CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.
As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.
i
Mortality From Neurodegenerative Diseases in a Cohort of US Flight Attendants
-
May 17 2016
-
-
Source: Am J Ind Med. 59(7):532-537
[PDF-72.29 KB]
Details:
-
Alternative Title:Am J Ind Med
-
Personal Author:
-
Description:Background
Concern exists about the potential chronic neurological effects among aircrew of exposure to chemical contaminants from engine oil in aircraft cabin air. We evaluated mortality from neurodegenerative diseases among 11,311 former US flight attendants.
Methods
Vital status was ascertained through 2007, and life table analyses were conducted to obtain standardized mortality ratios (SMRs).
Results
Amyotrophic lateral sclerosis (ALS) mortality was over twice as high in the cohort as in the US general population, based on nine observed ALS deaths. There was no clear pattern in risk when SMRs for ALS were stratified by exposure duration. Mortality from other neurodegenerative diseases was not elevated.
Conclusions
Our findings are limited due to small numbers of observed deaths and reliance on mortality data, but suggest that flight attendants may have an increased risk of ALS. Additional research is needed.
-
Subjects:
-
Source:
-
Pubmed ID:27184412
-
Pubmed Central ID:PMC4915549
-
Document Type:
-
Funding:
-
Place as Subject:
-
Volume:59
-
Issue:7
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
