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Increases in the competitive fitness of West Nile virus isolates after introduction into California
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  1. Comparing Competitive Fitness of West Nile Virus Strains in Avian and Mosquito Hosts
    Personal Author:
    Worwa, Gabriella; Wheeler, Sarah S.; Brault, Aaron C.; Reisen, William K.;
    Published Date:
    May 12 2015
    Source:
    PLoS One. 10(5).
    Description:
    Enzootic transmission of West Nile virus (WNV; Flaviviridae, Flavivirus) involves various species of birds and ornithophilic mosquitoes. Single nucleotide substitutions in the WNV genome may impact viral fitness necessary for WNV adaptation and evolu...
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  2. Experimental Evolution of an RNA Virus in Wild Birds: Evidence for Host-Dependent Impacts on Population Structure and Competitive Fitness
    Personal Author:
    Grubaugh, Nathan D.; Smith, Darci R.; Brackney, Doug E.; Bosco-Lauth, Angela M.; Fauver, Joseph R.; Campbell, Corey L.; Felix, Todd A.; Romo, Hannah; Duggal, Nisha K.; Dietrich, Elizabeth A.; Eike, Tyler; Beane, Jennifer E.; Bowen, Richard A.; Black, William C.; Brault, Aaron C.; Ebel, Gregory D.;
    Published Date:
    May 20 2015
    Source:
    PLoS Pathog. 11(5).
    Description:
    Within hosts, RNA viruses form populations that are genetically and phenotypically complex. Heterogeneity in RNA virus genomes arises due to error-prone replication and is reduced by stochastic and selective mechanisms that are incompletely understoo...
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  3. West Nile viral infection of equids
    Personal Author:
    Angenvoort, J.; Brault, A.C.; Bowen, R.A.; Groschup, M.H.;
    Published Date:
    Aug 28 2013
    Source:
    Vet Microbiol. 167(0):168-180.
    Description:
    West Nile virus (WNV) is a flavivirus transmitted between certain species of birds and mosquito vectors. Tangential infections of equids and subsequent equine epizootics have occurred historically. Although the attack rate has been estimated to be be...
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  4. Sequence Analyses of 2012 West Nile Virus Isolates from Texas Fail to Associate Viral Genetic Factors with Outbreak Magnitude
    Personal Author:
    Duggal, Nisha K.; D'Anton, Mary; Xiang, Jeannie; Seiferth, Robyn; Day, Joanne; Nasci, Roger; Brault, Aaron C.;
    Published Date:
    Jul 01 2013
    Source:
    Am J Trop Med Hyg. 2013; 89(2):205-210.
    Description:
    In 2012, Texas experienced the largest outbreak of human West Nile encephalitis (WNE) since the introduction of West Nile virus (WNV) in 2002. Despite the large number of WNV infections, data indicated the rate of reported WNE among human cases was n...
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  5. Review of Climate, Landscape, and Viral Genetics as Drivers of the Japanese Encephalitis Virus Ecology
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    Le Flohic, Guillaume; Porphyre, Vincent; Barbazan, Philippe; Gonzalez, Jean-Paul;
    Published Date:
    Sep 12 2013
    Source:
    PLoS Negl Trop Dis. 2013; 7(9).
    Description:
    The Japanese encephalitis virus (JEV), an arthropod-born Flavivirus, is the major cause of viral encephalitis, responsible for 10,000-15,000 deaths each year, yet is a neglected tropical disease. Since the JEV distribution area has been large and con...
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