TABLE 5. Reported cases of notifiable diseases and rates per 100,000, by sex, excluding U.S. territories - - United States, 2016 column labels in same order that data fields appears in each record below: Disease Female, No. Female, Rate Male, No. Male, Rate Sex not stated, No. Total, No. tab delimited data: Anthrax — — — — — — Arboviral diseases, Chikungunya virus disease 134 0.08 113 0.07 — 247 Arboviral diseases, Eastern equine encephalitis virus disease, Neuroinvasive 1 0.00 6 0.00 — 7 Arboviral diseases, Eastern equine encephalitis virus disease, Non-neuroinvasive — — — — — — Arboviral diseases, Jamestown Canyon virus disease, Neuroinvasive 2 0.00 5 0.00 — 7 Arboviral diseases, Jamestown Canyon virus disease, Non-neuroinvasive 1 0.00 7 0.00 — 8 Arboviral diseases, La Crosse virus disease, Neuroinvasive 10 0.01 21 0.01 — 31 Arboviral diseases, La Crosse virus disease, Non-neuroinvasive — — 4 0.00 — 4 Arboviral diseases, Powassan virus disease, Neuroinvasive 7 0.00 14 0.01 — 21 Arboviral diseases, Powassan virus disease, Non-neuroinvasive 1 0.00 — — — 1 Arboviral diseases, St. Louis encephalitis virus disease, Neuroinvasive 3 0.00 4 0.00 — 7 Arboviral diseases, St. Louis encephalitis virus disease, Non-neuroinvasive — — 1 0.00 — 1 Arboviral diseases, West Nile virus disease, Neuroinvasive 463 0.28 845 0.53 — 1,308 Arboviral diseases, West Nile virus disease, Non-neuroinvasive 362 0.22 479 0.30 — 841 Arboviral diseases, Western equine encephalitis virus disease, Neuroinvasive — — — — — — Arboviral diseases, Western equine encephalitis virus disease, Non-neuroinvasive — — — — — — Babesiosis, Total 659 0.57 1,246 1.10 5 1,910 Babesiosis, Confirmed 536 0.46 1,045 0.92 4 1,585 Babesiosis, Probable 123 0.11 201 0.18 1 325 Botulism, Total 82 0.05 118 0.07 1 201 Botulism, Foodborne 7 0.00 24 0.02 — 31 Botulism, Infant 67 3.45 76 3.74 1 144 Botulism, Other (wound & unspecified) 8 0.00 18 0.01 — 26 Brucellosis 49 0.03 77 0.05 1 127 Campylobacteriosis 28,398 17.31 31,424 19.75 298 60,120 Chancroid 1 0.00 6 0.00 — 7 Chlamydia trachomatis infection 1,072,719 653.90 522,870 328.69 2,765 1,598,354 Cholera 8 0.00 7 0.00 — 15 Coccidioidomycosis * 5,106 7.70 6,701 10.33 22 11,829 Cryptosporidiosis, Total 6,904 4.21 6,454 4.06 95 13,453 Cryptosporidiosis, Confirmed 4,346 2.65 4,254 2.67 37 8,637 Cryptosporidiosis, Probable 2,558 1.56 2,200 1.38 58 4,816 Cyclosporiasis 325 0.22 211 0.15 1 537 Dengue virus infections, Dengue † 447 0.27 456 0.29 — 903 Dengue virus infections, Dengue-like illness † 16 0.01 24 0.02 — 40 Dengue virus infections, Severe dengue † 4 0.00 6 0.00 — 10 Diphtheria — — — — — — Ehrlichiosis and Anaplasmosis, Anaplasma phagocytophilum infection 1,596 1.01 2,473 1.61 82 4,151 Ehrlichiosis and Anaplasmosis, Ehrlichia chaffeensis infection 529 0.33 846 0.55 2 1,377 Ehrlichiosis and Anaplasmosis, Ehrlichia ewingii infection 11 0.01 11 0.01 — 22 Ehrlichiosis and Anaplasmosis, Undetermined ehrlichiosis/anaplasmosis 96 0.06 104 0.07 — 200 Giardiasis 6,490 5.04 9,770 7.82 50 16,310 Gonorrhea 197,499 120.39 270,033 169.75 982 468,514 Haemophilus influenzae, invasive disease, All ages, all serotypes 2,634 1.61 2,233 1.40 28 4,895 Haemophilus influenzae, invasive disease, Age <5 years, Serotype b 11 0.11 19 0.19 — 30 Haemophilus influenzae, invasive disease, Age <5 years, Non-b serotype 67 0.69 92 0.90 — 159 Haemophilus influenzae, invasive disease, Age <5 years, Nontypeable 89 0.91 106 1.04 1 196 Haemophilus influenzae, invasive disease, Age <5 years, Unknown serotype 83 0.85 103 1.01 1 187 Hansen's disease 17 0.01 46 0.03 15 78 Hantavirus infection, non-hantavirus pulmonary syndrome 2 0.00 4 0.00 — 6 Hantavirus pulmonary syndrome 13 0.01 18 0.01 — 31 Hemolytic uremic syndrome post-diarrheal 181 0.11 125 0.08 1 307 Hepatitis, A, acute § 897 0.55 1,107 0.70 3 2,007 Hepatitis, B, acute § 1,252 0.77 1,957 1.24 9 3,218 Hepatitis, B, perinatal infection § 11 0.28 21 0.52 — 32 Hepatitis, C, acute § 1,310 0.85 1,627 1.08 5 2,942 Human immunodeficiency virus diagnoses 6,631 4.04 28,144 17.69 — 34,775 Influenza-associated pediatric mortality 48 0.13 34 