skin notations that distinguish between the systemic, direct, and sensitizing effects of skin exposures to chemicals. This new strategy is a form of hazard identification that advances our understanding of the hazards posed by skin exposures to chemicals. Such improved understanding will enable us to implement better risk management practices and controls for the prevention of workplace skin diseases and other occupational diseases where skin exposure may contribute to disease development.

    NIOSHTIC No 20035667

  • Content Notes:
    Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health. ; "This document was prepared by the Education and Information Division (EID), Paul Schulte, Ph.D., Director. Heinz W. Alhers, J.D., Chen-Peng Chen, Ph.D., Eugene Demchuk, Ph.D., and G. Scott Dotson, Ph.D. were the principle authors." - p. xvi ; Includes bibliographical references (p. 12-14). ; NIOSH ; 8/24/2015 ; NIOSH ;
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