Prevalence of enteric infections among hospitalized patients in two referral hospitals in Ghana

Details

• Alternative Title:
  BMC Res Notes
• Personal Author:
  Akuffo, R. ; Armah, G. ; Clemens, M. ; Kronmann, K. C. ; Jones, A. H. ; Agbenohevi, P. ; Sagoe, K. ; Puplampu, N. ; Talla Nzussouo, N. ; Ampofo, W. ; Koram, K. ; Duplessis, C. ; Dueger, E.
• Description:
  Background
  
  Diarrhea is an important cause of morbidity and mortality worldwide. In Africa and Ghana in particular, it is estimated to contribute directly to 19 and 25% of pediatric mortality among children under 5 years, respectively.
  
  Methods
  
  Surveillance for hospitalized acute diarrheal illness was initiated in November 2010 through October 2012 in a referral hospital in southern Ghana, and a teaching hospital in northern Ghana. Consenting hospitalized patients who met a standardized case definition for acute diarrheal illness provided demographic and epidemiologic data. Stool samples were collected and tested by culture for bacteria and by enzyme immunoassays for a panel of viruses and parasites.
  
  Results
  
  A total of 429 patients were enrolled; 216 (50.3%) were under 5 years, and 221 (51.5%) were females. Stool samples were received from 153 patients. Culture isolates included Shigella sp., Salmonella spp., Plesiomonas sp. and Vibrio cholerae. Of 147 samples tested for viruses, 41 (27.9%) were positive for rotaviruses, 11 (7.5%) for astroviruses, 10 (6.8%) for noroviruses, and 8 (5.4%) for adenoviruses. Of 116 samples tested for parasitic infections; 4 (3.4%) were positive for Cryptosporidium sp. and 3 (2.6%) for Giardia lamblia. Of the enrolled patients, 78.8% had taken antibiotics prior to sample collection.
  
  Conclusions
  
  Diarrheal pathogens were identified across all ages, however, predominantly (81%) in the children under 5 years of age. This study also detected high antibiotic use which has the potential of increasing antibiotic resistance. The most common enteric pathogen detected (49.4%) was rotavirus.
  
  Electronic supplementary material
  
  The online version of this article (doi:10.1186/s13104-017-2621-x) contains supplementary material, which is available to authorized users.
  
  
• Subjects:
  Adolescent Adult Aged Aged, 80 And Over Child Child, Preschool Diarrhea Feces Female Hospitals Humans Male Middle Aged Prevalence Rotavirus Young Adult

  More +
• Source:
  BMC Res Notes. 10.
• Pubmed ID:
  28716138
• Pubmed Central ID:
  PMC5514524
• Document Type:
  Journal Article
• Place as Subject:
  Ghana
• Volume:
  10
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:57896b9cadfa6b8bdbc35781b82a25422ed4bc508202375620fe27959d3998b6
• Download URL:
  https://stacks.cdc.gov/view/cdc/46941/cdc_46941_DS1.pdf
• File Type:
  [PDF - 1.40 MB ]