Major Persistent 5′ Terminally Deleted Coxsackievirus B3 Populations in Human Endomyocardial Tissues

Bouin, Alexis; Nguyen, Yohan; Wehbe, Michel; Renois, Fanny; Fornes, Paul; Bani-Sadr, Firouze; Metz, Damien; Andreoletti, Laurent

doi:10.3201/eid2208.160186

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Major Persistent 5′ Terminally Deleted Coxsackievirus B3 Populations in Human Endomyocardial Tissues

Published Date:

Aug 2016

Publisher's site:

http://dx.doi.org/10.3201/eid2208.160186 New Site Icon

Source:

Emerg Infect Dis. 22(8):1488-1490.

[PDF - 432.96 KB]

Details:

Personal Authors:

Bouin, Alexis ; Nguyen, Yohan ; Wehbe, Michel ; Renois, Fanny ; Fornes, Paul ; ... More ▼

Keywords:

[+]

Pubmed ID:

27434549

Pubmed Central ID:

PMC4982168

Description:

We performed deep sequencing analysis of the enterovirus 5' noncoding region in cardiac biopsies from a patient with dilated cardiomyopathy. Results displayed a mix of deleted and full-length coxsackievirus B3, characterized by a low viral RNA load (8.10(2) copies/μg of nucleic acids) and a low viral RNA positive-sense to RNA negative-sense ratio of 4.8.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

16-0186-F.gif	image/gif
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16-0186-Techapp-s1.pdf	application/pdf
16-0186.nxml	application/octet-stream

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