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Lineage-Specific Real-Time RT-PCR for Yellow Fever Virus Outbreak Surveillance, Brazil
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Nov 17 2017
Source: Emerg Infect Dis. 23(11):1867-1871.
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Alternative Title:Emerg Infect Dis
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Description:The current yellow fever outbreak in Brazil prompted widespread yellow fever virus (YFV) vaccination campaigns, imposing a responsibility to distinguish between vaccine- and wild-type YFV-associated disease. We developed novel multiplex real-time reverse transcription PCRs that differentiate between vaccine and American wild-type YFV. We validated these highly specific and sensitive assays in an outbreak setting.
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Pubmed ID:28949285
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Pubmed Central ID:PMC5652426
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