Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Poowanawittayakom, Nongnooch ; Dutta, Anamika ; Stock, Shannon ; Touray, Sunkaru ; Ellison, Richard T. ; ... More +
Poowanawittayakom, Nongnooch ; Dutta, Anamika ; Stock, Shannon ; Touray, Sunkaru ; Ellison, Richard T. ; Levitz, Stuart M. ; Less -
Description:
The epidemic of illicit intravenous drug use (IVDU) in the United States has been accompanied by a surge in drug overdose deaths and infectious sequelae. Candida albicans infections were associated with injection of contaminated impure brown heroin in the 1970s-1990s; however, candidiasis accompanying IVDU became considerably rarer as the purity of the heroin supply increased. We reviewed cases of candidemia occurring over a recent 7-year period in persons >14 years of age at a tertiary care hospital in central Massachusetts. Of the 198 patients with candidemia, 24 cases occurred in patients with a history of IVDU. Compared with non-IVDU patients, those with a history of IVDU were more likely to have non-albicans Candida, be co-infected with hepatitis C, and have end-organ involvement, including endocarditis and osteomyelitis. Thus, IVDU appears to be reemerging as a risk factor for invasive candidiasis.
Subject:
[+]
Adult
Candidemia
Communicable Diseases, Emerging
Comorbidity
Drug Users
Female
Humans
Male
Middle Aged
Patient Outcome Assessment
Risk Assessment
Risk Factors
Substance Abuse, Intravenous/complications
Synopsis
Young Adult

Source:
Emerg Infect Dis. 24(4):631-637.
Pubmed ID:
29553923
Pubmed Central ID:
PMC5875264
Document Type:
Journal Article ;
Place as Subject:
Massachusetts ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:e172e688343a8c4bb06dc19809286c117d1ba5942b681f00c588e0ed74e69327
File Type:

Supporting Files

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