0.09 — 82 Invasive pneumococcal disease, All ages 8,400 6.86 9,125 7.71 101 17,626 Invasive pneumococcal disease, All ages, Confirmed 8,390 6.85 9,112 7.70 101 17,603 Invasive pneumococcal disease, All ages, Probable 10 0.01 13 0.01 — 23 Invasive pneumococcal disease, Age <5 years 484 0.37 652 0.51 6 1,142 Invasive pneumococcal disease, Age <5 years, Confirmed 481 6.17 650 7.98 6 1,137 Invasive pneumococcal disease, Age <5 years, Probable 3 0.04 2 0.02 — 5 Legionellosis 2,458 1.50 3,679 2.31 4 6,141 Leptospirosis 18 0.01 60 0.05 — 78 Listeriosis 401 0.24 383 0.24 2 786 Lyme disease, Total 15,307 9.37 20,567 12.99 555 36,429 Lyme disease, Confirmed 10,971 6.72 14,810 9.35 422 26,203 Lyme disease, Probable 4,336 2.65 5,757 3.64 133 10,226 Malaria 743 0.45 1,194 0.75 18 1,955 Measles, Total 24 0.01 61 0.04 — 85 Measles, Indigenous 19 0.01 49 0.03 — 68 Measles, Imported 5 0.00 12 0.01 — 17 Meningococcal disease, All serogroups 173 0.11 202 0.13 — 375 Meningococcal disease, Serogroups ACWY 62 0.04 64 0.04 — 126 Meningococcal disease, Serogroup B 41 0.02 45 0.03 — 86 Meningococcal disease, Other serogroups 9 0.01 12 0.01 — 21 Meningococcal disease, Unknown serogroup 61 0.04 81 0.05 — 142 Mumps 3,147 1.92 3,194 2.01 28 6,369 Novel Influenza A virus infections 9 0.01 14 0.01 — 23 Pertussis 9,900 6.03 8,029 5.05 43 17,972 Plague — — 4 0.00 — 4 Poliomyelitis, paralytic — — — — — — Poliovirus infection, nonparalytic — — — — — — Psittacosis 8 0.01 4 0.00 — 12 Q fever, Total 34 0.02 130 0.08 — 164 Q fever, Acute 27 0.02 105 0.07 — 132 Q fever, Chronic 7 0.00 25 0.02 — 32 Rabies, Human — — — — — — Rubella — — 1 0.00 — 1 Rubella, congenital syndrome 2 0.10 — — — 2 Salmonellosis 28,379 17.30 25,090 15.77 381 53,850 Severe acute respiratory syndrome-associated coronavirus disease — — — — — — Shiga toxin-producing Escherichia coli ¶ 4,521 2.76 3,614 2.27 34 8,169 Shigellosis 10,579 6.45 10,359 6.51 159 21,097 Smallpox — — — — — — Spotted fever rickettsiosis, Total 1,442 0.88 2,823 1.79 4 4,269 Spotted fever rickettsiosis, Confirmed 46 0.03 108 0.07 — 154 Spotted fever rickettsiosis, Probable 1,396 0.86 2,715 1.72 4 4,115 Streptococcal toxic shock syndrome 146 0.14 137 0.13 — 283 Syphilis, Total, all stages ** 14,848 9.05 72,433 45.53 761 88,042 Syphilis, Congenital — — — — 628 628 Syphilis, Primary and secondary 3,049 1.86 24,724 15.54 41 27,814 Tetanus 11 0.01 22 0.01 1 34 Toxic shock syndrome (other than Streptococcal) 28 0.02 11 0.01 1 40 Trichinellosis 6 0.00 20 0.01 — 26 Tuberculosis 3,633 2.21 5,639 3.54 — 9,272 Tularemia 76 0.05 153 0.10 1 230 Typhoid fever 177 0.11 197 0.12 2 376 Vancomycin-intermediate Staphylococcus aureus 46 0.04 62 0.05 — 108 Vancomycin-resistant Staphylococcus aureus — — — — — — Varicella morbidity 4,330 3.28 4,581 3.58 42 8,953 Varicella mortality U U U U U U Vibriosis, Total 437 0.27 824 0.53 12 1,273 Vibriosis, Confirmed 422 0.26 807 0.52 12 1,241 Vibriosis, Probable 15 0.01 17 0.01 — 32 Viral hemorrhagic fevers, Crimean-Congo hemorrhagic fever virus — — — — — — Viral hemorrhagic fevers, Ebola virus — — — — — — Viral hemorrhagic fevers, Guanarito virus — — — — — — Viral hemorrhagic fevers, Junin virus — — — — — — Viral hemorrhagic fevers, Lassa virus — — — — — — Viral hemorrhagic fevers, Lujo virus — — — — — — Viral hemorrhagic fevers, Machupo virus — — — — — — Viral hemorrhagic fevers, Marburg virus — — — — — — Viral hemorrhagic fevers, Sabia virus — — — — — — Yellow fever — — 1 0.00 — 1 Zika virus, Zika virus disease, congenital †† 17 0.88 13 0.64 — 30 Zika virus, Zika virus disease, non-congenital 3,290 2.01 1,842 1.16 — 5,132 Zika virus, Zika virus infection, congenital †† 23 1.19 22 1.08 — 45 Zika virus, Zika virus infection, non-congenital 852 0.52 58 0.04 1 911 —: No reported cases U: Unavailable * Reportable in <25 states. † Total number of reported laboratory-positive dengue cases, including all confirmed cases [by anti-dengue virus (DENV) molecular diagnostic methods or seroconversion of anti-DENV IgM] and all probable cases (by a single, positive anti-DENV IgM). § Chronic hepatitis B and C data are not included