Details:

Alternative Title:
BMC Res Notes
Publisher's site:
http://dx.doi.org/10.1186/s13104-017-2621-x
Personal Author:
Akuffo, R.; Armah, G.; Clemens, M.; Kronmann, K. C.; Jones, A. H.; ... More +
Akuffo, R.; Armah, G.; Clemens, M.; Kronmann, K. C.; Jones, A. H.; Agbenohevi, P.; Sagoe, K.; Puplampu, N.; Talla Nzussouo, N.; Ampofo, W.; Koram, K.; Duplessis, C.; Dueger, E.; Less -
Description:
Background Diarrhea is an important cause of morbidity and mortality worldwide. In Africa and Ghana in particular, it is estimated to contribute directly to 19 and 25% of pediatric mortality among children under 5 years, respectively. Methods Surveillance for hospitalized acute diarrheal illness was initiated in November 2010 through October 2012 in a referral hospital in southern Ghana, and a teaching hospital in northern Ghana. Consenting hospitalized patients who met a standardized case definition for acute diarrheal illness provided demographic and epidemiologic data. Stool samples were collected and tested by culture for bacteria and by enzyme immunoassays for a panel of viruses and parasites. Results A total of 429 patients were enrolled; 216 (50.3%) were under 5 years, and 221 (51.5%) were females. Stool samples were received from 153 patients. Culture isolates included Shigella sp., Salmonella spp., Plesiomonas sp. and Vibrio cholerae. Of 147 samples tested for viruses, 41 (27.9%) were positive for rotaviruses, 11 (7.5%) for astroviruses, 10 (6.8%) for noroviruses, and 8 (5.4%) for adenoviruses. Of 116 samples tested for parasitic infections; 4 (3.4%) were positive for Cryptosporidium sp. and 3 (2.6%) for Giardia lamblia. Of the enrolled patients, 78.8% had taken antibiotics prior to sample collection. Conclusions Diarrheal pathogens were identified across all ages, however, predominantly (81%) in the children under 5 years of age. This study also detected high antibiotic use which has the potential of increasing antibiotic resistance. The most common enteric pathogen detected (49.4%) was rotavirus. Electronic supplementary material The online version of this article (doi:10.1186/s13104-017-2621-x) contains supplementary material, which is available to authorized users.
Subject:
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Diarrhea
Enteric
Hospitalized
Infections
Pathogens
Prevalence
Research Article
Surveillance

Source:
BMC Res Notes. 10.;
Pubmed ID:
28716138
Pubmed Central ID:
PMC5514524
Document Type:
Journal Article;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:57896b9cadfa6b8bdbc35781b82a25422ed4bc508202375620fe27959d3998b6
File Type:

Supporting Files

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