Major Persistent 5′ Terminally Deleted Coxsackievirus B3 Populations in Human Endomyocardial Tissues

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Bouin, Alexis ; Nguyen, Yohan ; Wehbe, Michel ; Renois, Fanny ; Fornes, Paul ; Bani-Sadr, Firouze ; Metz, Damien ; Andreoletti, Laurent
• Description:
  We performed deep sequencing analysis of the enterovirus 5' noncoding region in cardiac biopsies from a patient with dilated cardiomyopathy. Results displayed a mix of deleted and full-length coxsackievirus B3, characterized by a low viral RNA load (8.10(2) copies/μg of nucleic acids) and a low viral RNA positive-sense to RNA negative-sense ratio of 4.8.
• Subjects:
  5′ Terminally Deleted Populations Coxsackievirus B3 Dispatch Endomyocardial Enterovirus Heart Human Idiopathic Dilated Cardiomyopathy Major Persistent 5′ Terminally Deleted Coxsackievirus B3 Populations In Human Endomyocardial Tissues Viruses
• Source:
  Emerg Infect Dis. 22(8):1488-1490.
• Pubmed ID:
  27434549
• Pubmed Central ID:
  PMC4982168
• Document Type:
  Journal Article
• Volume:
  22
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:d876fe50d2e61d89c68a2bc3fc973009bf13360279ac231cfb9eda4bdc53cf4f
• Download URL:
  https://stacks.cdc.gov/view/cdc/40868/cdc_40868_DS1.pdf
• File Type:
  [PDF - 432.96 KB ]