in NNDSS tables but reported case counts are included in the annual Summary of Viral Hepatitis, published online by CDC's Division of Viral Hepatitis, available at https://www.cdc.gov/hepatitis/statistics/2015surveillance/index.htm. ¶ Includes Escherichia coli O157:H7; shiga toxin-positive, serogroup non-O157; and shiga toxin positive, not serogrouped. ** Includes syphilis of all stages, including cases where stage of syphilis is not stated. †† Data reported to ArboNET using the national surveillance case definition for congenital Zika virus disease or infection (CSTE Position Statement 16-ID-01). Additional data reported to the US Zika Pregnancy Registry for outcomes of pregnancies with laboratory evidence of possible Zika virus infection are available at https://www.cdc.gov/zika/reporting/pregnancy-outcomes.html. Cases reported to the US Zika Pregnancy Registry might not meet the national surveillance case definition for congenital Zika virus disease or infection. Notes: These are annual cases of selected infectious national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published. Cases are reported by state health departments to CDC weekly. Annual data may differ from previously reported weekly and quarterly data due to revision of information and delayed reporting. The list of national notifiable infectious diseases and conditions for 2016 and their national surveillance case definitions are available at https://wwwn.cdc.gov/nndss/conditions/notifiable/2016/infectious-diseases/, https://wwwn.cdc.gov/nndss/conditions/notifiable/2016/infectious-diseases/. This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved in 2015 by CSTE for national surveillance, that were implemented in January 2016, including updated surveillance case definitions for acute hepatitis C and chronic hepatitis C virus infections. 2016 data are reported through June 30, 2017. Publication criteria for the finalized 2016 data are available at https://wonder.cdc.gov/nndss/documents/2016_NNDSS_Publication_Criteria.pdf, /nndss/documents/2016_NNDSS_Publication_Criteria.pdf. See also https://wwwn.cdc.gov/nndss/document/guide_to_interpreting_provisional_and_finalized_nndss_data_tables.pdf, Guide to Interpreting Provisional and Finalized NNDSS Data. Population estimates for incidence rates are July 1st, 2016 estimates obtained from the National Center for Health Statistics (NCHS) postcensal estimates of the resident population of the United States for July 1, 2011 - July 1, 2016, by year, county, single year of age (range: 0 to 85 years), bridged-race (white, black or African American, American Indian or Alaska Native, Asian, or Pacific Islander), Hispanic ethnicity (not Hispanic or Latino, Hispanic or Latino), and sex (Vintage 2016), prepared under a collaborative arrangement with the U.S. Census Bureau. Population estimates for states as of June 26, 2017 are available at https://www.cdc.gov/nchs/nvss/bridged_race/data_documentation.htm, https://www.cdc.gov/nchs/nvss/bridged_race/data_documentation.htm. Population estimates for territories are the 2016 mid-year estimates from the U.S. Census Bureau International Data Base accessed on July 24, 2017 at https://www.census.gov/population/international/data/idb/informationGateway.php, https://www.census.gov/population/international/data/idb/informationGateway.php. The choice of population denominators for incidence is based on the availability of population data at the time of publication preparation. NNDSS data displayed in the annual tables are accurate as of October 17, 2017; source data may be updated as additional information is received. Annual tables for 2016 are available on https://wonder.cdc.gov/nndss/nndss_annual_tables_menu.asp, CDC WONDER. Annual summary reports from 1993-2015 are available as published in the https://www.cdc.gov/mmwr/mmwr_nd/index.html, MMWR. Annual summary reports from 1952-1992 are available as published in the MMWR in the https://stacks.cdc.gov/, CDC Stacks. https://wwwn.cdc.gov/nndss/, National Notifiable Diseases Surveillance System Provided by https://wonder.cdc.gov, CDC WONDER